Figure 7 shows the linear regression plot for SBP-Non DA and DBP-Non DA over time.

<p>Mean age related normal valued is plotted in relation to patient SBP-Non DA/DBP-Non DA values for comparison.</p

Figure 5 shows the mean SBP (mmHg) and DBP (mmHg) across 19 time points.

<p>For comparison, age specific normal measurements are included as the last measurement on the X-axis.</p

a–i.

<p>*Identifies statistically significant (p<0.05) differences between DA and Non-DA groups for the same time point (5a–i). + identifies statistically significant (p<0.05) differences within DA or Non-DA groups across time points (5a–i). T1 (6–12 hrs post admission); T2 (2–3 wks); T3 (3 months).</p

Figure 2 shows that the difference in MDT at T2 minus T1 for the patients identified with mitral DA.

<p>The magnitude of the difference was statistically smaller (Z = −3.2684; p = 0.0011 : T1 not shorter than T2) in the DA group patients implying abnormal adaptation to sinus tachycardia at T1.</p

Figure 9 shows mean DBP (mmHg) for groups DA or Non-DA across 19 time points.

<p>Age specific normal measurements are included as the last measurement on the X-axis.</p

Demographic data for 17 patients in data set.

*<p>Fisher's Exact chi-square analysis indicates a significant association between the Diastolic Abnormality and the African American race (p = 0.0319).</p

Comparative analysis for ECHO variables that had significant differences for all patients at T1 (6–12 hours post admission) vs T2 (2–3 weeks/ECHO baseline), (N = 17 patients).

*<p>Statistically significant results p<0.05.</p

Repeated Measures ANOVA results (F-ratio and probability) for cytokines with significant differences across time. T1 (6–12 hours post admission); T2 (2–3 weeks); T3 (3 months).

*<p>- Mean (T1) significantly different (p<0.05) from (T2) mean; ++ - Mean (T1) different (p<0.05) from mean cytokine baseline measurement (T3). N = 17 subjects.</p

Figure 1 shows that the difference in mitral E/A at T2 (Baseline) minus E/A at T1 (DKA) was significantly less (Z = −3.1115, p = 0.0019) for the group of 5 patients with DA at T1 compared to the other 12 patients.

<p>HRs were not different in these 5 patients compared to the other 12 patients at T1 or T2.</p