High-tech element availability for sustainable energy systems in the 21st century : The Iberian Pyrite Belt as a potential supplier

This work provides estimations on the future raw material demand for the thin-film photovoltaic (PV) elements indium, selenium, tellurium, germanium and gallium. Data calculation has been carried out on the basis of current energy and PV market outlooks. For indium, our calculation yields a maximum cumulative demand of 12 kilotons for the period from 2008 to 2030. The minimum demand for the same period is of 8 kilotons. Additionally, static depletion times for the elements in question have been determined. For indium, the static depletion time of 22 years shows that its supply is highly endangered, particularly if indium consumption for LCD and solar panel production stays on a high level or even increases. The situation for selenium, with a static depletion time of 53 years, is not much better. Therefore, in addition to recycling, the fundamental way to enhance material supply is through intensified exploration for mineral deposits. Such exploration could focus in promising areas, where high-technology elements are already known to exist in sulphide ore deposits, e.g. the Iberian Pyrite Belt (IPB), a metallogenic province known for its massive sulphide ore resources

New insights on the ultramafic intrusions surrounding the Kunene Anorthosite Complex (SW Angola) from gravity, magnetic and radiometric data [Abstract]

ABSTRACT: The Kunene Anorthosite Complex (KAC), located in SW Angola, is one of the largest anorthosite structures in the world. Dating from the Mesoproterozoic, its installation process is still not clear. Several mafic and ultramafic outcrops can be found surrounding the KAC. Once considered related with its emplacement, the study of these bodies may help us understand the history of this unique geological feature. While geochronological data show that they are synchronous, or possibly a bit younger, than the embedding granites and migmatites of Paleoproterozoic age, the question arises of whether they are intrusions installed in the host rock or if they are instead recycled remains of older Arch crust. The development of these outcrops in depth provides relevant clues regarding the origin of these bodies and their relationship with the Eburnean (~1.93-2.04 Ga) and Epupa-Namibe (~1.83-1.74 Ga) events. One of these mafic outcrops, designated the Hamutenha outcrop (Huíla Province) exhibits an elongated shape and a NW-SE orientation and is characterized by an internal zonation. Generally, the innermost part is composed of ultramafic rocks of (mostly harzburgites and dunites), with diorites outcropping in its NW and SE borders. The Hamutenha outcrop was previously identified for potentially bearing Cr, Ni and PGE mineralization.N/

Metallogenetic potencial of the Paleoproterozoic mafic-ultramafic Hamutenha intrusion (SW Angola). New data from PLANAGEO project [Abstract]

ABSTRACT: In the SW sector of the Angolan shield occur the Kunene Anorthositic Complex (KAC), one of the most remarkable magmatic anorthositic suites worldwide. The KAC is considered a long-lived magmatic system that operated in the area intermittently during the Mesoproterozoic (1450 ± 2 Ma to 1371 ± 2.5 Ma). Smaller mafic-ultramafic intrusive bodies ranging in composition from dunite to harzbugite, pyroxenite, troctolite and gabbro are located in the KAC periphery (e.g. Epupa, Ombuku, Hamutenha, Oncócua). The Hamutenha body is a 3 km long oriented NW-SE, banded intrusion with internal zonation hosted in the Paleoproterozoic granitic rocks (1970 ± 2 Ma). The internal zone is composed by rocks with ultramafic nature, mostly harzburgites and dunites with diorites in the external zone.N/

Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial

Background Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear. Methods RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047. Findings Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61–69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1–10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688–1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4–82·5) in the no ADT group and 80·4% (76·6–83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths. Interpretation Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population

Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial

Background Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain. Methods RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov , NCT00541047 . Findings Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60–69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0–10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612–0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6–75·7) in the short-course ADT group and 78·1% (74·2–81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths. Interpretation Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy. Funding Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society

Sparse Ultrasound Imaging via Manifold Low-Rank Approximation and Non-Convex Greedy Pursuit

Model-based image reconstruction has improved contrast and spatial resolution in imaging applications such as magnetic resonance imaging and emission computed tomography. However, these methods have not succeeded in pulse-echo applications like ultrasound imaging due to the typical assumption of a finite grid of possible scatterer locations in a medium–an assumption that does not reflect the continuous nature of real world objects and creates a problem known as off-grid deviation. To cope with this problem, we present a method of dictionary expansion and constrained reconstruction that approximates the continuous manifold of all possible scatterer locations within a region of interest. The expanded dictionary is created using a highly coherent sampling of the region of interest, followed by a rank reduction procedure. We develop a greedy algorithm, based on the Orthogonal Matching Pursuit, that uses a correlation-based non-convex constraint set that allows for the division of the region of interest into cells of any size. To evaluate the performance of the method, we present results of two-dimensional ultrasound imaging with simulated data in a nondestructive testing application. Our method succeeds in the reconstructions of sparse images from noisy measurements, providing higher accuracy than previous approaches based on regular discrete models

A Sparse Reconstruction Algorithm for Ultrasonic Images in Nondestructive Testing

Ultrasound imaging systems (UIS) are essential tools in nondestructive testing (NDT). In general, the quality of images depends on two factors: system hardware features and image reconstruction algorithms. This paper presents a new image reconstruction algorithm for ultrasonic NDT. The algorithm reconstructs images from A-scan signals acquired by an ultrasonic imaging system with a monostatic transducer in pulse-echo configuration. It is based on regularized least squares using a l1 regularization norm. The method is tested to reconstruct an image of a point-like reflector, using both simulated and real data. The resolution of reconstructed image is compared with four traditional ultrasonic imaging reconstruction algorithms: B-scan, SAFT, !-k SAFT and regularized least squares (RLS). The method demonstrates significant resolution improvement when compared with B-scan—about 91% using real data. The proposed scheme also outperforms traditional algorithms in terms of signal-to-noise ratio (SNR)

Effects of Thermal Gradients in High-Temperature Ultrasonic Non-Destructive Tests

Ultrasonic inspection techniques and non-destructive tests are widely applied in evaluating products and equipment in the oil, petrochemical, steel, naval, and energy industries. These methods are well established and efficient for inspection procedures at room temperature. However, errors can be observed in the positioning and sizing of the flaws when such techniques are used during inspection procedures under high working temperatures. In such situations, the temperature gradients generate acoustic anisotropy and consequently distortion of the ultrasonic beams. Failure to consider such distortions in ultrasonic signals can result, in extreme situations, in mistaken decision making by inspectors and professionals responsible for guaranteeing product quality or the integrity of the evaluated equipment. In this scenario, this work presents a mathematical tool capable of mitigating positioning errors through the correction of focal laws. For the development of the tool, ray tracing concepts are used, as well as a model of heat propagation in solids and an experimentally defined linear approximation of dependence between sound speed and temperature. Using the focal law correction tool, the relative firing delays of the active elements are calculated considering the temperature gradients along the sonic path, and the results demonstrate a reduction of more than 68% in the error of flaw positioning