Distribution of ventilation-perfusion ratios in pneumonectomized dogs

In this paper, the distribution of ventilation (VA) and of pulmonary perfusion (Q), gas exchanges, and the single breath CO diffusing capacity are measured in 8 dogs before and after left pneumonectomy. During surgery 4 dogs, in which the left pulmonary artery is clamped, and 4 other dogs in which the left mainstem bronchus is clamped, are studied. A minute ventilation (VE) is adjusted during the initial stage study in each dog but it is kept constant for the other stages. For the entire group of dogs, the overall VE/Q varies from 0.8 to 3.0 in the baseline study. In the inital stage study, the perfusion distribution is unimodal and the ventilation distribution is unimodal or bimodal. The percentage of ventilation of the second mode correlates approximately with the overall VA/Q. After clamping the left pulmonary artery, the correlation between overall VA/Q, capillary shunt, and blood gases data is excellent and the ventilation and perfusion distributions are both bimodal. One perfusion mode is situated in the low VA/Q ratios while one ventilation mode is situated in the high VA/Q ratios. After clamping the left mainstem bronchus, the average anatomical shunt is 27%, the ventilation and perfusion are both bimodal, and the mean PaO2 is 55 mm Hg. Ultimately the ventilation and perfusion distributions tend to return to normal after pneumonectomy.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Le service de chirurgie thoracique

info:eu-repo/semantics/publishe

Ventilation in dogs on cardiopulmonary bypass with and without lungs

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Combined heart-lung transplantation for terminal pulmonary lymphangioleiomyomatosis

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Lack of effect of somatostatin and analogues in lymphorrhagia from ruptured thoracic duct [10]

SCOPUS: le.jinfo:eu-repo/semantics/publishe

UTILISATION D'OXYGENATEURS A MEMBRANE TYPE LANDE EDWARDS COMME POUMONS ARTIFICIELS

Lande Edwards membrane oxygenators were tested as artificial lungs in 6 dogs: the right heart directly perfused the oxygenators during apnea lasting 1 hour. During such a pulmonary by pass, right ventricular pressure doubled in comparison with initial values, with a moderate decrease in cardiac output; mean PO2 rose from 40 to 67 mm Hg and PCO2 decreased from 54 to 49 mm Hg through the oxygenator.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

LESIONS IATROGENES DANS UNE SERIE DE 1.250 MEDIASTINOSCOPIES CERVICALES

Forty seven complications occurred as a consequence of 1,250 mediastinoscopies, a rate of 3.8%. There were 17 hemorrhages, 7 of which necessitated thoracotomy. One of these died of laceration of the pulmonary artery. Mediastinoscopy was a factor in the death of 6 other patients.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

Volume of the graft and the native lung after single-lung transplantation for emphysema

info:eu-repo/semantics/publishe

Continuous spirometry for detection of double-lumen endobronchial tube displacement

Flow-volume and pressure-volume loops were measured with continuous spirometry in 49 patients in whom the trachea was intubated 'blindly' with a double-lumen endobronchial tube for thoracic surgery. Nineteen endobronchial tubes were malpositioned by fibreoptic bronchoscopic criteria; 63% of these were suspected because of the configuration of the spirometric loops. During positioning of the patient and during operation, 34.7% of the endobronchial tubes migrated from the initially correct or corrected position. The secondary displacements were identified by abnormal loop configurations and confirmed with fibreoptic bronchoscopy. Continuous spirometric monitoring is helpful in detecting endobronchial tube displacement during intubation and surgery.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Lande Edwards membrane oxygenator without pump as total lung prosthesis

Fourteen anesthetized dogs remained in apnea for 1 to 4 hr on total extracorporeal breathing through a Lande Edwards membrane oxygenator (LEMO). The LEMO was directly perfused by the right heart in total pulmonary bypass, without a pump or reservoir, as an external artificial lung. A 2 sq. M. LEMO proved adequate for a dog weighing 10 kg. Pulmonary arterial pressure increased 60% of the base line value at the start of bypass because of transitory LEMO resistance, three times the normal pulmonary resistance; the pressure then returned to the initial value. Systemic arterial pressure dropped to 61% on bypass. The heart did not fail. Cardiac output, central venous pressure and the electrocardiogram remained unchanged. P(O2) at the LEMO outlet was more than 200 mm Hg. Oxygen transfer was less than 20 ml per min per square m because of hemodilution and hypothermia. Dogs survived if bypass was arrested after 1 hr; if not, they died after an average of 3 hr, 20 min on bypass.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe