1,253 research outputs found

    Assessing nature-based solutions uptake in a Mediterranean climate: Insights from the case-study of Malta

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    Nature-based solutions are increasingly promoted in regional and national policies because of their potential to contribute toward multiple Sustainable Development Goals (SDG) and promote resilient responses to climate change. However, several barriers continue to limit the effective implementation of NbS at local scales and hinder uptake by practitioners and businesses. This research analyses a database of 96 NbS implemented in Malta and a Mediterranean climate, compares local implementation with regional case-studies from a similar climate and, through interviews with stakeholders from the case-study area of Malta, identifies strengths, weaknesses, opportunities, and threats (SWOT) of current NbS implementation and assesses enablers and barriers to NbS uptake. Most NbS case-studies addressed biodiversity loss, climate action, health and wellbeing, and sustainable cities and communities. NbS were associated with multiple arising benefits but social and economic benefits, such as green job creation, social cohesion and ownership by communities, were less often identified in the analysed case-studies. Alignment with policies, arising public relations benefits from NbS implementation, the adoption of interdisciplinary approaches involving multiple stakeholders, and the availability of regional guidelines were identified by the interviewees as key enablers supporting local implementation. Multiple institutional, infrastructural and perception barriers continue to limit participation, ownership, integration of NbS in planning and governance, and uptake by businesses. Based on these observations, we identify the need to consider NbS as a means to address societal challenges faced by communities and therefore their involvement, and that of practitioners working across disciplines needs to be established early on in NbS co-design processes. We argue that experimentation is critical to address gaps in knowledge, and develop collaborations that permit the development of context-specific NbS which, in addition to considering the ecological and technological conditions in decisions relating to NbS siting and design, also reflect the perceptions and needs of communities

    MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication

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    Modern maize was domesticated from Teosinte parviglumis, with subsequent introgressions from Teosinte mexicana, yielding increased kernel row number, loss of the hard fruit case and dissociation from the cob upon maturity, as well as fewer tillers. Molecular approaches have identified several transcription factors involved in the development of these traits, yet revealed that a complex regulatory network is at play. MaizeCODE deploys ENCODE strategies to catalog regulatory regions in the maize genome, generating histone modification and transcription factor ChIP-seq in parallel with transcriptomics datasets in 5 tissues of 3 inbred lines which span the phenotypic diversity of maize, as well as the teosinte inbred TIL11. Integrated analysis of these datasets resulted in the identification of a comprehensive set of regulatory regions in each inbred, and notably of distal enhancers which were differentiated from gene bodies by their lack of H3K4me1. Many of these distal enhancers expressed non- coding enhancer RNAs bi-directionally, reminiscent of “super enhancers” in animal genomes. We show that pollen grains are the most differentiated tissue at the transcriptomic level, and share features with endosperm that may be related to McClintock’s chromosome breakage- fusion-bridge cycle. Conversely, ears have the least conservation between maize and teosinte, both in gene expression and within regulatory regions, reflecting conspicuous morphological differences selected during domestication. The identification of molecular signatures of domestication in transcriptional regulatory regions provides a framework for directed breeding strategies in maize.This preprint is made available through bioRxiv at doi:https://doi.org/10.1101/2024.02.22.581585. Copyright 2024, The Authors. It is made available under a CC-BY 4.0 International license

    Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

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    Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente

    Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

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    This paper presents measurements of the W+→Ό+ÎœW^+ \rightarrow \mu^+\nu and W−→Ό−ΜW^- \rightarrow \mu^-\nu cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13

    Search for chargino-neutralino production with mass splittings near the electroweak scale in three-lepton final states in √s=13 TeV pp collisions with the ATLAS detector

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    A search for supersymmetry through the pair production of electroweakinos with mass splittings near the electroweak scale and decaying via on-shell W and Z bosons is presented for a three-lepton final state. The analyzed proton-proton collision data taken at a center-of-mass energy of √s=13  TeV were collected between 2015 and 2018 by the ATLAS experiment at the Large Hadron Collider, corresponding to an integrated luminosity of 139  fb−1. A search, emulating the recursive jigsaw reconstruction technique with easily reproducible laboratory-frame variables, is performed. The two excesses observed in the 2015–2016 data recursive jigsaw analysis in the low-mass three-lepton phase space are reproduced. Results with the full data set are in agreement with the Standard Model expectations. They are interpreted to set exclusion limits at the 95% confidence level on simplified models of chargino-neutralino pair production for masses up to 345 GeV

    Search for direct stau production in events with two hadronic tau-leptons in root s=13 TeV pp collisions with the ATLAS detector

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    A search for the direct production of the supersymmetric partners ofτ-leptons (staus) in final stateswith two hadronically decayingτ-leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of139fb−1, recorded with the ATLAS detector at the LargeHadron Collider at a center-of-mass energy of 13 TeV. No significant deviation from the expected StandardModel background is observed. Limits are derived in scenarios of direct production of stau pairs with eachstau decaying into the stable lightest neutralino and oneτ-lepton in simplified models where the two staumass eigenstates are degenerate. Stau masses from 120 GeV to 390 GeV are excluded at 95% confidencelevel for a massless lightest neutralino

    Hard Tissue Applications of Biocomposites

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    Composites were first used clinically in the 1970s, these were based on carbon reinforced epoxy resin and although they progressed to successful clinical applications, none remained in use much beyond their initial clinical trials. The major problems were either the inability to shape the implant to fit the patient, or the method of manufacture being expensive and complex, finally these materials were “first generation” biomedical composites being bioinert. In the 1980s the second generation, that is bioactive composites, were developed and brought into clinical trial. As surgeons have been able to shape these implants to fit their patients the application of these materials has been more successful and being bioactive have lead to stronger bonds between the implant and the supporting bone, thus the implants has progressed to clinical use after their initial clinical trials. However, most of these could only be used in low load bearing applications. Since the early 2000s and the first edition of this book, the number of composite implants in clinical application and the loads to which they are exposed have both increased substantially. Improvements have come from applying engineering composites technologies to increase the mechanical properties and the use of bioactive components and the release of bioactive molecules to increase the bioactivity of the materials and devices

    Measurement of the t¯tZ and t¯tW cross sections in proton-proton collisions at √s=13 TeV with the ATLAS detector

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    A measurement of the associated production of a top-quark pair (tÂŻt) with a vector boson (W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV is presented, using 36.1  fb−1 of integrated luminosity collected by the ATLAS detector at the Large Hadron Collider. Events are selected in channels with two same- or opposite-sign leptons (electrons or muons), three leptons or four leptons, and each channel is further divided into multiple regions to maximize the sensitivity of the measurement. The tÂŻtZ and tÂŻtW production cross sections are simultaneously measured using a combined fit to all regions. The best-fit values of the production cross sections are σtÂŻtZ=0.95±0.08stat±0.10syst pb and σtÂŻtW=0.87±0.13stat±0.14syst pb in agreement with the Standard Model predictions. The measurement of the tÂŻtZ cross section is used to set constraints on effective field theory operators which modify the tÂŻtZ vertex
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