Obesity: The Relationship between Growth Hormone and Exercises

Obesity is one of the main causes of death around the world. Moreover, considering the cardiometabolic risk (CMR), the relationship between obesity and CMR is well-established, and the location of adipose tissue (AT), particularly in the abdominal region, is considered an important predictor of metabolic dysfunction than total fat mass. Central obesity can be related to abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT). The relationship between SAT and CMR is not still clear, but the VAT has been considered a unique pathogenic fat depot. In this context, it is important to identify clinical interventions that could be used to improve the management of obesity. The aim of this chapter is to integrate knowledge about the relevance of exercises and/or growth hormone (GH) to the management of individuals with obesity. In conclusion, it appears that exercise-induced reductions in VAT are mediated by induced changes in GH levels. This could be due to the similar lipolytic effects of both GH and exercise on VAT and this relationship would benefit the role of exercise as an intervention against obesity. Preventing and understanding the development of obesity is therefore essential if it is wanted to curb the global epidemic and save social security several million costs concerning health problems

Impacts of COVID-19 Pandemic on Sleep Quality Evaluated by Wrist Actigraphy: A Systematic Review

COVID-19 has probably contributed as a risk factor for sleep disturbance. Actigraphy has been used to evaluate sleep complaints in self-isolated populations and frontline doctors during the COVID-19 pandemic. This systematic review aims to summarize the impact of the COVID-19 pandemic on sleep through wrist actigraphy, estimating sleep latency, total sleep time, awakening-after-sleep onset, and sleep efficiency. Searches were conducted of observational studies on the PubMed, Embase, Scopus, Web of Science, and PEDro databases from 1 December 2019 to 31 December 2022. Ninety articles were found, and given the eligibility criteria, fifteen were selected. Six studies were classified by the National Health and Medical Research Council as evidence level IV, two studies as level III-3, and seven studies as level III-2. According to the ACROBAT-NRSI instrument, three studies were classified as having a “serious” risk of bias, two as having “critical” risk, four as having “moderate” risk, and six as having “low” risk. In the selected publications, various populations were evaluated via actigraphy during the COVID-19 pandemic, with reports of “poor” sleep quality. Actigraphy may be a relevant tool to assess individual day–night rhythms and provide recommendations under enduring pandemic conditions. Moreover, as actigraphy presents objective data for sleep evaluations, it is suggested that this method be used in similar pandemics and that actigraphy be included as part of the sleep hygiene strategy