6,248 research outputs found
Non-equilibrium inelastic electronic transport: Polarization effects and vertex corrections to the self-consistent Born approximation
We study the effect of electron-vibron interactions on the inelastic
transport properties of single-molecule nanojunctions. We use the
non-equilibrium Green's functions technique and a model Hamiltonian to
calculate the effects of second-order diagrams (double-exchange DX and
dressed-phonon DPH diagrams) on the electron-vibration interaction and consider
their effects across the full range of parameter space. The DX diagram,
corresponding to a vertex correction, introduces an effective dynamical
renormalization of the electron-vibron coupling in both the purely inelastic
and the inelastic-resonant features of the IETS. The purely inelastic features
correspond to an applied bias around the energy of a vibron, while the
inelastic-resonant features correspond to peaks (resonance) in the conductance.
The DPH diagram affects only the inelastic resonant features. We also discuss
the circumstances in which the second-order diagrams may be approximated in the
study of more complex model systems.Comment: To be published in PR
Navigation control of an automated mobile robot robot using neural network technique
Over recent years, automated mobile robots play a crucial role in various navigation operations. For any mobile device, the capacity to explore in its surroundings is essential. Evading hazardous circumstances, for example, crashes and risky conditions (temperature, radiation, presentation to climate, and so on.) comes in the first place, yet in the event that the robot has a reason that identifies with particular places in its surroundings, it must discover those spots. There is an increment in examination here due to the requisition of mobile robots in a solving issues like investigating natural landscape and assets, transportation tasks, surveillance, or cleaning. We require great moving competencies and a well exactness for moving in a specified track in these requisitions. Notwithstanding, control of these navigation bots get to be exceptionally troublesome because of the exceedingly unsystematic and dynamic aspects of the surrounding world. The intelligent reply to this issue is the provision of sensors to study the earth. As neural networks (NNs) are described by adaptability and a fitness for managing non-linear problems, they are conceived to be useful when utilized on navigation robots. In this exploration our computerized reasoning framework is focused around neural network model for control of an Automated motion robot in eccentric and unsystematic nature. Hence the back propagation algorithm has been utilized for controlling the direction of the mobile robot when it experiences by an obstacle in the left, right and front directions. The recreation of the robot under different deterrent conditions is carried out utilizing Arduino which utilizes C programs for usage
Extra-matrix Mg\u3csup\u3e2+\u3c/sup\u3e Limits Ca\u3csup\u3e2+\u3c/sup\u3e Uptake and Modulates Ca\u3csup\u3e2+\u3c/sup\u3e Uptake-independent Respiration and Redox State in Cardiac Isolated Mitochondria
Cardiac mitochondrial matrix (m) free Ca2+ ([Ca2+]m) increases primarily by Ca2+ uptake through the Ca2+ uniporter (CU). Ca2+ uptake via the CU is attenuated by extra-matrix (e) Mg2+ ([Mg2+]e). How [Ca2+]m is dynamically modulated by interacting physiological levels of [Ca2+]e and [Mg2+]e and how this interaction alters bioenergetics are not well understood. We postulated that as [Mg2+]e modulates Ca2+ uptake via the CU, it also alters bioenergetics in a matrix Ca2+–induced and matrix Ca2+–independent manner. To test this, we measured changes in [Ca2+]e, [Ca2+]m, [Mg2+]e and [Mg2+]m spectrofluorometrically in guinea pig cardiac mitochondria in response to added CaCl2 (0–0.6 mM; 1 mM EGTA buffer) with/without added MgCl2 (0–2 mM). In parallel, we assessed effects of added CaCl2 and MgCl2 on NADH, membrane potential (ΔΨm), and respiration. We found that \u3e0.125 mM MgCl2 significantly attenuated CU-mediated Ca2+ uptake and [Ca2+]m. Incremental [Mg2+]e did not reduce initial Ca2+uptake but attenuated the subsequent slower Ca2+ uptake, so that [Ca2+]m remained unaltered over time. Adding CaCl2 without MgCl2 to attain a [Ca2+]m from 46 to 221 nM enhanced state 3 NADH oxidation and increased respiration by 15 %; up to 868 nM [Ca2+]m did not additionally enhance NADH oxidation or respiration. Adding MgCl2 did not increase [Mg2+]m but it altered bioenergetics by its direct effect to decrease Ca2+ uptake. However, at a given [Ca2+]m, state 3 respiration was incrementally attenuated, and state 4 respiration enhanced, by higher [Mg2+]e. Thus, [Mg2+]e without a change in [Mg2+]m can modulate bioenergetics independently of CU-mediated Ca2+ transport
The ART of IAM: The Winning Strategy for the 2006 Competition
In many dynamic open systems, agents have to interact with one another to achieve their goals. Here, agents may be self-interested, and when trusted to perform an action for others, may betray that trust by not performing the actions as required. In addition, due to the size of such systems, agents will often interact with other agents with which they have little or no past experience. This situation has led to the development of a number of trust and reputation models, which aim to facilitate an agent's decision making in the face of uncertainty regarding the behaviour of its peers. However, these multifarious models employ a variety of different representations of trust between agents, and measure performance in many different ways. This has made it hard to adequately evaluate the relative properties of different models, raising the need for a common platform on which to compare competing mechanisms. To this end, the ART Testbed Competition has been proposed, in which agents using different trust models compete against each other to provide services in an open marketplace. In this paper, we present the winning strategy for this competition in 2006, provide an analysis of the factors that led to this success, and discuss lessons learnt from the competition about issues of trust in multiagent systems in general. Our strategy, IAM, is Intelligent (using statistical models for opponent modelling), Abstemious (spending its money parsimoniously based on its trust model) and Moral (providing fair and honest feedback to those that request it)
Inhibition of prefrontal protein synthesis following recall does not disrupt memory for trace fear conditioning
BACKGROUND: The extent of similarity between consolidation and reconsolidation is not yet fully understood. One of the differences noted is that not every brain region involved in consolidation exhibits reconsolidation. In trace fear conditioning, the hippocampus and the medial prefrontal cortex (mPFC) are required for consolidation of long-term memory. We have previously demonstrated that trace fear memory is susceptible to infusion of the protein synthesis inhibitor anisomycin into the hippocampus following recall. In the present study, we examine whether protein synthesis inhibition in the mPFC following recall similarly results in the observation of reconsolidation of trace fear memory. RESULTS: Targeted intra-mPFC infusions of anisomycin or vehicle were performed immediately following recall of trace fear memory at 24 hours, or at 30 days, following training in a one-day or a two-day protocol. The present study demonstrates three key findings: 1) trace fear memory does not undergo protein synthesis dependent reconsolidation in the PFC, regardless of the intensity of the training, and 2) regardless of whether the memory is recent or remote, and 3) intra-mPFC inhibition of protein synthesis immediately following training impaired remote (30 days) memory. CONCLUSION: These results suggest that not all structures that participate in memory storage are involved in reconsolidation. Alternatively, certain types of memory-related information may reconsolidate, while other components of memory may not
Interconversion of tight and loose couple 50 S ribosomes and translocation in protein synthesis
On incubation of 50 S ribosomes, isolated from either tight couple (TC) or loose couple (LC) 70 S ribosomes, with elongation factor G (EG-G) and guanosine 5'-triphosphate, a mixture of TC and LC 50 S ribosomes is formed. There is almost complete conversion of LC 50 S ribosomes to TC 50 S ribosomes on treatment with EF-G, GTP, and fusidic acid. Similarly, TC 50 S ribosomes are converted to LC 50 S ribosomes, although partially, by treatment with EF-G and a GTP analogue like guanyl-5'-yl methylenediphosphate (GMP-P(CH2)P) or guanyl-5'-yl imidodiphosphate (GMP-P(NH)P) and including a polymer of 5'-uridylic acid (poly(U] in the incubation mixture. Furthermore, LC 23 S RNA isolated from LC 50 S ribosomes is converted to TC 23 S RNA on heat treatment, but similar treatment does not affect TC 23 S RNA. The interconversion was followed by several physical and biological characteristics of TC and LC 50 S ribosomes, like association capacities with 30 S ribosomes before and after kethoxal treatment, susceptibility to RNase I and polyphenylalanine-synthesizing capacity in association with 30 S ribosomes, as well as thermal denaturation profiles, circular dichroic spectra, and association capacity of isolated 23 S RNAs. These data strongly support the proposition that TC and LC 50 S ribosomes are the products of translocation during protein synthesis. The conformational change of 23 S RNA induced by EF-G and GTP is most probably responsible for the interconversion, and L7/L12 proteins play an important role in the process. A two-site model based on kethoxal data has also been proposed to explain the tightness and looseness of 70 S couples
Trust-Based Mechanisms for Robust and Efficient Task Allocation in the Presence of Execution Uncertainty
Vickrey-Clarke-Groves (VCG) mechanisms are often used to allocate tasks to selfish and rational agents. VCG mechanisms are incentive-compatible, direct mechanisms that are efficient (i.e. maximise social utility) and individually rational (i.e. agents prefer to join rather than opt out). However, an important assumption of these mechanisms is that the agents will always successfully complete their allocated tasks. Clearly, this assumption is unrealistic in many real-world applications where agents can, and often do, fail in their endeavours. Moreover, whether an agent is deemed to have failed may be perceived differently by different agents. Such subjective perceptions about an agent’s probability of succeeding at a given task are often captured and reasoned about using the notion of trust. Given this background, in this paper, we investigate the design of novel mechanisms that take into account the trust between agents when allocating tasks. Specifically, we develop a new class of mechanisms, called trust-based mechanisms, that can take into account multiple subjective measures of the probability of an agent succeeding at a given task and produce allocations that maximise social utility, whilst ensuring that no agent obtains a negative utility. We then show that such mechanisms pose a challenging new combinatorial optimisation problem (that is NP-complete), devise a novel representation for solving the problem, and develop an effective integer programming solution (that can solve instances with about 2×105 possible allocations in 40 seconds).
Dinuclear UO2(VI), Th(IV), ZrO(IV) and VO(IV) complexes based on some Schiff-base ligands: Synthesis and structural elucidation
A series of homo binuclear complexs of the type [M2(L/L’)(NO3)n(H2O)2], [where M=UO22+, Th4+, ZrO2+] and [(VO)2(L/L’)(SO4)(H2O)], L= 4, 17-di(o-hydroxyphenyl)-5,6,9,12,15,16-hexaaza-7,8,13,14-tetraphenyl heptadec-4, 6, 8, 12, 14, 16-hexene or L’= 10:11-benzo-4, 17-di(o-hydroxyphenyl)-5,6,9,12,15,16-hexaaza-7,8,13,14-tetraphenyl heptadec-4, 6, 8, 12, 14, 16-hexene, n=2 for UO22+, ZrO2+ n=6 for Th4+, have been synthesized in template method from ethylenediamine/orthophenylene diamine, benzil monohydrazone and salicyldehyde and characterized on the basis of elemental analysis, thermal analysis, molar conductivity, magnetic moment, electronic, infrared, 1H-NMR studies. The results indicate that the VO(IV) ion is penta co-ordinated yielding paramagnetic complexes; UO2(VI), ZrO(IV) ions are hexa co-ordinated where as Th(IV) ion is octa co-ordinated yielding diamagnetic complexes of above composition
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