47 research outputs found
Extremely Large Area (88 mm X 88 mm) Superconducting Integrated Circuit (ELASIC)
Superconducting integrated circuit (SIC) is a promising "beyond-CMOS" device
technology enables speed-of-light, nearly lossless communications to advance
cryogenic (4 K or lower) computing. However, the lack of large-area
superconducting IC has hindered the development of scalable practical systems.
Herein, we describe a novel approach to interconnect 16 high-resolution deep UV
(DUV EX4, 248 nm lithography) full reticle circuits to fabricate an extremely
large (88mm X 88 mm) area superconducting integrated circuit (ELASIC). The
fabrication process starts by interconnecting four high-resolution DUV EX4 (22
mm X 22 mm) full reticles using a single large-field (44 mm X 44 mm) I-line
(365 nm lithography) reticle, followed by I-line reticle stitching at the
boundaries of 44 mm X 44 mm fields to fabricate the complete ELASIC field (88
mm X 88 mm). The ELASIC demonstrated a 2X-12X reduction in circuit features and
maintained high-stitched line superconducting critical currents. We examined
quantum flux parametron (QFP) circuits to demonstrate the viability of common
active components used for data buffering and transmission. Considering that no
stitching requirement for high-resolution EX4 DUV reticles is employed, the
present fabrication process has the potential to advance the scaling of
superconducting quantum devices
Learning-based Calibration of Flux Crosstalk in Transmon Qubit Arrays
Superconducting quantum processors comprising flux-tunable data and coupler
qubits are a promising platform for quantum computation. However, magnetic flux
crosstalk between the flux-control lines and the constituent qubits impedes
precision control of qubit frequencies, presenting a challenge to scaling this
platform. In order to implement high-fidelity digital and analog quantum
operations, one must characterize the flux crosstalk and compensate for it. In
this work, we introduce a learning-based calibration protocol and demonstrate
its experimental performance by calibrating an array of 16 flux-tunable
transmon qubits. To demonstrate the extensibility of our protocol, we simulate
the crosstalk matrix learning procedure for larger arrays of transmon qubits.
We observe an empirically linear scaling with system size, while maintaining a
median qubit frequency error below kHz
Leprosy post-exposure prophylaxis with single-dose rifampicin
_Objective:_ Leprosy post-exposure prophylaxis with single-dose rifampicin (SDRPEP) has proven effective and feasible, and is recommended by WHO since 2018. This SDR-PEP toolkit was developed through the experience of the leprosy postexposure prophylaxis (LPEP) programme. It has been designed to facilitate and standardise the implementation of contact tracing and SDR-PEP administration in regions and countries that start the intervention.
_Results:_ Four tools were developed, incorporating the current evidence for SDRPEP and the methods and learnings from the LPEP project in eight countries.
(1) th
Prevalence of dengue viral and malaria parasitic co-infections in an epidemic district, Angul of Odisha, India: An eco-epidemiological and cross-sectional study for the prospective aspects of public health
Summary: The co-existence of dengue and malaria infection in an individual and the primary and secondary dengue infection during co-infection were assessed. Over 1 year, 1980 blood samples were collected from suspected cases of dengue fever and analyzed by rapid diagnostic test (RDT), enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) methods to detect dengue infection. RDT and microscopic methods were used to detect malaria. Of the 1980 samples, only 22 (3.0%) cases were identified as dengue–malaria co-infection cases, out of which 13 were male and 9 were female. The highest number of confirmed cases were found during the hot and humid months of September and October (7 cases, 31.8%) and within the over 15 years age group. Of the cases of co-infection, dengue primary infection (21 cases, 95.5%) was significantly more common than dengue secondary infection (1 case, 4.5%) among all of the age groups. There were 12 cases of Plasmodium falciparum and 10 cases of Plasmodium vivax infection among malarial cases. A high prevalence of concurrence of dengue and malaria infection was recorded in this ecosystem. In light of the severity of co-infection and overlapping symptoms, a multidimensional diagnostic approach is suggested. Keywords: Dengue, Malaria, Co-infection, Surveillance, Odish