IMPACT OF STERIOD AND ANTIBIOTIC ON THE POTENTIAL TOCOLYTICS

To prevent premature labor always attempts are taken by the medication with Tocolytic. Along with Tocolytic, steroid and antibiotic are used for the proper therapy to prevent premature labor. The present study will evaluate the impact of the selected steroid (bethamethasone) and antibiotic (ampicillin) on the uterine relaxant effect of the selected Tocolytic (indomethacine).This study will be helpful for the proper medication during the preventation of premature labor along with a better medication and better result. Evaluation of impact of the selected drugs (betamethasone,ampicillin) on the efficacy of the selected Tocolytic (indomethacine)  by in vitro method using oxytocin as a uterine contractile agent on rat uterus. The rat's uterine preparation is used for the present study and the sensitivity of uterus is depends upon the oestrus cycles.Oxytocin cause the contraction of the uterine muscle by acting on the muscuarinic receptor. Tocolytic block muscarinic receptor of uterine muscle. Therefore, in this study the Tocolytic reduce oxytocin induced contraction in rat uterine. The concentration response cruve of oxytocin was shifted to the right in the presence of Tocolytic.  Afterwards the effect of the selected steroid and antibiotic in presence of the Tocolytic are evaluated on the kymograph of oxytocin.it was observed that steroid and antibiotic decrease the potency of Tocolytic. KEYWORDS – Premature Labour,Tocolytic,Steroid,Antbiotic,Oxytocin,Betamethasone, Ampicillin,Indomethaci

PHYTO-PHARMACOLOGY of Berberis aristata DC: A REVIEW

ABSTRACT Plants have been the basis of many traditional medicines throughout the world for thousands of years and continue to provide new remedies to mankind. Plants are one of the richest sources of compounds. Berberis aristata is one of the plants used in Ayurveda for several remedies. Berberis aristata commonly known as  “Daru haldhi and Chitra†is spinous herb native to northern Himalaya region. The plant  is  widely distributed  from Himalayas to Srilanka, Bhutan,  and  hilly areas of  Nepal.  Berberis aristata is used  in ayurvedic  medicines  from  very  long time.  It is used as a tonic, alternative, demulscent, diaphoretic, and diuretic, in the treatment of diarrhoea, jaundice and skin diseases, syphilis, chronic rheumatism and urinary disorders. Scientific evidence suggests its versatile biological functions that support its traditional use in the orient.  Phytochemical  studies  shows  that  plant Berberis  aristata contains  mainly  yellow  colored alkaloids Berberine,  oxyberberine,  berbamine,  aromoline,  a  protoberberine  alkaloid  karachine,  palmatine, oxycanthine  and  taxilamine  and  tannins,  sugar,  starch.  The  plant  has  effective  pharmacological  action  and  shows promising future for further researches.  This review aims to highlight the ethnobotany, pharmacognostic and pharmacological uses of Berberis aristat

Therapeutic Potentials of Bambusa bambos Druce

ABSTRACT: From ancient times mankind is dependent on plant sources for the ailments of various disorders. Bambusa bambos is one of these medicinal plants, which is a large genus (about 37 species) of clumping bamboos. These species are usually giant ones, with numerous branches at a node and one or two much larger than the rest. They are found in tropical and subtropical areas of Asia, especially in the monsoon and wet Tropics. In growing Bamboo Above ground bio mass production and nutrient distribution require two days (0.12 m height) to maturity (28.5 m height), studied over five months. Literature review reveals that studies on food safety aspect of bamboo shoot are unsystematic and scanty hence need special attention. Present study highlights the therapeutic uses of Bambusa bambos along with the responsible chemical constituents

HERBS AGAINST CANCER: AN UPDAT

Medicinal herbs have been on the forefront whenever we talk about anticancer remedies, Herbal medicines have a vital role in the prevention and treatment of cancer. With advanced knowledge of molecular science and refinement in isolation and structure elucidation techniques, various anticancer herbs has been identified, which execute their therapeutic effect by inhibiting cancer-activating enzymes and hormones, stimulating DNA repair mechanism, promoting production of protective enzymes, inducing antioxidant action and enhancing immunity of the body. Here we Covered the plants used previously and recently identified for treatment of cancer and to reduce the pains during the treatment of cancer

The Landau Kleffner Syndrome

The Landau Kleffner   syndrome (LKS) or the syndrome of acquired epileptic aphasia was first described in 1957. LKS also called infantile acquired aphasia, acquired epileptic aphasia or aphasia with convulsive disorder. It is a rare childhood neurological syndrome. LKS is an epilepsy syndrome involving progressive neuropsychological impairment related to the appearance of paroxysmal electroencephalograph (EEG) activity. The disorder is characterized by gradual or rapid loss of language in a previously normal child. Affected children who have developed age-appropriate speech then experience language regression with verbal auditory agnosia, abnormal epileptiform activity, behavioural disturbances, and sometimes overt seizures. Behavioral disorders such as hyperactivity, aggressiveness and depression can also accompany this disorder

PHYTOCONSTITUENTS AND THERAPEUTIC POTENTIALS OF DATURA STRAMONIUM LINN

Datura stramonium Linn is one of the widely well known folklore medicinal herb. It is a wild growing flowering plant and was investigated as a local source for tropane alkaloids which contain a methylated nitrogen atom (N-CH3) and include the anti-cholinergic drugs atropine, and scopolamine. Some sources report a probable Central American origin, due to Datura's habitation of most temperate and subtropical parts of the world. This plant has contributed various pharmacological actions in the scientific field of Indian systems of medicines. The present paper will give exclusive information on the chemical constituents and mainly psychopharmacological activities of this plant

Drug abuse and its ramifications on skeletal system

The purpose of this study is to highlight the drug abuse hazards and preventive aspects. From a public health perspective, substance abuse has long been a source of major concern, both for the individual’s health and for wider society as a whole. The UK has the highest rates of recorded illegal drug misuse in the western world. In particular, it has comparatively high rates of heroin and crack cocaine use. Substances that are considered harmful are strictly regulated according to a classification system that takes into account the harms and risks of taking each drug. The adverse effects of drug abuse can be thought of in three parts that together determine the overall harm in taking it. Some addictive substances are more damaging to the skeletal system along with the others. In this review article, an effort has been taken to elaborate the effects of addictive drugs on human highlighting these most problematic substances for bones and also the promising potential prevention aspects of drug abuse

ANTIDEPRESSANT POTENTIAL OF ISOLATED BIOACTIVE COMPOUND FROM BUTEA MONOSPERMA (LAM.) KUNTZE

Traditional or alternative medicine refers other than orthodox medicine. From time immemorial, plants have been utilized as corrective agents for a variety of diseases. Butea monosperma (Lam.) Kuntze is a generally utilized plant in Ayurveda. Butea monosperma (Palas) has a place with the family Fabaceae, developed freely in many parts of India. Different phytochemical constituents present are carbohydrates, alkaloids, tannins, flavonoids, steroids and terpenoids. Butea monosperma is traditionally utilized as a free radical scavenger, antistress, CNS stimulant, antigout, diuretic, antileprotic, anti-inflammatory, antiulcer, astringent and antihepatotoxic. Its flower is utilized to treat instances of expanded spleen, menstrual aggravations, consuming sensations and eye diseases. Effect of Isolated bioactive compound from Methanol Extract of Butea monosperma (Lam.) Kuntze (BMME) was studied for the duration of immobility by Forced Swim Test (FST) At the dose of 20 mg/kg isolated compound showedsignificant effect (p<0.05) forduration of immobilitywhen compared with control group of animals. The monoamines are determined in mice brain to find out the altered levels of monoamines. It had been suggested that an increase in both swimming and climbing behaviors in the FST occurs when the animal is treated by a drug which increases NA and DA levels in the nerve terminals. An increase in NA and DA could be by inhibition of MAO activity in the brain