3 research outputs found
Trans-Oral Vertical Gastroplasty As a Viable Treatment for Childhood Obesity - A Study of 21 Adolescents with Up to 18 Months of Follow-Up
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Clinical experience of transoral suturing for an endoluminal vertical gastroplasty: 1-year follow-up in 64 patients
Bariatric surgery for severe obesity has demonstrated significant health benefits, but it is not without complications. Transoral approaches to weight loss offer a minimally invasive option.
To evaluate the safety and feasibility of a transoral suturing procedure for weight loss.
Single-center, uncontrolled study with a 1-year follow-up.
Hospital de Clinicas, Caracas, Venezuela.
Sixty-four patients (mean age [SD] 31.5 +/- 10.1 years, range 16-62 years; mean (SD) preoperative body mass index [BMI] 39.9 +/- 5.1 kg/m(2), range 28.0-60.2 kg/m(2)) were enrolled between 2003 and 2005.
Endoluminal vertical gastroplasty by using a continuous suture pattern to treat obesity.
Short-term complication monitoring and patient weight before the procedure and at 1, 3, and 12 months after the procedure.
The outpatient procedures were performed in approximately 45 minutes. Patients had a significant reduction in BMI at 12 months (mean [SD] BMI 39.9 +/- 5.1 kg/m(2) vs 30.6 +/- 4.7 kg/m(2); P or=40 kg/m(2), n = 33), group II (baseline BMI 35-40 kg/m(2), n = 19), and group III (baseline BMI <35 kg/m(2), n = 12) demonstrated a %EWL (SD) of 48.9 +/- 10.7, 56.5 +/- 13.9, and 85.1 +/- 24.0, respectively, at 12 months after the procedure (P = .037 when comparing group I vs II; P < .001 when comparing group II vs III and group I vs III). No patients experienced any serious adverse events.
This study represents a single center's clinical experience, with no sham control.
Endoluminal vertical gastroplasty by using a continuous suture pattern is associated with significant weight loss. Additional studies are needed to demonstrate the procedure's long-term safety and efficacy