8,142 research outputs found
Determining R-parity violating parameters from neutrino and LHC data
In supersymmetric models neutrino data can be explained by R-parity violating
operators which violate lepton number by one unit. The so called bilinear model
can account for the observed neutrino data and predicts at the same time
several decay properties of the lightest supersymmetric particle. In this paper
we discuss the expected precision to determine these parameters by combining
neutrino and LHC data and discuss the most important observables. We show that
one can expect a rather accurate determination of the underlying R-parity
parameters assuming mSUGRA relations between the R-parity conserving ones and
discuss briefly also the general MSSM as well as the expected accuracies in
case of a prospective e+ e- linear collider. An important observation is that
several parameters can only be determined up to relative signs or more
generally relative phases.Comment: 13 pages, 13 figure
Finding the Higgs Boson through Supersymmetry
The study of displaced vertices containing two b--jets may provide a double
discovery at the Large Hadron Collider (LHC): we show how it may not only
reveal evidence for supersymmetry, but also provide a way to uncover the Higgs
boson necessary in the formulation of the electroweak theory in a large region
of the parameter space. We quantify this explicitly using the simplest minimal
supergravity model with bilinear breaking of R-parity, which accounts for the
observed pattern of neutrino masses and mixings seen in neutrino oscillation
experiments.Comment: 7 pages, 7 figures. Final version to appear at PRD. Discussion and
results were enlarge
Probing Neutrino Oscillations in Supersymmetric Models at the Large Hadron Collider
The lightest supersymmetric particle may decay with branching ratios that
correlate with neutrino oscillation parameters. In this case the CERN Large
Hadron Collider (LHC) has the potential to probe the atmospheric neutrino
mixing angle with sensitivity competitive to its low-energy determination by
underground experiments. Under realistic detection assumptions, we identify the
necessary conditions for the experiments at CERN's LHC to probe the simplest
scenario for neutrino masses induced by minimal supergravity with bilinear R
parity violation.Comment: 11 pages, 6 figures. To appear in Physical Review
Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity.
Mycobacterium tuberculosis nicotinamidase-pyrazinamidase (PZAse) is a metalloenzyme that catalyzes conversion of nicotinamide-pyrazinamide to nicotinic acid-pyrazinoic acid. This study investigated whether a metallochaperone is required for optimal PZAse activity. M. tuberculosis and Escherichia coli PZAses (PZAse-MT and PZAse-EC, respectively) were inactivated by metal depletion (giving PZAse-MT-Apo and PZAse-EC-Apo). Reactivation with the E. coli metallochaperone ZnuA or Rv2059 (the M. tuberculosis analog) was measured. This was repeated following proteolytic and thermal treatment of ZnuA and Rv2059. The CDC1551 M. tuberculosis reference strain had the Rv2059 coding gene knocked out, and PZA susceptibility and the pyrazinoic acid (POA) efflux rate were measured. ZnuA (200 μM) achieved 65% PZAse-EC-Apo reactivation. Rv2059 (1 μM) and ZnuA (1 μM) achieved 69% and 34.3% PZAse-MT-Apo reactivation, respectively. Proteolytic treatment of ZnuA and Rv2059 and application of three (but not one) thermal shocks to ZnuA significantly reduced the capacity to reactivate PZAse-MT-Apo. An M. tuberculosis Rv2059 knockout strain was Wayne positive and susceptible to PZA and did not have a significantly different POA efflux rate than the reference strain, although a trend toward a lower efflux rate was observed after knockout. The metallochaperone Rv2059 restored the activity of metal-depleted PZAse in vitro Although Rv2059 is important in vitro, it seems to have a smaller effect on PZA susceptibility in vivo. It may be important to mechanisms of action and resistance to pyrazinamide in M. tuberculosis Further studies are needed for confirmation.IMPORTANCE Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis and remains one of the major causes of disease and death worldwide. Pyrazinamide is a key drug used in the treatment of tuberculosis, yet its mechanism of action is not fully understood, and testing strains of M. tuberculosis for pyrazinamide resistance is not easy with the tools that are presently available. The significance of the present research is that a metallochaperone-like protein may be crucial to pyrazinamide's mechanisms of action and of resistance. This may support the development of improved tools to detect pyrazinamide resistance, which would have significant implications for the clinical management of patients with tuberculosis: drug regimens that are appropriately tailored to the resistance profile of a patient's individual strain lead to better clinical outcomes, reduced onward transmission of infection, and reduction of the development of resistant strains that are more challenging and expensive to treat
The effect of Co and Zn addition on densification and electrical properties of ceria-based nanopowders
CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORIn this work, cobalt and zinc-doped Ce0.8Gd0.2O1.9 samples were prepared starting from a commercial nanopowder and compared to the undoped material. The powder samples were pressed and afterwards sintered by a two-step procedure, before characterization by X-Ray Diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Impedance Spectroscopy (IS) in air. Cobalt or zinc additions are effective as sintering aid, allowing peak sintering temperatures around 1000 degrees C to reach densifications above of 93% of theoretical density, showing no evidence for the presence of secondary phases. The total conductivity at 800 degrees C of pressed Zn-doped samples (6.7x10(-2) S/cm) and Co-doped samples (7.5x10(-2) S/cm) is similar for undoped samples (7.2x10(-2) S/cm) showing that Zn and Co has a positive effect on densification without compromising the electrical conductivity.In this work, cobalt and zinc-doped Ce0.8Gd0.2O1.9 samples were prepared starting from a commercial nanopowder and compared to the undoped material. The powder samples were pressed and afterwards sintered by a two-step procedure, before characterization by X-Ray Diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Impedance Spectroscopy (IS) in air. Cobalt or zinc additions are effective as sintering aid, allowing peak sintering temperatures around 1000 degrees C to reach densifications above of 93% of theoretical density, showing no evidence for the presence of secondary phases. The total conductivity at 800 degrees C of pressed Zn-doped samples (6.7x10(-2) S/cm) and Co-doped samples (7.5x10(-2) S/cm) is similar for undoped samples (7.2x10(-2) S/cm) showing that Zn and Co has a positive effect on densification without compromising the electrical conductivity.19510571063CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORSem informaçãoSem informaçãoFinancial supports from CAPES and CNPq are greatly appreciated. We would like to thank Rita C. G. Vinhas (State University of Campinas, Campinas Campus, Brazil), for helping with the XPS measurements
Study of RFe12−xMox (R =Y, Ho) compounds by neutron powder diffraction, ac susceptibility and magnetization
Neutron powder diffraction, magnetization and ac susceptibility measurements were
performed on compounds of the series RFe12−xMox (R D Y and Ho, x D 1, 2, 3). The influence of
the Mo content on both structural and magnetic properties is discussed. Comparison with published
data for different Mo concentrations is made. It is found that the effect of Mo substitution for Fe
on structural and magnetic properties can be described by two regimes separated by a critical Mo
content around x=2.Portuguese-French JNICT-CNRS collaboration
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