452 research outputs found
Administrative Leadership in Times of a Global Health Crisis: Voices and Images From the Field
The novel coronavirus (COVID-19) pandemic took the world into crisis. We saw the virus alter a multitude of spheres worldwide, including our healthcare, economies, politics, social processes, and education. In fact, the impact of COVID-19 on educational administration took our leaders into forced emergency measures. Our study aims to better understand the experiences of educational administrators under crisis to ascertain what might be learned on how educational institutions may better respond to the crisis in the future. These stories were collected from educational leaders, both from K-12 and higher education, throughout the United States. In brief, this article is framed in the theory and literature associated with the complexity of leading in times of crisis. We explore the resiliency of leadership forged in crisis and the rethinking of administrative as administration as a caring and trustful acts. Our research began as a hermeneutic phenomenological interview study, but transitions into a two-round project, where after the first interview, participants were invited to share some images that typify and speak to the experiences being educational administrators during this time. We are engaged in sensitive topics that are ongoing and changing. Moreover, throughout, we are asking for images that speak to their experiences. Across both K-12 and higher education, our results indicated varied responses, from immediate to delayed administrative action. However, albeit they looked contextually different, there are clear indications the participants valued continuous, transparent communication, authentic caring, trust, and agency. In our discussion, we elaborate on the distinction between what the institutional response was as compared to what was valued by our educational leaders. Finally, as a contribution to the field, we seek to provide guidance for future administrators in crisis based on our own experiences and the recommendations provided by our educational leaders
Who leads the leaders? K-12 and higher education leadership under duress
Beginning in March of 2020, the world of education was disrupted and potentially altered forever. This project considers the ways that leaders in both K-12 and higher education with the United States of America engaged in leadership to engage with their community. Using a two-part project, we worked with 15 educational leaders to better understand the impact that the COVID- 19 pandemic had on their work. In this paper, we outline the ways that these populations used their roles as educational leaders to provide aid, comfort, and voice for their communities. Using these experiences, we close with some recommendations to consider the ways that leadership can help their communities during times of crisis
Maximisation of Benefits for the Poor of Investments in Renewable Electricity: A Policy Tool for Project Planning
Energy poverty is a major development issue: nearly 1.2 billion people, or close to one-fifth of the world’s population, have no access to electricity. Close to 85 per cent of them live in rural areas (Banerjee et al. 2013). After falling out of favour in the 1980s, electrification is again seen as central to poverty reduction efforts. Electricity improves users’ quality of life and can enable income generation when used for productive activities, hence supporting an escape from the poverty trap. Where generation comes from renewable sources, it also makes a positive contribution to low-carbon development; for many, this is a classic ‘win-win’ situation. This report uses the evidence collected through a comprehensive literature review to develop a policy tool to maximise the poverty impact of electrification projects. It can be of use for development and climate finance institutions funding renewable energy projects in developing countries, and keen to enhance the poverty impacts of these projects.UK Department for International Developmen
Minimum uncertainty and squeezing in diffusion processes and stochastic quantization
We show that uncertainty relations, as well as minimum uncertainty coherent and squeezed states, are structural properties for diffusion processes. Through Nelson stochastic quantization we derive the stochastic image of the quantum mechanical coherent and squeezed states
Paleo-Environment and C-14 Dating: The Key to the Depositional Age of the Tha Chang and Related Sand Pits, Northeastern Thailand
Tha Chang sand pits, Nakhon Ratchasima Province and many other sand pits in the area adjacent to the Mun River are characterized by their fluviatile environment in association with mass wasting deposits, along the paleo-river channel and the flood plain of the Mun River. Sediments of these deposits are characterized by clasts of various rock types especially the resistant ones with frequent big tree trunks, logs and wood fragments in different sizes and various stages of transformation from moldering stage to lignification and petrification. Widespread pyritization of the lower horizon suggests strongly reducing environment during burial. The Tha Chang deposits have been received much attention from geoscientists especially paleontologist communities, as they contain fragments of some distinct vertebrate species such as Stegadon sp., hominoid primate, rhinoceros Aceratherium and others. Based on the associated mammal fauna and hominoid fossils, the late Miocene ( 9 - 6 Ma) was given for the time of deposition of this sand and gravel unit. Some other reports believed that sediments and materials of these sand and gravel quarries (pits) were deposited by high-energy flood pulses contemporaneous with the tektites forming event during mid-Pleistocene at c. 0.8 Ma. Interpretation from Palynostratigraphical study suggested that the lower horizon of Tha Chang sand pit was deposited during Pliocene/Pleistocene period and the upper horizons are Pleistoncene/Holocene. It is crystal clear that all the fluviatile sediments including tektites and almost all fossil fragments being deposited in these sand pits were, likely a multiple times reworked materials. Only some old bamboo trees, some old crowling trees and fossils grasses observed on the old river bank are considered in situ. C-14 dating of 5 old wood specimens from Tha Chang Sand Pits, 15 old wood specimens from Chumpuang Sand Pits and one sample of old pottery from a Chumpuang Sand Pit were carried out in the NSF- Arizona AMS Laboratory. Although, there is no sharp boundary between the unconsolidated sedimentary horizons in the pits, C-14 ages obtained from the Tha Chang vary from 34,340 BP at the middle horizon (approx 10 m below ground zero) to >49,900 BP at the lower horizon with unknown basal formation (highly pyritized zone approx 20 - 25 m below ground zero). The ages for the Chumpuang vary from 41,700 BP, >45,900 BP and >49,900 BP from the upper most to the lower most of a broad horizon (approx 8 m to approx 12 m below ground zero). The C-14 age of the pottery collected from layer approximately 5 m below ground zero is 2,514 BP. The nature of fluviatile together with occasional mass wasting characteristics of all sand pits studies suggest the relatively faster depositional rate of the lower horizon which involved more flooding and mass wasting deposits than those of the upper horizons. The apparent of some mixing of the wood ages may indicate reworking and lag deposits nature of the area. The depositional rate of the upper most sand and soil horizon (5 m thick) is approximately 1 m per 500 years which mean both erosion and deposition had played a significant role during that time period. In term of the true age of the formation, we argue that since most of the materials deposited are reworked materials, all ages obtained from fossil fragments could not be the age of sand and gravel formation. Furthermore, the maximum age of all the tektite bearing horizons cannot be older than 0.8 Ma. The oldest C-14 age of 49,900 BP is interpreted as the minimum age of the Tha Chang and related sand pits formation when geomorphology of the area was a lot more hilly and much higher gradient than that of the present day
Q-derivatives, coherent states and squeezing
We show that the q-deformation of the Weyl-Heisenberg (q-WH) algebra naturally arises in discretized systems, coherent states, squeezed states and systems with periodic potential on the lattice. We incorporate the q-WH algebra into the theory of (entire) analytical functions, with applications to theta and Bloch functions
Static performances of timber-and bamboo-concrete composite beams: A critical review of experimental results
The use of composite beams made with traditional concrete and bio-based materials (such as timber and bamboo) is a valuable solution to reduce the environmental impact of the building sector. Timber-Concrete Composite (TCC) beams have been used for decades in structural applications such as new buildings, refurbishment of old timber structures, and bridges. Recently, different researchers suggested composite beams based on engineered bamboo, commonly named Bamboo-Concrete Composite (BCC) beams. This study presents a systematic comparison of structural performances and connection behavior of TCC and BCC beams under short-term static load. TCCs beams are compared to BCC ones using similar shear connectors. The most important aspects of the two composite systems are compared: mechanical behavior of connectors and structural behaviors of full-scale composite beams (e.g., failure modes, connection stiffness, connection shear strength, ultimate load-carrying capacity, maximum deflection and composite efficiency). This comprehensive review indicates that BCC beams have similar or even better structural performances compared with TCC
A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1
Like the CCR5 chemokine receptors of humans and rhesus macaques, the very homologous (∼98–99% identical) CCR5 of African green monkeys (AGMs) avidly binds β-chemokines and functions as a coreceptor for simian immunodeficiency viruses. However, AGM CCR5 is a weak coreceptor for tested macrophage-tropic (R5) isolates of human immunodeficiency virus type 1 (HIV-1). Correspondingly, gp120 envelope glycoproteins derived from R5 isolates of HIV-1 bind poorly to AGM CCR5. We focused on a unique extracellular amino acid substitution at the juncture of transmembrane helix 4 (TM4) and extracellular loop 2 (ECL2) (Arg for Gly at amino acid 163 (G163R)) as the likely source of the weak R5 gp120 binding and HIV-1 coreceptor properties of AGM CCR5. Accordingly, a G163R mutant of human CCR5 was severely attenuated in its ability to bind R5 gp120s and to mediate infection by R5 HIV-1 isolates. Conversely, the R163G mutant of AGM CCR5 was substantially strengthened as a coreceptor for HIV-1 and had improved R5 gp120 binding affinity relative to the wild-type AGM CCR5. These substitutions at amino acid position 163 had no effect on chemokine binding or signal transduction, suggesting the absence of structural alterations. The 2D7 monoclonal antibody has been reported to bind to ECL2 and to block HIV-1 binding and infection. Whereas 2D7 antibody binding to CCR5 was unaffected by the G163R mutation, it was prevented by a conservative ECL2 substitution (K171R), shared between rhesus and AGM CCR5s. Thus, it appears that the 2D7 antibody binds to an epitope that includes Lys-171 and may block HIV-1 infection mediated by CCR5 by occluding an HIV-1-binding site in the vicinity of Gly-163. In summary, our results identify a site for gp120 interaction that is critical for R5 isolates of HIV-1 in the central core of human CCR5, and we propose that this site collaborates with a previously identified region in the CCR5 amino terminus to enable gp120 binding and HIV-1 infections
Impact of the COVID-19 pandemic on the implementation of mobile health to improve the uptake of hydroxyurea in patients with sickle cell disease: Mixed methods study
BACKGROUND: Hydroxyurea therapy is effective for reducing complications related to sickle cell disease (SCD) and is recommended by National Health Lung and Blood Institute care guidelines. However, hydroxyurea is underutilized, and adherence is suboptimal. We wanted to test a multilevel mobile health (mHealth) intervention to increase hydroxyurea adherence among patients and improve prescribing among providers in a multicenter clinical trial. In the first 2 study sites, participants were exposed to the early phases of the COVID-19 pandemic, which included disruption to their regular SCD care.
OBJECTIVE: We aimed to describe the impact of the COVID-19 pandemic on the implementation of an mHealth behavioral intervention for improving hydroxyurea adherence among patients with SCD.
METHODS: The first 2 sites initiated enrollment 3 months prior to the start of the pandemic (November 2019 to March 2020). During implementation, site A clinics shut down for 2 months and site B clinics shut down for 9 months. We used the reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework to evaluate the implementation and effectiveness of the intervention. mHealth implementation was assessed based on patients\u27 daily app use. Adherence to hydroxyurea was calculated as the proportion of days covered (PDC) from prescription records over the first 12 and 24 weeks after implementation. A linear model examined the relationship between app usage and PDC change, adjusting for baseline PDC, lockdown duration, and site. We conducted semistructured interviews with patients, health care providers, administrators, and research staff to identify factors associated with mHealth implementation and effectiveness. We used a mixed methods approach to investigate the convergence of qualitative and quantitative findings.
RESULTS: The percentage of patients accessing the app decreased after March 15, 2020 from 86% (n=55) to 70% (n=45). The overall mean PDC increase from baseline to week 12 was 4.5% (P=.32) and to week 24 was 1.5% (P=.70). The mean PDC change was greater at site A (12 weeks: 20.9%; P=.003; 24 weeks: 16.7%; P=.01) than site B (12 weeks: -8.2%; P=.14; 24 weeks: -10.3%; P=.02). After adjustment, PDC change was 13.8% greater in those with increased app use after March 15, 2020. Interview findings indicated that site B\u27s closure during COVID-19 had a greater impact, but almost all patients reported that the InCharge Health app helped support more consistent medication use.
CONCLUSIONS: We found significant impacts of the early clinic lockdowns, which reduced implementation of the mHealth intervention and led to reduced patient adherence to hydroxyurea. However, disruptions were lower among participants who experienced shorter clinic lockdowns and were associated with higher hydroxyurea adherence. Investigation of added strategies to mitigate the effects of care interruptions during major emergencies (eg, patient coaching and health navigation) may insulate the implementation of interventions to increase medication adherence.
TRIAL REGISTRATION: ClinicalTrials.gov NCT04080167; https://clinicaltrials.gov/ct2/show/NCT04080167.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/16319
Bright Metal-Poor Stars from the Hamburg/ESO Survey. I. Selection and Follow-up Observations from 329 Fields
We present a sample of 1777 bright (9<B<14) metal-poor candidates selected
from the Hamburg/ESO Survey (HES). Despite saturation effects present in the
red portion of the HES objective-prism spectra, the data were recoverable and
quantitative selection criteria could be applied to select the sample. Analyses
of medium-resolution (~2 A) follow-up spectroscopy of the entire sample,
obtained with several 2 to 4 m class telescopes, yielded 145 new metal-poor
stars with metallicity [Fe/H]<-2.0, of which 79 have [Fe/H]<-2.5, and 17 have
[Fe/H]<-3.0. We also obtained C/Fe estimates for all these stars. From this, we
find a frequency of C-enhanced ([C/Fe]>1.0) metal-poor ([Fe/H]<-2.0) giants of
9% +- 2%, which is lower than previously reported. However, the frequency
raises to similar (>20%) and higher values with increasing distance from the
Galactic plane. Although the numbers of stars at low metallicity are falling
rapidly at the lowest metallicities, there is evidence that the fraction of
carbon-enhanced metal-poor stars is increasing rapidly as a function of
declining metallicity. For ~60 objects, high-resolution data have already been
obtained; one of these, HE 1327-2326, is the new record holder for the most
iron-deficient star known.Comment: 29 pages (emulateapj), accepted for publication in Ap
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