The Korean armistice of 1953 and its consequences - part I

Hoare: Both North and South Korea claim victory in the Korean War. Yet neither makes much of the ending of the war in July 1953, and both have had problems coming to terms with the reality of the war. The reality is that both suffered so much in a conflict that achieved little that formal celebrations seem inappropriate. Daniels: The outbreak of the Korean war in 1950 and the ferocious fighting which took place affected Britain, whose army took part in the war. This essay records the different shades of opinion expressed in its various newspapers/journals

The Korean Armistice of 1953 and its Consequences - Part I

Hoare: Both North and South Korea claim victory in the Korean War. Yet neither makes much of the ending of the war in July 1953, and both have had problems coming to terms with the reality of the war. The reality is that both suffered so much in a conflict that achieved little that formal celebrations seem inappropriate.Daniels: The outbreak of the Korean war in 1950 and the ferocious fighting which took place affected Britain, whose army took part in the war. This essay records the different shades of opinion expressed in its various newspapers/journals.Korea, Korean war, 1950, Korean armistice, commemoration, Britain, Japan, China, newspapers, museums, monuments.

Local origins of volume fraction fluctuations in dense granular materials

Fluctuations of the local volume fraction within granular materials have previously been observed to decrease as the system approaches jamming. We experimentally examine the role of boundary conditions and inter-particle friction $\mu$ on this relationship for a dense granular material of bidisperse particles driven under either constant volume or constant pressure. Using a radical Vorono\"i tessellation, we find the variance of the local volume fraction $\phi$ monotonically decreases as the system becomes more dense, independent of boundary condition and $\mu$. We examine the universality and origins of this trend using experiments and the recent granocentric model \cite{Clusel-2009-GMR,Corwin-2010-MRP}, modified to draw particle locations from an arbitrary distribution ${\cal P}(s)$ of neighbor distances $s$. The mean and variance of the observed ${\cal P}(s)$ are described by a single length scale controlled by $\bar \phi$. Through the granocentric model, we observe that diverse functional forms of ${\cal P}(s)$ all produce the trend of decreasing fluctuations, but only the experimentally-observed ${\cal P}(s)$ provides quantitative agreement with the measured $\phi$ fluctuations. Thus, we find that both ${\cal P}(s)$ and ${\cal P}(\phi)$ encode similar information about the ensemble of observed packings, and are connected to each other by the local granocentric model

Llamas in the Rockies

The use of llamas as pack animals in the United States is increasing in popularity. Llamas cause only light ecological impact, climb and jump well, and are easy to work with

Design of Experiments Using TMA WorkBench

TMA WorkBench software is used to interface with Suprem4 process simulator and Medici electrical test software in order to set up, run and analyze Design of Experiments for process simulation. A method for simulation tuning was found, and an example experiment was run and analyzed. Comparison to a fabricated experiment was planned in order to provide feedback for simulation tuning and to verify a simulated approach to process experimenting. Least squares analysis was used to find response function coefficients, as well as to plot factor-response contour maps

Certain Aspects of the Status of Instructional Television in Elementary and Secondary Schools in the State of Utah

The primary purpose of the study was to determine the level of teacher competence concerning instructional television and the need for university training for future teachers. The secondary purpose of the study was to determine the availability, accessibility and utilization of instructional television equipment in elementary and secondary schools in the State of Utah. The principals of 400 elementary and secondary schools were the respondents in this study. A questionnaire was designed to acquire information on the following: (1) What degree of sophistication and types of television equipment are presently available in schools in the State of Utah; (2) what major problems are encountered by teachers using television; and (3) are the universities in the state adequately preparing teachers in the use of instructional television as an instructional medium. The results of the survey suggest that universities should offer prospective teachers hands-on experience in television utilization and production. An overwhelming majority of school principals (91 percent) indicated that universities should be doing this job. The results indicated what type of and how much equipment Utah schools presently have. In addition the survey showed the type of productions and programs that teachers are presently doing with television equipment. The results also identified several specific problem areas teachers now have

Structural Remodeling Of Alpha-Synuclein By Small Molecules: A Novel Path To Neuroprotective Therapeutics

Neurodegenerative diseases share the unifying features of insoluble protein aggregates and irreversible neuron loss. Parkinson’s disease (PD) is defined by proteinaceous Lewy bodies—which contain α-synuclein—and loss of dopamine neurons leading to motor dysfunction. Growing evidence implicates α-synuclein aggregation as a causal driver of neurodegeneration in certain forms of PD. However, the precise mechanism(s) by which the process or products of α-synuclein aggregation drive neuron death remains unknown. Better understanding of this key question might further development of neuroprotective therapies for PD and related disorders. To address this gap, we reviewed how the native conformation of α-synuclein relates to its physiological function and roles in pathology. We also examined how the mouse brain proteome and phosphoproteome change in response to α-synuclein aggregation using quantitative proteomics. This revealed that proteomic changes were not widespread, but instead were enriched within certain functional areas. For the first time, we found that the immunoproteasome is induced during aggregation, providing a new tunable target for studying α-synuclein aggregation and its connection to toxicity. We also employed nordihydroguaiaretic acid (NDGA) and analogs to study the chemistry and products of phenolic inhibitors of α-synuclein aggregation. We discovered that oxidation-dependent cyclization is required for NDGA analogs to inhibit α-synuclein aggregation and that this inhibition is caused by modification of α-synuclein monomers that retain their conformational dynamics and lipid interactions. Further, we found that these NDGA analog-modified monomers exert a dominant negative effect on aggregation of untreated α-synuclein, exposing a novel mechanism for inhibiting α-synuclein aggregation. Using transgenic Caenorhabditis elegans, we showed that cyclized NDGA can prevent neurodegeneration driven by α-synuclein. These findings outline a novel paradigm for small molecule inhibition of α-synuclein aggregation wherein they act by stabilizing dynamic α-synuclein monomers, preventing aggregation. This in turn prevents aggregation of untreated α-synuclein and reduces neurodegeneration. Together this work underscores the importance of α-synuclein’s native structural dynamics and provides several novel tools for future use in untangling the relationship between α-synuclein aggregation and neuron loss in PD and related disorders

Forestry Club

The Forestry Club continued its traditional activities in the 1984-85 school year. Members attended the Midwestern Forestry Conclave at the University of Ohio. Christmas tree sales, the Annual Wild Game Banquet, Veisheas displays, Firesides with Faculty, and Firewood cutting at the Sate Nursery were other activities