5 research outputs found

    Hypnotic recall: a positive criterion in the differential diagnosis between epileptic and pseudoepileptic

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    Objective: To assess whether the Movement ABC can be used to monitor individual change in motor performance. Design: Motor-impaired children were tested three times in succession with the Movement ABC without any intervention. Setting: Two schools for special education and one school for children who are chronically ill. Subjects: Three girls and 20 boys aged 6-8 years. Main outcome measures: Scores were measured per item (0→5), added to cluster scores (0→10 or 15), added to form the total scores (0→40). Mean scores, standard errors of measurement (SEMs) and least detectable differences (LDDs) were calculated per item, per cluster and for the total scores. A repeated measures analysis of variance was performed to test for the effects of time. Results: The total scores improved significantly from the first session (mean: 15.4 points) to the second (mean: 13.3), but not from the second to the third (mean: 13.2). Average item scores ranged from 0.6 to 2.7 points with SEMs of 0.79→1.54 and LDDs of 2.20→4.27. Average cluster scores ranged from 3.4 to 5.3 with SEMs of 1.51→1.84 and LDDs of 4.18→5.11. The SEM of the total scores equalled 3.13 with an LDD of 8.68. Conclusions: The total score of the Movement ABC is sufficiently sensitive to monitor individual change; the cluster scores have moderate sensitivity and individual items are inappropriate to monitor individual change. The significant effect of time is interpreted as an effect of learning

    Association of Oxidative Stress, Iron, and Centralized Fat Mass in Healthy Postmenopausal Women

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    Objective: Centralized adiposity, insulin resistance, excess iron, and elevated oxidative stress place postmenopausal women at risk for atherosclerotic cardiovascular disease (CVD). The objective of this study was to determine the relationship among excess iron, oxidative stress, and centralized fat mass in healthy postmenopausal women. Methods: The parent project recruited healthy women for a randomized, double-blind, clinical trial designed to examine the effect of soy isoflavones on bone. At baseline ( n = 122), we measured three antioxidant enzymes, iron status indices (serum ferritin among others), oxidative stress indices (oxidized low-density lipoprotein [oxLDL], urinary isoprostanes [PGF2α], protein carbonyls, DNA damage), and waist, hip, and thigh fat mass using dual-energy x-ray absorptiometry (DXA). We calculated insulin resistance using the homeostasis model assessment (HOMA). Multiple regression analysis was used to determine the CVD risk factors that contributed to oxidative stress and centralized fat mass (waist + hip/thigh = AndGynFM ratio). Results: Almost 14% ( p \u3c 0.0005) of the variability in oxLDL was accounted for by AndGynFM ratio (6.1%, p \u3c 0.0005), age (4.0%, p = 0.012), and serum iron (2.8%, p = 0.053). Similarly, 16% ( p \u3c 0.0001) of the variability in PGF2α was accounted for by the AndGynFM ratio (4.8%, p = 0.011), HOMA (3.9%, p = 0.021), and serum iron (2.7%, p = 0.054). We accounted for 33% ( p ≤ 0.0001) of the variability in AndGynFM ratio by high-density lipoprotein cholesterol (HDL-C) (4.3%, p = 0.008), ferritin (4.9%, p = 0.005), HOMA (4.5%, p = 0.006), oxLDL (2.6%, p = 0.04), and PGF2α (3.0%, p = 0.025). Conclusions: Our study suggests that reducing centralized fat mass and maintaining a favorable lipid profile, antioxidant status, and iron status all may be important in protecting postmenopausal women from atherosclerotic CVD. [ABSTRACT FROM AUTHOR
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