1,389 research outputs found

    Diagnosis and Management of Infantile Hemangioma

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    Infantile hemangiomas (IHs) are the most common tumors of childhood. Unlike other tumors, they have the unique ability to involute after proliferation, often leading primary care providers to assume they will resolve without intervention or consequence. Unfortunately, a subset of IHs rapidly develop complications, resulting in pain, functional impairment, or permanent disfigurement. As a result, the primary clinician has the task of determining which lesions require early consultation with a specialist. Although several recent reviews have been published, this clinical report is the first based on input from individuals representing the many specialties involved in the treatment of IH. Its purpose is to update the pediatric community regarding recent discoveries in IH pathogenesis, treatment, and clinical associations and to provide a basis for clinical decision-making in the management of IH

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    F. Robert Henderson et al., Increasing Eastern Bluebirds in Kansas, Kansas State University, November 1990

    Oxidative Stress Markers Are Associated with Persistent Atrial Fibrillation

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    Background:Atrial fibrillation (AF) has been associated with myocardial oxidative stress, and antioxidant agents have demonstrated antiarrhythmic benefit in humans. We compared serum markers of oxidation and associ-ated inflammation in individuals with or without AF. Methods: Serummarkers of oxidative stress and inflam-mation were compared in a cross-sectional, case-control design study of 40 male individuals, with or without persistent or permanent AF, who were matched for age, sex, diabetes, and smoking status, known confounding variables for the measurement of oxidative stress. We used derivatives of reactive oxidative metabolites (DROMs) and ratios of oxidized to reduced glutathione (Eh GSH) and cysteine (Eh CySH) to quantify oxidative stress. We also measured inflammatory markers, includ-ing high-sensitivity C-reactive protein, interleukins 1 and 6, and tumor necrosis factor . Results: Univariate, conditional logistical regression analysis showed that oxidative stress but not inflamma-tory markers were statistically associated with AF (P <0.05). The increase in the odds ratios for AF for E
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