Lung Cancer and Epigenetic Modifications | Akciğer Kanseri Ve Epigenetik Değişiklikler

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TOXICITY-CHEMISTRY RELATIONSHIPS IN SEDIMENTS COLLECTED FROM BLACK SEA

Abstract This research investigated the spatial distribution of chemical contamination and toxicity of marine surfacial sediments collected from six sites along the Turkish coast in Black Sea. Sediment toxicity to sea urchin (Paracentrotus lividus) embryonic development was evaluated with whole sediment specimens. Concurrently, sediment samples were analyzed for their chemical characterisation to evaluate toxicity data

Evaluation of liver damage after application of TVE in the rat model

WOS: 000234412900103PubMed: 16387167Introduction. The aim of this study was to investigate the effects of total vascular exclusion (TVE) on the liver during the early period of reperfusion. Materials and methods. Forty Wistar-Albino rats were divided into four groups. Portal pedicle clamping (groups 1 and 2) or TVE (groups 3 and 4) were applied for 10 minutes. Samples were collected at the time of clamp release (groups 1 and 3) and at 30 minutes of reperfusion (groups 2 and 4). We examined oxidative injury to and histopathology of the liver. Results. Oxidative stress was more prominent with TVE application. Significant alterations were shown in hepatic superoxide dismutase, catalase, glutathione, and glutathione S-transferase levels. The levels of malondialdehyde and myeloperoxidase were not altered significantly. Conclusion. Inflow-outflow occlusion of the liver causes more oxidative stress compared with inflow occlusion

Aliphatic and polycyclic aromatic hydrocarbons in the surface sediments from the Eastern Aegean: assessment and source recognition of petroleum hydrocarbons

Materials and methods Aliphatic and polycyclic aromatic hydrocarbons (PAHs) were determined in surficial sediments from the Aegean Sea in the Eastern Mediterranean in 2008. Results Total aliphatic hydrocarbons (n-C12 to n-C35) ranged from 330 to 2,660 ng g(-1) dry weight (dwt), while aromatics (19 PAHs) varied between 73.5 and 2,170 ng g(-1) dwt. Total concentrations of both aliphatic hydrocarbons and PAHs ranged from a relatively low to a moderate PAHs pollution compared to other urbanized coastal areas worldwide. PAH consisted mainly of pyrolytic four-to five-ring compounds. Both pyrolytic and petrogenic PAHs are present in most samples, although petroleum-derived PAH are dominant at Izmir Inner Bay (IIB) and Dardanelles Strait, and pyrolytic sources are prevalent in other sampling sites. A high contribution of perylene, a diagenetic originated PAH, to the total penta PAHs was found greater than 70% in Meric River Estuary, Dikili Bay, Candarli Bay, and Gokova Bay sites