Logistics salience impact on logistics capabilities and performance

Purpose – The purpose of this manuscript is to assess the impact of logistics salience on logistics capabilities and performance. Specifically, the impact of logistics salience on logistics innovativeness and logistics service differentiation is measured along with logistics innovativeness and logistics service differentiation effect on logistics performance. Design/methodology/approach – Conclusions were drawn from survey data gathered from logistics and supply chain managers at US firms. Structural equation modelling was utilized to measure the statistical significance of the hypothesized model paths with all findings meeting the basic requirements of interpretation. Findings – The results suggest that logistics salience positively impacts both logistics innovativeness and logistics service differentiation. Logistics innovativeness and logistics service differentiation both positively influence logistics performance. These findings give credence to the resource based view of the firm which states that resources lead to capabilities which leads to performance. Research limitations/implications – Conclusions based on the study’s results highlight the importance of logistics within firms and indicate that the function must be made salient throughout the firm to further capitalize on the benefits of logistics. These benefits include enhanced logistics capabilities and their eventual impact on logistics performance. Originality/value – Using the resource based view of the firm as the theoretical framework, the manuscript supports the notion that logistics salience is an important resource for firms looking to provide differentiated services and innovative logistics operations to their customers

Automatic replenishment: the relationship between resource commitment and program performance

Some firms have adopted a new approach to order fulfillment, i.e., automatic inventory replenishment. With automatic replenishment programs (ARPs), sellers replenish or restock inventory based upon actual product usage and stock level information provided by buyers. This paper reports on a recent survey of logistics professionals regarding .ARP involvement. In addition to providing a profile of current usage, the research also examines the relationship between investment in automatic replenishment related resources and .ARP performance. Firms making a greater commitment to ARP (in terms of resource allocation) reported enhanced day-to-day operational performance and greater success in the overall performance of the trading relationship

Profit contribution information’s impact on internal integration

An exploratory quantitative study on the relationship between profit contribution information and firm-wide internal integration is presented. Specifically, the authors examine how profit contribution information availability impacts firm-wide internal integration and, subsequently, logistics performance. This study provides greater insight into the area; only a few studies have empirically examined the impact of profit contribution information within a firm. The primary implication is that firms should utilize specific types of information, i.e. profit contribution information, for making more informed operational and strategic decisions. The paper also underscores the managerial value of using profit contribution information in decision making and planning

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

The impact of operating environment on the formation of cooperative logistics relationships

Increased outsourcing of logistical services by manufacturers has prompted reconsideration of traditional relationships between manufacturers and third party logistics firms. Firms are moving away from single transaction business arrangements and forming cooperative relationships with third party providers characterized by cooperative transactions occurring over time. Analysis of data collected from a random sample of manufacturing executives identifies operating conditions in the manufacturers' operating and strategic environment that are best suited for cooperative relationship formation in an international logistics setting.