20 research outputs found
The weight lowering effect of sibutramine and its impact on serum lipids in cardiovascular high risk patients with and without type 2 diabetes mellitus - an analysis from the SCOUT lead-in period
- Author
- Arya M Sharma
- B Schieffer
- Bente Brendorp
- C Torp-Pedersen
- CA Dujovne
- Charlotte Andersson
- Christian Torp-Pedersen
- CM Ballantyne
- CS Fox
- D DeFaria Yeh
- DW Haslam
- EJ Brunner
- Emil L Fosbøl
- G De Backer
- G Yuan
- I Graham
- Ian D Caterson
- J Jeppesen
- J Liu
- KM Flegal
- Lars Køber
- M Halle
- M Mauro
- M Shechter
- N Finer
- Nick Finer
- P Poirier
- Peter Weeke
- Philip T James
- PW Wilson
- Richard A Rode
- RP Bogers
- RR Holman
- WP James
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
- A Campbell
- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
- A Doms
- A Donovan
- A Donovan
- A Dávalos
- A Gaeta
- A Garny
- A Gnjec
- A Gomes
- A Gopalakrishnan
- A Hald
- A Henney
- A Hirayama
- A Hoffmann
- A Huber
- A Hugman
- A Iannetti
- A Ide-Ektessabi
- A Jacobs
- A Jeyabalan
- A Kahvejian
- A Karrar
- A Kasztler
- A Kibel
- A Kocyigit
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- A Kumral
- A Lass
- A Lecube
- A Lewén
- A Lotery
- A Maggio
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- A Matsuzawa
- A Mitra
- A Monge
- A Murakami
- A Murakami
- A Murakami
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- A Persson
- A Pietrangelo
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- A Post
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- A Rattner
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- A Saltelli
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- A Sassano
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- A Scalbert
- A Scalbert
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- A Szewczyk
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- A Tedgui
- A Terman
- A Terman
- A Terman
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- A Virdis
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- A Wagner
- A Wagner
- A Wagner
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- Ad hoc committee on systemic lupus erythematosus response criteria for fatigue
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- Z Pei
- Z Serdar
- Z Tong
- Z Tong
- Z Yu
- Z Zhang
- ZD Liu
- ZD Liu
- ZE Karanjawala
- ZE Suntres
- ZI Cabantchik
- ZZ Chong
- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
PET Imaging Reveals Early Pulmonary Perfusion Abnormalities in HIV Infection Similar to Smoking
- Author
- Publication venue
- 'Society of Nuclear Medicine'
- Publication date
- Field of study
Laser Directed Growth of Carbon-Based Nanostructures by Plasmon Resonant Chemical Vapor Deposition
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- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Surface Enhanced Raman Spectroscopy of Organic Molecules on Magnetite (Fe 3
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- Publication venue
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- Publication date
- Field of study
Synthesis of Stoichiometric FeS 2
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- Altermatt P. P.
- Bausch S.
- Berry N.
- Bi Y.
- Bukhtiyarova G. A.
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- Colin A. Wolden
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- Wadia C.
- Wolden C. A.
- Yu L.
- Zhong X. H.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Shape-controlled synthesis of single-crystalline Fe2O 3 hollow nanocrystals and their tunable optical properties
- Author
- Alivisatos A. P.
- Ando M.
- Chen J.
- Chen T. Y.
- Chen X. Y.
- Cherepy N. J.
- Chernyshova I. V.
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- deFaria D. L. A.
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- Hashimoto T.
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- Hu X. L.
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- Iijima S.
- Jia C. J.
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- Peng X. G.
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- Sherman M. D.
- Soga D.
- Sun Z. Y.
- Tsuda N.
- Vayssieres L.
- Wang G. X.
- Wang Y.
- Wang Z. K.
- Xiong Y. J.
- Yang C. C.
- Zheng Z.
- Zhong L. S.
- Zhou H. S.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- 04/06/2009
- Field of study
10.1021/jp9020883Journal of Physical Chemistry C113229928-993
Congenital heart disease in the ESC EORP Registry of Pregnancy and Cardiac disease (ROPAC)
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- Abd-El Aziz M. Gamal
- Abdilaahi A.A.
- Abilova S.
- Adamson D.
- Ahamed N.
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- Ahmed C.M.
- Ain Al
- Akbar R.
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- Ali L. Ait
- Ali M.
- Almahmeed W.A.R.
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- Ang H.L.
- Ansari-Ramandi M.M.
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- Aprami T.M.
- Aquieri A.
- Arrigo M.
- Arstall M
- Arstall Margaret
- Ashour Z.
- Askar A.O.
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- 'Elsevier BV'
- Publication date
- 01/05/2021
- Field of study
Phase Transformation and Charge Transfer in Heavily Iron Ion Doped Titanium Oxide and Oxynitride Nanocolloids
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- Anpo M.
- Asahi R.
- Baodong Mao
- Becke A. D.
- Brevet A.
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- James L. Gole
- Jonathan Brauer
- Junwei Wang
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- Lixia Sang
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- 'American Chemical Society (ACS)'
- Publication date
- Field of study