Integrative Review of Riparian Buffers Benefits in Urbanized Watersheds

Riparian buffers or riparian corridors are areas of vegetation in the floodplains and areas surrounding a stream. By the early 2000s, numerous national reports and studies of riparian buffer benefits established that vegetation near streams is helpful in protecting the stream from increasing urban runoff, minimizing bank erosion, reducing flooding, and improving overall water quality. However, influential studies concluded that buffer benefits dwindle as urbanization increases, eventually becoming ineffective. This study evaluates more recent research that suggests riparian buffers are more effective at countering urbanization impacts than previously understood, and considers the extent to which we can quantify these benefits and identify the factors that maximize their effectiveness (i.e. greater efficiency based on buffer distance from the stream, extent of stream setbacks, and percentage of impervious cover in the area). Much of the research has been conducted in the Kansas City area in the Blue River Watershed, which begins in Kansas and flows into Missouri River east of downtown Kansas City, Missouri. About 800,000 residents live in the watershed, which includes some of the region’s fastest growing areas. It is critical to protect this major resource, and other regional rivers and streams, for residents of the Kansas City Metropolitan area and the ecosystems that depend on them. It is also critical to provide the latest and best information to the community-of-practice currently updating regional stormwater management planning and design guidance.

Simple Biosphere Model version 4.2 (SiB4) technical description

The Simple Biosphere Model (SiB4) is a mechanistic, prognostic land surface model that integrates heterogeneous land cover, environmentally responsive prognostic phenology, dynamic carbon allocation, and cascading carbon pools from live biomass to surface litter to soil organic matter. By combining biogeochemical, biophysical, and phenological processes, SiB4 predicts vegetation and soil moisture states, land surface energy and water budgets, and the terrestrial carbon cycle. Rather than relying on satellite data, SiB4 fully simulates the terrestrial carbon cycle by using the carbon fluxes to determine the above and belowground biomass, which in turn feeds back to impact carbon assimilation and respiration. Every 10-minute time-step, SiB4 computes the albedo, radiation budget, hydrological cycle, layered temperatures, and soil moisture, as well as the resulting energy exchanges, moisture fluxes, carbon fluxes, and carbon pool transfers. Photosynthesis depends directly on environmental factors (humidity, moisture, and temperature) and aboveground biomass; and carbon uptake is determined using enzyme kinetics and stomatal physiology. Carbon release and pool transfers depend on assimilation rate, day length, moisture, phenology, temperature, and pool size. Once daily the net assimilated carbon is allocated to the live pools depending on phenology, soil moisture, and temperature; all live and dead pools are updated, including any necessary carbon transfers between pools; and the land surface state and related properties are revised. The new LAI and pools are then used for sub-hourly assimilation and respiration, completing the carbon cycle and providing self-consistent predicted vegetation states, soil hydrology, carbon pools, and land-atmosphere exchanges

The evolution of gift cards in secondary markets and money services

This paper reviews gift cards and the regulations associated with these instruments in financial transactions. One important consideration of gift cards involves secondary markets and money services business. While the accounting of gift cards by retailers is easy when they are redeemed, gift cards become problematic when breakage (non-redemption) occurs. In addition to large organized exchanges for gift cards, many prospective sellers and buyers have turned to non-mainstream dealers to handle situations relating to the non-redemption of the gift card. This has caused gift cards to become an increasingly important player in the secondary market. Another important observation with these instruments involves the true cost to buyers. Most consumers fail to consider opportunity costs and alternatives. Since gift cards are perceived differently than cash, opportunity cost consideration should be viewed differently to determine the effective price value

TransCom 3 experimental protocol

July 2000.Includes bibliographical references.Sponsored by NSF award OCE-9900310, and NOAA NA67RJ0152 Amend. 30

Interannual variability of photosynthesis across Africa and its attribution

Africa is thought to be a large source of interannual variability in the global carbon cycle, only vaguely attributed to climate fluctuations. This study uses a biophysical model, Simple Biosphere, to examine in detail what specific factors, physiological (acute stress from low soil water, temperature, or low humidity) and biophysical (low vegetation radiation use), are responsible for spatiotemporal patterns of photosynthesis across the African continent during the period 1982-2003. Acute soil water stress emerges as the primary factor driving interannual variability of photosynthesis for most of Africa. Southern savannas and woodlands are a particular hot spot of interannual variability in photosynthesis, owing to high rainfall variability and photosynthetic potential but intermediate annual rainfall. Surprisingly low interannual variability of photosynthesis in much of the Sudano-Sahelian zone derives from relatively low vegetation cover, pronounced humidity stress, and somewhat lower rainfall variability, whereas perennially wet conditions diminish interannual variability in photosynthesis across much of the Congo Basin and coastal West Africa. Though not of focus here, the coefficient of variation in photosynthesis is notably high in drylands and desert margins (i.e., Sahel, Greater Horn, Namib, and Kalahari) having implications for supply of food and fiber. These findings emphasize that when considering impacts of climate change and land surface feedbacks to the atmosphere, it is important to recognize how vegetation, climate, and soil characteristics may conspire to filter or dampen ecosystem responses to hydroclimatic variability. Copyright 2008 by the American Geophysical Union

Inhibition of Insulin‐Like Growth Factor 1 Receptor Enhances the Efficacy of Sorafenib in Inhibiting Hepatocellular Carcinoma Cell Growth and Survival

Hepatocellular carcinoma (HCC) is the fifth most common primary cancer and second largest cause of cancer‐related death worldwide. The first‐line oral chemotherapeutic agent sorafenib only increases survival in patients with advanced HCC by less than 3 months. Most patients with advanced HCC have shown limited response rates and survival benefits with sorafenib. Although sorafenib is an inhibitor of multiple kinases, including serine/threonine‐protein kinase c‐Raf, serine/threonine‐protein kinase B‐Raf, vascular endothelial growth factor receptor (VEGFR)‐1, VEGFR‐2, VEGFR‐3, and platelet‐derived growth factor receptor β, HCC cells are able to escape from sorafenib treatment using other pathways that the drug insufficiently inhibits. The aim of this study was to identify and target survival and proliferation pathways that enable HCC to escape the antitumor activity of sorafenib. We found that insulin‐like growth factor 1 receptor (IGF1R) remains activated in HCC cells treated with sorafenib. Knockdown of IGF1R sensitizes HCC cells to sorafenib treatment and decreases protein kinase B (AKT) activation. Overexpression of constitutively activated AKT reverses the effect of knockdown of IGF1R in sensitizing HCC cells to treatment with sorafenib. Further, we found that ceritinib, a drug approved by the U.S. Food and Drug Administration for treatment of non‐small cell lung cancer, effectively inhibits the IGF1R/AKT pathway and enhances the inhibitory efficacy of sorafenib in human HCC cell growth and survival in vitro, in a xenograft mouse model and in the c‐Met/β‐catenin‐driven HCC mouse model. Conclusion: Our study provides a biochemical basis for evaluation of a new combination treatment that includes IGF1R inhibitors, such as ceritinib and sorafenib, in patients with HCC

Investigators share improved understanding of the North American Carbon Cycle

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94828/1/eost16014.pd

Temperature-dependent release of ATP from human erythrocytes: Mechanism for the control of local tissue perfusion

Copyright @ 2012 The AuthorsThis article has been made available through the Brunel Open Access Publishing Fund.Human limb muscle and skin blood flow increases significantly with elevations in temperature, possibly through physiological processes that involve temperature-sensitive regulatory mechanisms. Here we tested the hypothesis that the release of the vasodilator ATP from human erythrocytes is sensitive to physiological increases in temperature both in vitro and in vivo, and examined potential channel/transporters involved. To investigate the source of ATP release, whole blood, red blood cells (RBCs), plasma and serum were heated in vitro to 33, 36, 39 and 42°C. In vitro heating augmented plasma or ‘bathing solution’ ATP in whole blood and RBC samples, but not in either isolated plasma or serum samples. Heat-induced ATP release was blocked by niflumic acid and glibenclamide, but was not affected by inhibitors of nucleoside transport or anion exchange. Heating blood to 42°C enhanced (P < 0.05) membrane protein abundance of cystic fibrosis transmembrane conductance regulator (CFTR) in RBCs. In a parallel in vivo study in humans exposed to whole-body heating at rest and during exercise, increases in muscle temperature from 35 to 40°C correlated strongly with elevations in arterial plasma ATP (r2 = 0.91; P = 0.0001), but not with femoral venous plasma ATP (r2 = 0.61; P = 0.14). In vitro, however, the increase in ATP release from RBCs was similar in arterial and venous samples heated to 39°C. Our findings demonstrate that erythrocyte ATP release is sensitive to physiological increases in temperature, possibly via activation of CFTR-like channels, and suggest that temperature-dependent release of ATP from erythrocytes might be an important mechanism regulating human limb muscle and skin perfusion in conditions that alter blood and tissue temperature.This article is made available through the Brunel Open Access Publishing Fund