Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors-2

<p><b>Copyright information:</b></p><p>Taken from "Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors"</p><p></p><p>Bioinformation 2006;1(5):170-175.</p><p>Published online 19 Jul 2006</p><p>PMCID:PMC1891684.</p><p></p

Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors-1

<p><b>Copyright information:</b></p><p>Taken from "Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors"</p><p></p><p>Bioinformation 2006;1(5):170-175.</p><p>Published online 19 Jul 2006</p><p>PMCID:PMC1891684.</p><p></p

Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors-0

<p><b>Copyright information:</b></p><p>Taken from "Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors"</p><p></p><p>Bioinformation 2006;1(5):170-175.</p><p>Published online 19 Jul 2006</p><p>PMCID:PMC1891684.</p><p></p

Straightforward, One-Step Synthesis of Alkanethiol-capped Silver Nanoparticles from an Aggregative Model of Growth

Classical nucleation theory and Derjaguin, Landau, Verwey, Overbeek (DLVO) theory for colloidal stability were applied to gain insight into the synthesis of dodecanethiol (DDT) functionalized silver nanoparticles (NPs) by reduction of silver nitrate with sodium borohydride in ethanol. This analysis indicated the importance of quickly establishing a dense DDT ligand brush on inherently unstable primary particles to achieve colloidal stability. The DLVO calculations also indicated that the electrostatic potential was a minor contributor to repulsive interactions, signifying that it would be possible to control NP size and uniformity in solutions with high ionic strength, as long as sufficient DDT was available to form a densely packed ligand layer on the NPs. These insights were applied to design a new straightforward, one-step, one-phase synthesis for the production of alkanethiol-functionalized silver NPs. To test the insights from DLVO theory, 16 samples were synthesized in the parameter space <i>R</i> = 3–12, <i>S</i> = 1–12 where <i>R</i> = [NaBH₄]/[AgNO₃], <i>S</i> = [DDT]/[AgNO₃], and [AgNO₃] = 10 mM. In general, samples with <i>R</i> = 3 or <i>S</i> = 1 were polydisperse; however, samples in the <i>R</i> = 6–12 and <i>S</i> = 3–12 range had uniform particle sizes with average diameters between 3.5 and 4.7 nm. Additionally, samples with <i>R</i> = 72–108 and <i>S</i> = 12 were synthesized to test particle stability at high ionic strength; again, uniform NPs with average diameters from 3.5 to 3.8 nm were produced. Ultimately, the insights gained from DLVO theory successfully guided the development of a one-step, one-phase technique for the synthesis of uniform, spherical alkanethiol-functionalized silver NPs

Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors-3

<p><b>Copyright information:</b></p><p>Taken from "Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors"</p><p></p><p>Bioinformation 2006;1(5):170-175.</p><p>Published online 19 Jul 2006</p><p>PMCID:PMC1891684.</p><p></p

Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors-4

<p><b>Copyright information:</b></p><p>Taken from "Fusion of FNA-cytology and Gene-expression Data Using Dempster-Shafer Theory of Evidence to Predict Breast Cancer Tumors"</p><p></p><p>Bioinformation 2006;1(5):170-175.</p><p>Published online 19 Jul 2006</p><p>PMCID:PMC1891684.</p><p></p

Additional file 1: Figure S1. of The effect of long-term confinement and the efficacy of exercise countermeasures on muscle strength during a simulated mission to Mars: data from the Mars500 study

Treadmill: (A–C) Treadmill protocol for day 1 (A), day 2 (B), and day 3 (C). Areas where the line is 0 km/h denote pre-defined breaks in the profile. Cycling: (D–F) Profiles for days 1 (D), 2 (E), and 3 (F) on the cycle ergometer. Different profiles provided variability to maximize potential physiological adaptation and prevent boredom, thereby aiding compliance. (PNG 138 kb

Small carnivore competition

4 data files required to replicate our analyses, including: "GeneticSamples.csv", "SiteLocations.csv", "SiteVisits.csv", and "TrackPlates.csv". Data were collected from sites in northern California and southern Oregon, USA

PEG-modification of rabbit IgG results in higher accumulation in brain tissue.

<p>(A) PEG-modification of IgG leads to elevated concentrations in the blood at early time points, but is diminished by 48 h. Holm-Sidak post-hoc test after a two-factor ANOVA (antibody and time) revealed significant differences at 6 h (p<0.001) and 18 h (p = 0.027). (B) In contrast, the penetration of IgG into the brain is elevated at the intermediate time points, but by 48 h the effects of PEG-modification begin to diminish in the brain. Holm-Sidak post-hoc test after a two-factor ANOVA (antibody and time) revealed significant differences at 18 h (p<0.001 and 48 h (p<0.001) (n = 4, mean ± standard deviation plotted).</p