Role of iron sucrose infusion in correction of iron deficiency anemia during pregnancy

Background: Iron deficiency anemia (IDA), is defined as decrease in the amount of red blood cells (RBCs) or hemoglobin in the blood due to insufficient iron in the body. We carried out this study to measure the efficacy of iron sucrose in iron deficiency anemia in pregnant women.Methods: In our prospective study 100 patients were included. All of them were having USG maturity between 15-34 weeks. All of them were given iron sucrose IV according to their requirements and follow-up was taken after 4 weeks by measuring Hb level.Results: Hb level improved significantly (2.1 grams) within a short duration of interval. 14% patients suffered from minor side effects.Conclusions: Iron sucrose has been found very useful for correction of iron deficiency anemia in antenatal patients

Chemoterapy of tuberculosis

This article does not have an abstract

Indications and trends of caesarean birth delivery in the current practice scenario

Background: Objective of current study was to analyze incidence, indications and trends of cesarean birth delivery in our environment.Methods: A prospective study of the cesarean sections performed at V.S. general teaching hospital in Ahmedabad from January 2008 to December 2013Results: Out of 28,411 total deliveries, 11629 women underwent CS. Each year the CS rate, above 40%, was relatively constant. 72.46% patients were within 20-29 years of age group. 39% patients were from middle to higher socio-economic class. CS in emergency patient was consistently more than 50% and in registered patient around 40%. Maternal indications for CS were twice common to fetal indications. Previous CS and fetal distress were the commonest among maternal and fetal indications respectively. Overall maternal morbidity in CS ranged from 8-10%, commonest being blood transfusion and wound infection. Neonatal morbidity was less than half and neonatal mortality was almost one third in comparison to normal delivery. Rising CS trend was noted in patients with previous CS, fetal distress, oligohydramnios and failed induction. Gradual but constant decline in CS rate was noted among emergency patients, patient with CPD, obstructed labor and PROM.Conclusions: Although to some extent higher CS rate is justifiable due to remarkable reduction in neonatal mortality and morbidity in high risk patients; the CS rate in our environment is still three times higher than WHO recommendation. In controlled environment with experienced staff, careful selection of patients for normal delivery among patients with previous CS, breech presentation and scientific induction of labor may satisfy our concern for mother and newborn safety while keeping the CS rate low

Chemotherapy of bacterial infections. Part VIII. Synthesis of carboxylic acid derivatives of 2-sulphanilamidothiazole

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A study of effectiveness of injection Depot medroxyprogesterone in postpartum women

Background: Depot medroxyprogesterone (DMPA) injection 150 mg intramuscular was used in postpartum women for contraception in this study, once every 3 months. The aim of the study acceptance and compliance of DMPA, observe side effects related to usage of DMPA and establish its effectiveness as a postpartum contraception method.Methods: This is a prospective study carried out at Obstetrics and Gynaecology department over a period of 9 months and follow up was done. Only patients of full term normal delivery and Lower segment caesarean section (LSCS) were included. They were counselled properly and after their willingness for enrolment they were included in study after taken consent.Results: Out of 50 cases selected maximum patients, 48% were in the age group of 26 to 30, 38% were from lower socioeconomic class. Amenorrhoea and irregular spotting were found in 68% and 42%respectively. There was no case of failure of this contraceptive method in this study.Conclusions: DMPA is an effective and safe method of contraception in lactating period. Proper counselling will increase acceptance of DMPA. Awareness in patients regarding its benefits as compared to other contraceptive methods.

Role of doppler in fetal growth restriction

Background: Fetal growth restriction is an important and particularly challenging problem for modern obstetricians and paediatricians. The present study is to correlate the importance of Doppler velocimetry and perinatal outcome in cases of growth restricted foetuses by comparing perinatal outcome of control & study groups with normal and abnormal Doppler waveforms.Methods: A study and a control group comprising of 50 pregnant women having growth restricted foetuses in each group was matched for all other confounding factors except for Doppler changes. These patients were followed up and the perinatal outcomes of FGR foetuses having Doppler changes was compared with those having normal Doppler studies.Results: In our study, alteration in both MCA and UmbA Doppler was associated with perinatal morbidity and NICU admissions in 64% and mortality in 28%. Doppler changes showing altered CPR less than 1 had adverse outcome with NICU admission in 61% and mortality in 34%. Alteration in DV Doppler was associated with perinatal morbidity and NICU admissions in 17% cases and mortality in 83% cases, with no pregnancies having a healthy outcome. Among high-risk pregnancies with suspected IUGR, the use of Doppler assessment significantly decreases the likelihood of labor induction, caesarean delivery, and perinatal deaths.Conclusions: Abnormal Doppler waveform changes indicate adverse perinatal outcome of pregnancies with FGR. Doppler study helps to reduce perinatal mortality and morbidity by timely and appropriate interventions

Study of Gross Congenital Anomalies in the Tertiary Care Hospital

Introduction: Congenital anomaly is a structural or functional defect that occurs during intrauterine life and can beidentified prenatally,at birth or sometimelater in infancy. Congenital anomalies may be caused by genetic or environmental factors. Most congenital anomalies, however, show the familial patterns expected of multi-factorial inheritance. Methods:Cross sectional observational hospital based study conducted during the period of august 2020 to august 2021.All new-borns delivered in the hospital with congenital anomalies were included in study. Relevant information regarding maternal age, parity, gestational age, sex and the outcome were documented. Results: Incidence of congenital anomalies are more associated with increasing maternal and paternal age. Higher incidence was found in higher order pregnancy. Maximum cases of congenital anomalies affected musculoskeletal system followed by gastrointestinal system and genitourinary system. Conclusion: With the help of proper antenatal screening,diagnostic modalities and better health care facilities, congenital anomalies can be diagnosed earlier and interventions planned accordingly. Morethan one risk factors can be linked with congenital anomalies. Earlier Central nervous system anomaly was commonly involved but increase folate supplementation in target population reducing the incidence

2-N<SUP>1</SUP>-sulphanilamido-4-n-propylthiazole

This article does not have an abstract

Chemotherapy of bacterial infections Part V. Synthesis of 2-N<SUP>1</SUP>-sulphanilamido-5-alkyl and 2-N<SUP>1</SUP>-sulphanilamido-4-methyl-5-alkyl-thiazoles

This article does not have an abstract

Chemotherapy of tuberculosis Part I. Synthesis of possible lipophilic chemotherapeuticals of the sulphonamide and sulphone series derived from fatty acids, including those of the chaulmoogra group

This article does not have an abstract