Planeamiento estratégico de la agricultura en la Región Ancash

Siguiendo la metodología del proceso estratégico, que ha sido creada por D’Alessio (2015), se elaboró el presente planeamiento estratégico para la agricultura en la región Ancash. De acuerdo con ello, se continuará produciendo y exportando los principales productos, que son espárragos, palta y alfalfa; pero con tecnología y mano de obra calificada. Esto generará más productividad y rentabilidad. Así, para el año 2027, el sector ocupará el tercer lugar a nivel nacional, con alta productividad y valor agregado; exportará diversos productos y operará de manera sostenible con el fin de promover el desarrollo económico de la población. Dicho escenario se encuentra alineado con objetivos de largo plazo, como aumentar la superficie agrícola y las hectáreas con sistema de riego. Para alcanzar esta visión y sus respectivos objetivos, se implementarán las siguientes estrategias intensivas, que fueron seleccionadas mediante un análisis profundo: (a) desarrollar el mercado asiático de paltas, (b) penetrar el mercado de alfalfa en los Estados Unidos, (c) penetrar el mercado nacional con diversos productos, (d) desarrollar la producción y comercialización de yuca, oca y olluco; (e) desarrollar productos manufacturados de palta, (f) desarrollar conservas de espárragos, (g) desarrollar papas congeladas, listas para freír; y (h) desarrollar productos manufacturados de alimentos balanceados para animales a partir de maíz amarillo duroThis strategic planning for the agriculture in the Ancash region has been created based on the Strategic Process methodology, developed by D'Alessio (2015). The sector will continue to produce and export its main goods, which are asparagus, avocado and alfalfa, but with technology and skilled labor, generating more productivity and profitability. By the year 2027, the sector will own the third place at the national level, with high productivity and added value, exporting diverse products and operating in a sustainable way to promote the economic development of the population. This is in line with long-term objectives such as increasing the agricultural area and the hectares with irrigation system. In order to achieve this vision and its respective objectives, intensive strategies will be implemented, which were selected through in-depth analysis: (a) developing the Asian avocado market, (b) penetrate the alfalfa market in the United States, (c) penetrate the national market with various products, (d) to develop the production and marketing of cassava, oca and olluco; (e) developing avocado products, (f) developing preserved asparagus, (g) develop frozen, readyto- fry potatoes; and (h) developing processed animal feed products from hard yellow maizeTesi

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Análisis comparativo entre los modelos de madurez reconocidos en la gestión de proyectos

Este trabajo de grado identifica y analiza los principales criterios comparativos entre los modelos de madurez reconocidos en la gestión de proyectos. Fue un estudio de tipo descriptivo con un enfoque cuantitativo. La información común existente acerca de los modelos de madurez para la gestión de proyectos, se recolectó, clasificó y analizó de tal manera que se pudieron identificar los principales criterios comparativos y realizar un análisis de cada uno. La investigación encontró que los niveles de madurez presentes en cada uno de los modelos analizados, son muy similares en cuanto a cantidad y características. De igual manera permitió reconocer que el criterio de certificaciones es determinante en los modelos de madurez, ya que es una de las prácticas más comunes y frecuentes de hoy en día, tanto a nivel profesional como de organización Finalmente, esta investigación permitió concluir que modelo OPM3 se puede reconocer como el modelo más reconocido a nivel de industria y a nivel de comunida

Tensile Strength of Poly(lactic acid)/Bleached Short Hemp Fiber Fully Green Composites as Replacement for Polypropylene/Glass Fiber

The compatibility between poly(lactic acid) (PLA) and natural fibers to develop bio-sourced, recyclable, and biodegradable composites remains a commonplace issue. This work highlights that, at least in the case of hemp, pulping and bleaching towards delignified short fibers attained remarkable improvements over untreated hemp strands. This approach differs from usual proposals of chemically modifying hydroxyl groups. Soda-bleached hemp fibers (SBHFs) granted a relatively large bonding surface area and a satisfactory quality of the interphase, even in the absence of any dispersant or compatibilizer. To attain satisfactory dispersion, the matrix and the fibers were subjected to kinetic mixing and to a moderately intensified extrusion process. Then, dog-bone specimens were prepared by injection molding. Up to a fiber content of 30 wt.%, the tensile strength increased linearly with the volume fraction of the dispersed phase. It reached a maximum value of 77.8 MPa, signifying a relative enhancement of about 52%. In comparison, the tensile strength for PLA/hemp strands was 55.7 MPa. Thence, based on the modified rule of mixtures and the Kelly & Tyson modified equation, we analyzed this performance at the level of the constituent materials. The interfacial shear strength (over 28 MPa) and other micromechanical parameters were computed. Overall, this biocomposite was found to outperform a polypropylene/sized glass fiber composite (without coupling agent) in terms of tensile strength, while fulfilling the principles of green chemistry