Association between disability measures and healthcare costs after initial treatment for acute stroke

<p><b>Background and Purpose:</b> The distribution of 3-month modified Rankin scale (mRS) scores has been used as an outcome measure in acute stroke trials. We hypothesized that hospitalization and institutional care home stays within the first 90 days after stroke should be closely related to 90-day mRS, that each higher mRS category will reflect incremental cost, and that resource use may be less clearly linked to the National Institutes of Health Stroke Scale (NIHSS) or Barthel index.</p> <p><b>Methods:</b> We examined resource use data from the GAIN International trial comparing 90-day mRS with total length of stay in hospital or other institutions during the first 90 days. We repeated analyses using NIHSS and Barthel index scores. Relationships were examined by analysis of variance (ANOVA) with Bonferroni contrasts of adjacent score categories. Estimated costs were based on published Scottish figures.</p> <p><b>Results:</b> We had full data from 1717 patients. Length of stay was strongly associated with final mRS (P<0.0001). Each mRS increment from 0 to 1–2 to 3–4 was significant (mean length of stay: 17, 25, 44, 58, 79 days; P<0.0005). Ninety-five percent confidence limits for estimated costs (£) rose incrementally: 2493 to 3412, 3369 to 4479, 5784 to 7008, 7300 to 8512, 10 095 to 11 141, 11 772 to 13 560, and 2623 to 3321 for mRS 0 to 5 and dead, respectively. Weaker relationships existed with Barthel and NIHSS.</p> <p><b>Conclusions:</b> Each mRS category reflects different average length of hospital and institutional stay. Associated costs are meaningfully different across the full range of mRS outcomes. Analysis of the full distribution of mRS scores is appropriate for interpretation of treatment effects after acute stroke and more informative than Barthel or NIHSS end points.</p&gt

Interacting Three Fluid System and Thermodynamics of the Universe Bounded by the Event Horizon

The work deals with the thermodynamics of the universe bounded by the event horizon. The matter in the universe has three constituents namely dark energy, dark matter and radiation in nature and interaction between then is assumed. The variation of entropy of the surface of the horizon is obtained from unified first law while matter entropy variation is calculated from the Gibbss' law. Finally, validity of the generalized second law of thermodynamics is examined and conclusions are written point wise.Comment: 7 page

Using Remote Sensing and Spatial Information Technologies to Detect and Map Two Aquatic Macrophytes

This paper describes the light reflectance characteristics ofwaterhyacinth [Eichhornia crassipes (Mort.) Solms] and hydrilla [Hydrilla verticillata (L.F.) Royle] and the application of airborned videography with global positioning system (GPS) and geographic information system (GIS) technologies for distinguishing and mapping the distribution of these two aquatic weeds in waterways of southern Texas. Field reflectance measurements made at several locations showed that waterhyacinth generally had higher near-infrared (NIR) reflectance than associated plant species and water. Hydrilla had lower NIR reflectance than associated plant species and higher NIR reflectance than water. Reflectance measurements made on hydrilla plants submerged below the water surface had similar spectral characteristics to water. Waterhyacinth and hydrilla could be distinguished in color-infrared (CIR) video imagery where they had bright orange-red and reddish-brown image responses, respectively. Computer analysis of the imagery showed that waterhyacinth and hydrilla infestaions could be quantified. An accuracy assessment performed on the classified image showed an overall accuracy of 87.7%. Integration of the GPS with the video imagery permitted latitude/longitude coordinates of waterhyacinth and hydrilla infestation to be recorded on each image. A portion of the Rio Grande River in extreme southern Texas was flown with the video system to detect waterhyacinth and hydrilla infestaions. The GPS coordinates on the CIR video scenes depicting waterhyacinth and hydrilla infestations were entered into a GIS to map the distribution of these two noxious weeds in the Rio Grande River

Dynamics of the self-interacting chameleon cosmology

In this article we study the properties of the flat FRW chameleon cosmology in which the cosmic expansion of the Universe is affected by the chameleon field and dark energy. In particular, we perform a detailed examination of the model in the light of numerical analysis. The results illustrate that the interacting chameleon filed plays an important role in late time universe acceleration and phantom crossing.Comment: 13 pages, 8 figures, to appear in Astrophysics and Space Sc

Cosmological Evolution Across Phantom Crossing and the Nature of the Horizon

In standard cosmology, with the evolution of the universe, the matter density and thermodynamic pressure gradually decreases. Also in course of evolution, the matter in the universe obeys (or violates) some restrictions or energy conditions. If the matter distribution obeys strong energy condition (SEC), the universe is in a decelerating phase while violation of SEC indicates an accelerated expansion of the universe. In the period of accelerated expansion the matter may be either of quintessence nature or of phantom nature depending on the fulfilment of the weak energy condition (WEC) or violation of it. As recent observational evidences demand that the universe is going through an accelerated expansion so mater should be either quintessence or phantom in nature. In the present work we study the evolution of the universe through the phantom barrier (i.e. the dividing line between the quintessence and phantom era) and examine how apparent and event horizon change across the barrier. Finally, we investigate the possibility of occurrence of any singularity in phantom era.Comment: 7 pages and 4 figure

The stringy nature of the 2d type-0A black hole

We investigate the thermodynamics of the RR charged two-dimensional type-0A black hole background at finite temperature, and compare with known 0A matrix model results. It has been claimed that there is a disagreement for the free energy between the spacetime and the dual matrix model. Here we find that this discrepancy is sensitive to how the cutoff is implemented on the spacetime side. In particular, the disagreement is resolved once we put the cutoff at a fixed distance away from the horizon, as opposed to a fixed position in space. Furthermore, the mass and the entropy of the black hole itself add up to an analytic contribution to the free energy, which is precisely reproduced by the 0A matrix model. We also use results from the 0A matrix model to predict the next to leading order contribution to the entropy of the black hole. Finally, we note that the black hole is characterized by a Hagedorn growth in its density of states below the Hagedorn temperature. This, together with other results, suggests there is a phase transition at this temperature.Comment: 1+21 pages; v2: Substantial changes in the body of the paper, main results the same. Clarified discussion on the thermodynamics, added section on a phase transition, references added. v3: Typos corrected. v4: Final version, to appear in JHE

Microfluidic and Nanofluidic Cavities for Quantum Fluids Experiments

The union of quantum fluids research with nanoscience is rich with opportunities for new physics. The relevant length scales in quantum fluids, 3He in particular, are comparable to those possible using microfluidic and nanofluidic devices. In this article, we will briefly review how the physics of quantum fluids depends strongly on confinement on the microscale and nanoscale. Then we present devices fabricated specifically for quantum fluids research, with cavity sizes ranging from 30 nm to 11 microns deep, and the characterization of these devices for low temperature quantum fluids experiments.Comment: 12 pages, 3 figures, Accepted to Journal of Low Temperature Physic

Condensing Momentum Modes in 2-d 0A String Theory with Flux

We use a combination of conformal perturbation theory techniques and matrix model results to study the effects of perturbing by momentum modes two dimensional type 0A strings with non-vanishing Ramond-Ramond (RR) flux. In the limit of large RR flux (equivalently, mu=0) we find an explicit analytic form of the genus zero partition function in terms of the RR flux $q$ and the momentum modes coupling constant alpha. The analyticity of the partition function enables us to go beyond the perturbative regime and, for alpha>> q, obtain the partition function in a background corresponding to the momentum modes condensation. For momenta such that 0<p<2 we find no obstruction to condensing the momentum modes in the phase diagram of the partition function.Comment: 22 page

Winding effects on brane/anti-brane pairs

We study a brane/anti-brane configuration which is separated along a compact direction by constructing a tachyon effective action which takes into account transverse scalars. Such an action is relevant in the study of HQCD model of Sakai and Sugimoto of chiral symmetry breaking, where the size of the compact circle sets the confinement scale. Our approach is motivated by string theory orbifold constructions and gives a route to model inhomogeneous tachyon decay. We illustrate the techniques involved with a relatively simple example of a harmonic oscillator on a circle. We will then repeat the analysis for the Sakai-Sugimoto model and show that by integrating out the winding modes will provide us with a renormalized action with a lower energy than that of truncating to zero winding sector.Comment: 21 pages, 3 figures. v3: discussion and references added, published versio

Geometric and thermodynamic properties in Gauss-Bonnet gravity

In this paper, the generalized second law (GSL) of thermodynamics and entropy is revisited in the context of cosmological models in Gauss-Bonnet gravity with the boundary of the universe is assumed to be enclosed by the dynamical apparent horizon. The model is best fitted with the observational data for distance modulus. The best fitted geometric and thermodynamic parameters such as equation of state parameter, deceleration parameter and entropy are derived. To link between thermodynamic and geometric parameters, the "entropy rate of change multiplied by the temperature" as a model independent thermodynamic state parameter is also derived. The results show that the model is in good agreement with the observational analysis.Comment: 13 pages, 13 figures, to be published in Astrophysics and Space Sc