Parenthood, Climate Justice and the Ethics of Care: Notes Towards a Queer Analysis

This co-authored contribution takes the form of a dialogue between Carmen Dell’Aversano and Florian Mussgnug. The two discussants explore the concepts of parenthood, reproduction and care in the context of the unfolding global environmental crisis. Arguing from the perspectives of queer theory, literary studies and climate justice, they call for new strategies and attitudes towards procreation, beyond the strictures of colonizing frames of knowledge and hegemonic cultural practices. More specifically, Dell’Aversano and Mussgnug move the debate around assisted reproductive technologies in new, speculative directions that are centred on shared vulnerability and kinship, and which remain fully attentive to human and non-human relations and shared responsibilities on a warming planet

Ovatoxin-a, a palytoxin analogue isolated from Ostreopsis cf. ovata Fukuyo: cytotoxic activity and ELISA detection

This study provides the first evaluation of the cytotoxic effects of the recently identified palytoxin (PLTX) analog, ovatoxin-a (OVTX-a), the major toxin produced by Ostreopsis cf. ovata in the Mediterranean Sea. Its increasing detection during Ostreopsis blooms and in seafood highlights the need to characterize its toxic effects and to set up appropriate detection methods. OVTX-a is about 100 fold less potent than PLTX in reducing HaCaT cells viability (EC50 = 1.1 7 10 129 M vs 1.8 7 10 1211 M, MTT test) in agreement with a reduced binding affinity (Kd = 1.2 7 10 129 vs 2.7 7 10 1211 M, saturation experiments on intact cells). Similarly, OVTX-a hemolytic effect is lower than that of the reference PLTX compound. Ost-D shows the lowest cytotoxicity toward HaCaT keratinocytes, suggesting the lack of a hydroxyl group at C44 as a critical feature for PLTXs cytotoxic effects. A sandwich ELISA developed for PLTX detects also OVTX-a in a sensitive (LOD = 4.2 and LOQ = 5.6 ng/mL) and accurate manner (Bias = 0.3%), also in O. cf. ovata extracts and contaminated mussels. Although in vitro OVTXa appears less toxic than PLTX, its cytotoxicity at nanomolar concentrations after short exposure time rises some concern for human health. The sandwich ELISA can be a viable screening method for OVTXs detection in monitoring program

The Queerest Crossing: Questioning the Human-Animal Divide

The aim of this paper is to extend the definition and the relevance, both intellectual and political, of queer through a systematic questioning of one of the most basic and most pervasive identitarian assumptions current in all human societies: that of the “natural” divide between humans and animals