Mean Platelet Volume Values and Its Effects on Prognosis in Patients with Acute Ischemic Stroke

Objective:Stroke is a rapid onset of focal or global loss of cerebral function and is the most common cause of mortality and morbidity in adulthood cancer and heart disease patients. Although it has been reported that mean platelet volume (MPV) values may be an independent risk factor for the severity and prognosis of stroke, the results of previous studies are inconsistent. The aim of the present study was to determine the MPV values of ischemic stroke patients which reflects the activity and function of platelets and to observe its effect on clinical outcomes.Method:Sixty-two acute ischemic stroke patients were recruited for the study. Clinical information, MPV, platelet, white blood cell (WBC) and neutrophil, CRP and troponin-T levels were obtained.Results:The mean ± standard deviation age was 72.4±12.6 years. At the end of the study, 28 patients were discharged and 34 patients passed away. The frequency of bilateral stroke was higher in deceased patients (p=0.005). In addition, platelet counts were significantly higher in discharged patients (p=0.016). At first admission, MPV values were 10.59±1.01 fL in discharged patients and 11.29±1.12 fL in deceased patients (p=0.029). At the end of the study, MPV values were measured as 11.46±1.28 fL in deceased patient sand 10.47±0.74 fL in discharged patients (p0.05).Conclusion:Our study indicated that MPV and platelet levels may be associated with mortality in acute ischemic stroke patients and can be used as prognostic markers

Analysis of the effects of the COVID-19 process on the turkish financial system by TodaYamamoto method

Son iki yılda insanlığın en önemli sorunlarından biri haline gelen COVID-19 pandemisinin oluşturduğu etkilerin uzun süre devam edeceği tahmin edilmektedir. COVID-19 salgını ortaya çıktığı andan bu yana milyonlarca insanın ölümüne, işini kaybetmesine, eğitimin, üretimin ve turizmin durmasına, üretim maliyetlerinin artmasına, üretim-tüketim ile arz-talep dengelerinin bozulmasına ve büyüme değerlerinin negatife dönmesine neden olmuştur. Başlangıçta sadece insan sağlığını tehdit eden COVID-19 pandemisi, zamanla ekonomilerin reel ve finansal sektörlerine de sıçramıştır. Dünya genelinde panik ve belirsizlik ortamına neden olan COVID-19, finansal sistemde önemli etkiler doğurması nedeniyle finansal piyasaların yeni “Siyah Kuğu”su olarak adlandırılmaya başlanmıştır. Buradan hareketle, ele alınan çalışmanın amacı, COVID-19 pandemisinin, geçmişte pek çok kez kriz yaşamış bir ülke olarak dikkati çeken Türkiye’nin finansal sistemi üzerindeki etkisini incelemek olarak belirlenmiştir. Çalışmada kullanılan değişkenler COVID-19 hasta ve vefat sayıları, altın fiyatları, ABD doları-TL kuru, Euro-TL kuru ve BIST-100 endeks değerleridir. Çalışmanın amacı doğrultusunda, değişkenlere ait 06.04.2020– 02.07.2021 dönemini içeren günlük veriler kullanılarak Toda-Yamamoto nedensellik analizi uygulanmıştır. Elde edilen sonuçlara göre COVID-19 hasta ve vefat sayılarından gram altın fiyatlarına, ABD doları döviz kuruna ve Euro döviz kuruna doğru nedensel bir ilişki bulunmaktadır.It is estimated that the effects of the COVID-19 pandemic, which has become one of the most important problems of humanity in the last two years, will continue for a long time. Since the outbreak of COVID19, millions of people died, lost their jobs, education, production, and tourism stopped, production costs increased, production-consumption and supply-demand balances deteriorated, and growth values turned negative. The COVID-19 pandemic, which initially only threatened human health, spread over time to the real and financial sectors of economies. COVID-19, which has caused panic and uncertainty around the world, has begun to be called the new "Black Swan" of financial markets due to its significant effects on the financial system. From this point of view, the aim of the study was determined to examine the impact of the COVID-19 pandemic on the financial system of Turkey, which has attracted attention as a country that has experienced many crises in the past. The variables used in the study are the number of COVID-19 patients and deaths, gold prices, USD-TL exchange rates, Euro-TL exchange rates and BIST-100 index values. In line with the purpose of the study, Toda-Yamamoto causality analysis was applied by using daily data including the period of 06.04.2020–02.07.2021 belonging to the variables. According to the obtained results, there is a causal relationship from the number of COVID-19 patients and deaths to gold prices, US dollar exchange rate and Euro exchange rate

Self Silencing in Young Women

The concept of self silencing which has been taken attention mainly in the cross cultural contexts has been investigated for a while. Self silencing mainly experienced by women refers to the fact that women care more about the wishes, expectations and needs of others in their close relationships. Avoiding conflict, maintaining the relationship and obtaining a sense of trust seem to be the underlying factors. Additionally it is also proposed that women who suppress their own voices and put the voices of others to the fore, view themselves as sacrifices in relationships and have an externalized and divided self perception. In this study, the characteristics of self-silencing, the two-dimensional autobiographical model which is frequently mentioned in recent years, and self-silencing in the cultural and feminist context are reviewed. Relationship between self silencing and identity development, and gender roles in women are reviewed in this paper

A NEW INTEGRATED GREY MCDM MODEL: CASE OF WAREHOUSE LOCATION SELECTION

Warehouses link suppliers and customers throughout the entire supply chain. The location of the warehouse has a significant impact on the logistics process. Even though all other warehouse activities are successful, if the product dispatched from the warehouse fails to meet the customer needs in time, the company may face with the risk of losing customers. This affects the performance of the whole supply chain therefore the choice of warehouse location is an important decision problem. This problem is a multi-criteria decision-making (MCDM) problem since it involves many criteria and alternatives in the selection process. This study proposes an integrated grey MCDM model including grey preference selection index (GPSI) and grey proximity indexed value (GPIV) to determine the most appropriate warehouse location for a supermarket. This study aims to make three contributions to the literature. PSI and PIV methods combined with grey theory will be introduced for the first time in the literature. In addition, GPSI and GPIV methods will be combined and used to select the best warehouse location. In this study, the performances of five warehouse location alternatives were assessed with twelve criteria. Location 4 is found as the best alternative in GPIV. The GPIV results were compared with other grey MCDM methods, and it was found that GPIV method is reliable. It has been determined from the sensitivity analysis that the change in criteria weights causes a change in the ranking of the locations therefore GPIV method was found to be sensitive to the change in criteria weights

Knowledge levels and associated factors about newborn care of pregnants following by hospital

AMAÇ: Bu araştırmada bir hastanenin obstetrik polikliniğinde takip edilen gebelerin yenidoğan bakımı konusundaki bilgi düzeylerinin ve etkileyen faktörlerin belirlenmesi amaçlanmıştı. GEREÇ VE YÖNTEMLER: Tanımlayıcı tipteki bu araştırma bir hastanenin Obstetrik Polikliniği’nde takipli ve araştırmaya katılmayı kabul eden 118 gebe ile yürütüldü. Araştırmanın verileri 23 soru ve iki bölümden oluşan anket formunun yüzyüze gözlem altında uygulanması yoluyla toplandı. Verilerin istatistik analizlerinde tanımlayıcı istatistikler, ki-kare ve Fisher’in kesin testi kullanıldı ve p<0.05 istatistiksel anlamlılık düzeyi olarak kabul edildi. BULGULAR: Katılımcıların %40,7’si üniversite mezunu iken, %54,2’si çalışmakta idi. Sadece %13,6’sı bebek bakımı ile ilgili eğitim almıştı. Katılımcıların %84,7’si kundaklama, %72,9’u anne sütü verme zamanı, %71,2’si gün içinde emzirilme sayısı ve %66,1’i de yenidoğana yapılacak aşılar konularında doğru bilgi sahibi idi. Yenidoğanın bakımı ile ilgili konularla eğitim düzeyi, çalışma durumu ve bebek bakımıyla ilgili eğitim alma durumu arasında anlamlı farklılık bulundu (p<0.005). SONUÇ: Araştırmamızda katılımcıların yenidoğan bakımıyla ilgili bilgi düzeyleri yüksek bulunmuştur. Eğitim düzeyi yüksek, çalışan ve bebek bakımı eğitimi almış olanların daha bilgili olmaları, ülkemizde bu konuda eğitim verilmesinin ve kadının statüsünün arttırılmasının önemini göstermektedir.OBJECTIVE: The purpose of this study was to determined knowledge levels and associated factors about newborn care of pregnants following by obstetrics policlinic of a hospital. MATERIALS AND METHODS: This descriptive study was performed with 118 voluntary pregnants following by Obstetric Policlinic of a hospital. Study data was collected by a two part questionnaire which had 23 questions by using face to face interview. The data was evaluated by descriptive statatistics, chi square and Fisher exact tests. and p<0.05 has been accepted significany level. RESULTS: Of 40.7% participants were graduated from university and 54.2% of them employed. Only 13.6% of them had an education about newborn care. 84.7% of them had correct knowledge about swaddling, 72.9% of them had correct knowledge about breastfeeding time, 71.2% of them had correct knowledge about frequency of breastfeeding in a day and 66.1% of them had correct knowledge about vaccination of the newborn. There were significant differences between newborn care knowledge and education level, employment and having an education about newborn care (p<0.005). CONCLUSION: We find newborn knowledge levels of the participants high. Participants who are high educated, employed and have an education about newborn care have more knowledge about this subject. This results show us the importance of giving education about this subject and raising status of women in our country

Maternal Psychological Problems Associated with Neonatal Intensive Care Admission

Background. Mothers of infants admitted to a neonatal intensive care unit (NICU) are believed to have heightened distress. The purpose of this paper was to determine depression and anxiety symptoms and attachment style in NICU mothers. Methods. The NICU group consisted of mothers whose infants were admitted to the NICU and the control group consisted of mothers of healthy term infants. The psychosocial assessments were done at the first month. Results. The mean Edinburgh Postpartum Depression (EPDS) score of NICU mothers was significantly higher than that of the control group mothers (9.6 ± 5.6 versus 7.3 ± 4.9, P = .005). NICU mothers who had high EPDS (≥13) scores had significantly higher anxiety scores and insecure attachment style in comparison to the subgroup of NICU mothers who had low EPDS scores. Conclusion. Mothers of NICU babies had higher EPDS scores. Mothers who had higher EPDS scores had higher anxiety scores as well. These NICU mothers should receive appropriate counseling during the hospitalization of their babies

Cut-Off Values of Specific IgE and Skin Prick Test to Predict Oral Food Challenge Positivity in Children with Cow's Milk Allergy

Objective: The cut-off values for the skin prick test diameters and cow's milk-specific IgE measurements are used to predict the result of the oral food challenge test for the diagnosis of cow's milk allergy. This study aimed to determine the diagnostic values of skin prick test and cow's milk-specific IgE according to age groups and compare the diagnostic powers of these 2 methods. Materials and Methods: In total, 153 children who had a preliminary diagnosis of cow's milk allergy were evaluated. Group A (n = 90) consisted of cow's milk allergy patients whose diagnosis was confirmed by a positive oral food challenge or a history of anaphylaxis. Group B (n = 63) was composed of patients with a negative oral food challenge. The demographic, clinical, and laboratory findings of 2 groups were compared. Results: The cut-off points for cow's milk-specific IgE and cow's milk-skin prick test were determined as >2.12 kUA/L and >5 mm, respectively. The area under the curve was 0.844 for cow's milk-skin prick test (sensitivity 73%, specificity 84%) and 0.745 for cow's milk-specific IgE (sensitivity 67%, specificity 86%). The diagnostic power of skin prick test was determined to be higher when compared to cow's milk-specific IgE (P=.02). According to the predicted probability curves, decision points for cow's milk-specific IgE and cow's milk-skin prick test with 95% probability were determined as follows, respectively: for 24 months: 44.1 kUA/, 15.1 mm. The lowest cut-off value with a positive predictive value of 95% and a specificity of 96% was found in patients 3.3 kUA/L) Conclusion: The use of high probability diagnostic values of communities for specific IgE and skin prick test along with a significant clinical history may provide accurate and rapid diagnosis of cow's milk allergy and facilitate patient follow-up