Interprofessional Education Enhancement: Inclusion of Occupational Therapy

The increase in interprofessional education (IPE) opportunities provides an excellent opportunity for occupational therapy (OT) educators to partner with other health professions to deepen the understanding of how the OT profession adds value to future healthcare teams. The purpose of this study was to describe the development and impact of a curricular unit about the OT profession that was integrated into an established IPE program for medical, advanced practice nursing, pharmacy and social work students. A Needs Assessment was conducted by embedding an OT consultant within interprofessional student teams working in clinical environments over six weeks to observe baseline understanding of how student primary care teams work with OT professionals. From these observations, a curricular unit was designed that included lecture, interactive work stations, and case studies. Students completed pre and post surveys in order to assess their learning. Quantitative and qualitative analysis of pre and post surveys indicated a significant increase in knowledge, application of information, and confidence to refer to and utilize OT in clinical practice. Interprofessional students learned about OT scope of practice, possible interventions, and examples of appropriate referrals. The curricular unit provided an excellent example of how OT professionals can partner with health professions schools to provide content about OT when OT students are not accessible. Future improvements include assessment of longitudinal impact of the curriculum on health professions behavior, including impact on patient referrals to OT by primary care teams

Rewriting the History of the Native Mounted Police in Queensland

The Archaeology of the Native Mounted Police in Queensland project, jointly led by Nulungu research fellow Dr Lynley Wallis, is a long-overdue exploration into the nature of frontier invasion. Several of our team members have worked in Queensland for many decades and, in every Aboriginal community in which we’ve worked, stories are told about the ‘killing times’ or the ‘war’, as community members call the period when the Native Mounted Police (NMP, also referred to as the ‘Native Police’) were operating. Many community members have asked us over the years to record their stories about the massacres that took place, or have shown us places associated with the police camps or the massacre sites, and often told us that they would like to know more about what happened. These requests eventually led to the archaeologists on this project coming together, talking with key Aboriginal people and communities, and developing a research project to address their interests — the project described in this paper is the result.https://researchonline.nd.edu.au/nulungu_insights/1000/thumbnail.jp

Charged Higgs phenomenology in the flipped two Higgs doublet model

We study the phenomenology of the charged Higgs boson in the "flipped" two Higgs doublet model, in which one doublet gives mass to up-type quarks and charged leptons and the other gives mass to down-type quarks. We present the charged Higgs branching ratios and summarize the indirect constraints. We extrapolate existing LEP searches for H+H- and Tevatron searches for t tbar with t --> H+ b into the flipped model and extract constraints on MH+ and the parameter tan(beta). We finish by reviewing existing LHC charged Higgs searches and suggest that the LHC reach in this model could be extended for charged Higgs masses below the tb threshold by considering t tbar with t --> H+ b and H+ --> q qbar, as has been used in Tevatron searches.Comment: 23 pages, 7 figures. V2: added refs on H+W- associated productio

A revised edition of the readiness to change questionnaire (treatment version)

The UK Alcohol Treatment Trial provided an opportunity to examine the factor structure of the Readiness to Change Questionnaire-Treatment Version (RCQ[TV]) in a large sample (N = 742) of individuals in treatment for alcohol problems who were given the RCQ[TV] at baseline, 3-months and 12-months follow-up. Confirmatory factor analysis of the previously reported factor structure (5 items for each of Precontemplation, Contemplation and Action scales) resulted in a relatively poor fit to the data. Removal of one item from each of the scales resulted in a 12-item instrument for which goodness-of-fit indices were improved, without loss of internal consistency of the three scales, on all three measurement occasions. Inspection of relationships between stage allocation by the new instrument and negative alcohol outcome expectancies provided evidence of improved construct validity for the revised edition of the RCQ[TV]. There was also a strong relationship between stage allocation at 3-months follow-up and outcome of treatment at 12 months. The revised edition of the RCQ[TV] offers researchers and clinicians a shorter and improved measurement of stage of change in the alcohol treatment population

Different Observational Methods and the Detection of Seasonal and Atlantic Influence Upon Phytoplankton Communities in the Western Barents Sea

Phytoplankton community composition, and its dependency on environmental variation, are key to understanding marine primary production, processes of trophic transfer and the role of marine phytoplankton in global biogeochemical cycles. Understanding changes in phytoplankton community composition on Arctic shelves is important, because these productive environments are experiencing rapid change. Many different methods have been employed by researchers to quantify phytoplankton community composition. Previous studies have demonstrated that the way in which community composition is quantified can influence the interpretation of environmental dependencies. Researchers must consider both the suitability of the data they collect for monitoring marine ecosystems, as well as the research effort required to collect representative datasets. We therefore seek to understand how the representation of phytoplankton community structure in the western Barents Sea, a rapidly changing Arctic shelf sea, influences the interpretation of environmental dependencies. We compare datasets of cell counts, phytoplankton pigments and bio-optics (absorption spectra), relating them to a suite of environmental conditions with multivariate exploratory analyses. We show that, while cell counts reveal the greatest insight into environmental dependencies, pigment and absorption spectral datasets still provide useful information about seasonal succession and the influence of Atlantic water masses– two key subjects of great research interest in this region. As pigments and optical properties influence remotely-sensed ocean-colour, these findings hold implications for remote detection of phytoplankton community composition

The difficult, divisive and disruptive heritage of the Queensland Native Mounted Police

The colonial history of nineteenth-century Queensland was arguably dominated by the actions of the Native Mounted Police, Australia’s most punitive native policing force. The centrality of the Native Mounted Police to the sustained economic success of Queensland for over half a century, and their widespread, devastating effects on Aboriginal societies across the colony, have left a complex legacy. For non-Indigenous Queenslanders, a process of obscuring the Native Mounted Police began perhaps as soon as a detachment was removed from an area, reflected today in the minimisation of the Native Mounted Police in official histories and their omission from non-Indigenous heritage lists. In contrast, the Aboriginal Cultural Heritage Database preserves several elements of frontier conflict and Native Mounted Police presence, giving rise to parallel state-level narratives, neither of which map directly onto local and regional memory. This highlights potential issues for formal processes of truth-telling relating to frontier conflict that have recently been initiated by the Queensland and Federal Governments. Of particular concern is the form that such a process might adopt. Drawing on a 4-year project to document the workings of the Queensland Native Mounted Police through archival, archaeological and oral historical sources, we suggest that this conflicted and conflictual heritage can best be bridged through empathetic truth-telling, using Rothberg’s notion of the implicated subject to consider contemporary contexts of responsibility and connect present-day Queenslanders with this difficult, divisive and disruptive past

Exploring perceptions of meaningfulness in visual representations of bivariate relationships

Researchers often need to consider the practical significance of a relationship. For example, interpreting the magnitude of an effect size or establishing bounds in equivalence testing requires knowledge of the meaningfulness of a relationship. However, there has been little research exploring the degree of relationship among variables (e.g., correlation, mean difference) necessary for an association to be interpreted as meaningful or practically significant. In this study, we presented statistically trained and untrained participants with a collection of figures that displayed varying degrees of mean difference between groups or correlations among variables and participants indicated whether or not each relationship was meaningful. The results suggest that statistically trained and untrained participants differ in their qualification of a meaningful relationship, and that there is significant variability in how large a relationship must be before it is labeled meaningful. The results also shed some light on what degree of relationship is considered meaningful by individuals in a context-free setting

Individual Differences in Amygdala and Ventromedial Prefrontal Cortex Activity are Associated with Evaluation Speed and Psychological Well-being

Using functional magnetic resonance imaging, we examined whether individual differences in amygdala activation in response to negative relative to neutral information are related to differences in the speed with which such information is evaluated, the extent to which such differences are associated with medial prefrontal cortex function, and their relationship with measures of trait anxiety and psychological well-being (PWB). Results indicated that faster judgments of negative relative to neutral information were associated with increased left and right amygdala activation. In the prefrontal cortex, faster judgment time was associated with relative decreased activation in a cluster in the ventral anterior cingulate cortex (ACC, BA 24). Furthermore, people who were slower to evaluate negative versus neutral information reported higher PWB. Importantly, higher PWB was strongly associated with increased activation in the ventral ACC for negative relative to neutral information. Individual differences in trait anxiety did not predict variation in judgment time or in amygdala or ventral ACC activity. These findings suggest that people high in PWB effectively recruit the ventral ACC when confronted with potentially aversive stimuli, manifest reduced activity in subcortical regions such as the amygdala, and appraise such information as less salient as reflected in slower evaluative speed

Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines

Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic drivers of the disease. While many of these cell lines have been previously characterized with SNP, methylation, and/or mRNA expression microarrays, there has not been an effort to comprehensively sequence these cell lines. Here, we present raw whole transcriptome data generated by RNA sequencing of 39 commonly-used neuroblastoma cell lines. These data can be used to perform differential expression analysis based on a genetic aberration or phenotype in neuroblastoma (e.g., MYCN amplification status, ALK mutation status, chromosome arm 1p, 11q and/or 17q status, sensitivity to pharmacologic perturbation). Additionally, we designed this experiment to enable structural variant and/or long-noncoding RNA analysis across these cell lines. Finally, as more DNase/ATAC and histone/transcription factor ChIP sequencing is performed in these cell lines, our RNA-Seq data will be an important complement to inform transcriptional targets as well as regulatory (enhancer or repressor) elements in neuroblastoma

Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults

Among younger adults, the ability to willfully regulate negative affect, enabling effective responses to stressful experiences, engages regions of prefrontal cortex (PFC) and the amygdala. Because regions of PFC and the amygdala are known to influence the hypothalamic-pituitary-adrenal axis, here we test whether PFC and amygdala responses during emotion regulation predict the diurnal pattern of salivary cortisol secretion. We also test whether PFC and amygdala regions are engaged during emotion regulation in older (62- to 64-year-old) rather than younger individuals. We measured brain activity using functional magnetic resonance imaging as participants regulated (increased or decreased) their affective responses or attended to negative picture stimuli. We also collected saliva samples for 1 week at home for cortisol assay. Consistent with previous work in younger samples, increasing negative affect resulted in ventral lateral, dorsolateral, and dorsomedial regions of PFC and amygdala activation. In contrast to previous work, decreasing negative affect did not produce the predicted robust pattern of higher PFC and lower amygdala activation. Individuals demonstrating the predicted effect (decrease s attend in the amygdala), however, exhibited higher signal in ventromedial prefrontal cortex (VMPFC) for the same contrast. Furthermore, participants displaying higher VMPFC and lower amygdala signal when decreasing compared with the attention control condition evidenced steeper, more normative declines in cortisol over the course of the day. Individual differences yielded the predicted link between brain function while reducing negative affect in the laboratory and diurnal regulation of endocrine activity in the home environment