Targeted testing for acute HIV infection in North Carolina

Persons with acute HIV infection contribute disproportionately to HIV transmission. Identification of these persons is a critical public health challenge. We developed targeted approaches to detect HIV RNA in persons with negative serological tests

Progression of a large syphilis outbreak in rural North Carolina through space and time: Application of a Bayesian Maximum Entropy graphical user interface

In 2001, the primary and secondary syphilis incidence rate in rural Columbus County, North Carolina was the highest in the nation. To understand the development of syphilis outbreaks in rural areas, we developed and used the Bayesian Maximum Entropy Graphical User Interface (BMEGUI) to map syphilis incidence rates from 1999–2004 in seven adjacent counties in North Carolina. Using BMEGUI, incidence rate maps were constructed for two aggregation scales (ZIP code and census tract) with two approaches (Poisson and simple kriging). The BME maps revealed the outbreak was initially localized in Robeson County and possibly connected to more urban endemic cases in adjacent Cumberland County. The outbreak spread to rural Columbus County in a leapfrog pattern with the subsequent development of a visible low incidence spatial corridor linking Roberson County with the rural areas of Columbus County. Though the data are from the early 2000s, they remain pertinent, as the combination of spatial data with the extensive sexual network analyses, particularly in rural areas gives thorough insights which have not been replicated in the past two decades. These observations support an important role for the connection of micropolitan areas with neighboring rural areas in the spread of syphilis. Public health interventions focusing on urban and micropolitan areas may effectively limit syphilis indirectly in nearby rural areas

Direct ionization and electron capture in M-shell x-ray production by fluorine ions

This article discusses direct ionization and electron capture in M-shell x-ray production by fluorine ions

Handbook Research Design and Social Measurement

ix.518 hal.;26 c

Handbook of research design and social measurement

x,518hlm.;bib.;tab.;indek

Handbook of research design and social measurement, 4th ed./ Miller

xvi, 678.: tab.; 25 c

Handbook of research design and social measurement, 4th ed./ Miller

xvi, 678 hal..; 25 cm

Handbook of research design and measurement

x, 514 p.; 23 cm