2,521 research outputs found

    Peeling Back the Onion Competitive Advantage Through People: Test of a Causal Model

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    Proponents of the resource-based view (RBV) of the firm have identified human resource management (HRM) and human capital as organizational resources that can contribute to sustainable competitive success. A number of empirical studies have documented the relationship between systems of human resource policies and practices and firm performance. The mechanisms by which HRM leads to firm performance, however, remain largely unexplored. In this study, we explore the pathways leading from HRM to firm performance. Specifically, we use structural equation modeling to test a model positing a set of causal relationships between high performance work systems (HPWS), employee retention, workforce productivity and firm market value. Within a set of manufacturing firms, results indicate the primary impact of HPWS on productivity and market value is through its influence on employee retention

    HRM and Firm Productivity: Does Industry Matter?

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    Recent years have witnessed burgeoning interest in the degree to which human resource systems contribute to organizational effectiveness. We argue that extant research has not fully considered important contextual conditions which moderate the efficacy of these practices. Specifically, we invoke a contingency perspective in proposing that industry characteristics affect the relative importance and value of high performance work practices (HPWPs). We test this proposition on a sample of non-diversified manufacturing firms. After controlling for the influence of a number of other factors, study findings support the argument that industry characteristics moderate the influence of HPWPs on firm productivity. Specifically, the impact of a system of HPWPs on firm productivity is significantly influenced by the industry conditions of capital intensity, growth and differentiation

    Non-perturbative corrections to mean-field behavior: spherical model on spider-web graph

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    We consider the spherical model on a spider-web graph. This graph is effectively infinite-dimensional, similar to the Bethe lattice, but has loops. We show that these lead to non-trivial corrections to the simple mean-field behavior. We first determine all normal modes of the coupled springs problem on this graph, using its large symmetry group. In the thermodynamic limit, the spectrum is a set of δ\delta-functions, and all the modes are localized. The fractional number of modes with frequency less than ω\omega varies as exp(C/ω)\exp (-C/\omega) for ω\omega tending to zero, where CC is a constant. For an unbiased random walk on the vertices of this graph, this implies that the probability of return to the origin at time tt varies as exp(Ct1/3)\exp(- C' t^{1/3}), for large tt, where CC' is a constant. For the spherical model, we show that while the critical exponents take the values expected from the mean-field theory, the free-energy per site at temperature TT, near and above the critical temperature TcT_c, also has an essential singularity of the type exp[K(TTc)1/2]\exp[ -K {(T - T_c)}^{-1/2}].Comment: substantially revised, a section adde

    Pseudo cholinesterase-diagnostic and prognostic value in organophosphorus poisoning

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    Background: Organophosphorus compound poisoning is a common clinical situation encountered in emergency department. The estimation of pseudo cholinesterase levels in plasma help to identify OP poisoning. Aim of this study was the levels of pseudo cholinesterase in plasma as a diagnostic aid in patients with suspected organophosphorus poisoning and to predict the prognosis and mortality based on pseudo cholinesterase activity.Methods: 390 cases of suspected organophosphorus compound poisoning were selected above 18 years of age. Detailed history and clinical examination were done. The serum levels of enzyme pseudo cholinesterase were estimated on 1st and 3rd and 6th day.Results: 61% were males, 39% were females. Age range 18-55 years. Most of the patients were admitted within 4 hours of consumption. 50% cases were mild, 26% were moderate and 24% were severe cases, Commonest clinical features were vomiting, diarrhea and abdominal cramps. Common signs were miosis (46%), difficulty in breathing (42%), cold calmmy skin, bradycardia. Patients who survived had raising values of enzyme levels and in patients who expired did not show much increase in enzyme values.Conclusions: In initial stages of poisoning, determining pseudo cholinesterase activity forms a reliable test. In patients who survived had values above 4300 U/L and showed increasing levels on successive days indicating better prognosis. Low values of enzymes in initial stages of poisoning as well as decreasing values on the third day indicate increased mortality

    A multiattribute utility evaluation of different methods for the detection of enteric protozoa causing diarrhea in AIDS patients

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    <p>Abstract</p> <p>Background</p> <p>Enteric protozoa and sporozoa have emerged as important opportunistic parasites and can cause fatal infections in AIDS patients. The line of treatment being different for them necessitates an accurate and prompt identification of these to avoid empirical treatment. In this study which is the first of its kind from India we did a comprehensive evaluation of different techniques, comparing them on the basis of the attributes like yield, cost, time taken, expertise and infrastructure. For the first time combination of Calcoflour White and DAPI, a nuclear stain, were used to identify <it>Microsporidia </it>spp. Thus, a diagnostic protocol was devised for rapid, sensitive and cost effective identification of the opportunistic enteric protozoa.</p> <p>Results</p> <p>The organisms isolated from the stool samples of the cases (450 HIV patients) were predominantly <it>Cryptosporidium </it>spp., <it>Microsporidia </it>spp. and <it>Cyclospora </it>spp. Interestingly, the control group (200 relatives of the patients who were HIV negative) showed a high incidence (21%) of <it>Cryptosporidium </it>spp. We found a significant increase in the sensitivity of microscopy in detecting <it>Cryptosporidium </it>spp. and <it>Cyclospora </it>spp. after formol ether concentration. Kinyoun's staining was better compared to Modified safranin staining for <it>Cryptosporidium </it>spp. identification. Although ELISA had a sensitivity of 93.25% and specificity of 97% for <it>Cryptosporidium </it>spp. detection, we ranked Kinyoun's staining better than ELISA because it is not affordable to most of our patients. For detecting <it>Cyclospora cayetanensis</it>, autoflourescence was the easiest and most cost effective method followed by Safranin technique. Combination of Calcoflour White stain and DAPI gave good results for the identification of <it>Microsporidia </it>spp. We assessed the above techniques and graded the attributes in the following descending order: cost effectiveness, sensitivity, ease of use and interpretation, time taken for the procedure and batch testing.</p> <p>Conclusion</p> <p>Thus, we conclude that a combination of minimum three procedures should be carried out for the screening of stool specimens of HIV positive patients. Kinyoun's staining should be made mandatory for every diarrheal stool sample from HIV patients. Also every laboratory should assign its own value to the attributes and apply Multiattribute utility theory or the Analytical hierarchy process to decide the most appropriate methodology.</p
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