663 research outputs found
Linear Logic for Meaning Assembly
Semantic theories of natural language associate meanings with utterances by
providing meanings for lexical items and rules for determining the meaning of
larger units given the meanings of their parts. Meanings are often assumed to
combine via function application, which works well when constituent structure
trees are used to guide semantic composition. However, we believe that the
functional structure of Lexical-Functional Grammar is best used to provide the
syntactic information necessary for constraining derivations of meaning in a
cross-linguistically uniform format. It has been difficult, however, to
reconcile this approach with the combination of meanings by function
application. In contrast to compositional approaches, we present a deductive
approach to assembling meanings, based on reasoning with constraints, which
meshes well with the unordered nature of information in the functional
structure. Our use of linear logic as a `glue' for assembling meanings allows
for a coherent treatment of the LFG requirements of completeness and coherence
as well as of modification and quantification.Comment: 19 pages, uses lingmacros.sty, fullname.sty, tree-dvips.sty,
latexsym.sty, requires the new version of Late
Mahlon Pitney and Caroline Pitney to Dalrymple Family, December 29, 1820
Legal Indenture from Mahlon Pitney, Samuel P. Dalrymple, John Dalrymple, Phebe Ann Dalrymple, and Frederick B. Dalrymple to Caroline Pitney for money due for Grays Hollow lot.
People Included: Samuel Pitney, James Pitney, Diziah Dalrymplehttps://digitalcommons.kean.edu/lhc_1820s/1140/thumbnail.jp
Behavioural Consequences of Frontal Cortex Grafts and Enriched Environments after Sensorimotor Cortex Lesions
Past studies have experienced difficulty in
achieving graft survival and behavioural
recovery after sensorimotor cortex lesions. In the
present work, adult female rats trained
preoperatively to cross a narrow beam for food
reward were maintained in standard group
cages or an enriched environment, commencing
one week after a unilateral lesion. One month
post-lesion, half of these rats received multiple
suspension grafts of (E20) fetal frontal cortex,
placed adjacent to the lesion cavity, and 8 days
later recovery of beam-walking skills was
examined for a six-week period. The grafts
survived in all cases with an appropriate lesion,
a notable result given the one month lesion-graft
delay, but graft volume was not influenced by
postoperative environment. The substantial
lesion-induced deficits evident just prior to
differential housing showed a marked reduction
by the start of post-graft testing, but relative to
intact controls a persistent deficit in foot slip
errors occurred in all lesion groups. Irrespective
of graft status, postoperative enrichment
prevented the occurrence of severe foot slips,
especially early in retraining. The frontal grafts,
however, enhanced beam-walking recovery by
reducing the overall frequency of foot slips on
early post-grafting sessions, an effect we suggest
is related to graft-derived trophic influences, but
this measure was not significantly improved by
postoperative enrichment
Self-Rated Distress Related to Medical Conditions is Associated with Future Crashes or Traffic Offences in Older Drivers
Ageing is associated with the development of medical conditions, both acute and chronic. The aim of this study was to determine whether medical factors were associated with subsequent self- and officially-reported crashes and traffic offences in a group of cognitively healthy older drivers. We surveyed medical conditions, medications taken for these conditions, and the amount of subjective distress associated with medical conditions in a group of 56 drivers aged 72-85 years for a period of 24 months. We also compared exposure to driving at baseline to the number of crashes or offences at 24 months. We found no relationship between the number of medical conditions or medications taken and whether a participant had a crash or offence. However, those who reported more subjective distress associated with their condition/s were more likely to have a crash or offence during the study period. Drivers who had a crash or offence also had a higher mean driving exposure. However, there was no relationship between reported distress and driving exposure which indicates that these may be independent risk factors for experiencing a crash or traffic offence
The thalamic reuniens is associated with consolidation of non-spatial memory too
The nucleus reuniens (RE) is situated in the midline thalamus and provides a key link between the hippocampus and prefrontal cortex. This anatomical relationship positions the Re as an ideal candidate to facilitate memory consolidation. However, there is no evidence that this role extends beyond spatial memory and contextual fear memory, which are both strongly associated with hippocampal function. We, therefore, trained intact male Long–Evans rats on an odor–trace–object paired-associate task where the explicit 10-s delay between paired items renders the task sensitive to hippocampal function. Neurons in the RE showed significantly increased activation of the immediate early gene (Zif268) when rats were re-tested for previous non-spatial memory 25 days after acquisition training, compared to a group tested at 5-days post-acquisition, as well as a control group tested 25 days after acquisition but with a new pair of non-spatial stimuli, and home cage controls. The remote recall group also showed relatively augmented IEG expression in the superficial layers of the medial PFC (anterior cingulate cortex and prelimbic cortex). These findings support the conclusion that the RE is preferentially engaged during remote recall in this non-spatial task and thus has a role beyond spatial memory and contextual fear memory
Prediction of Driving Ability in People With Dementia- and Non- Dementia-Related Brain Disorders
Brain disorders can impair physical and cognitive functions necessary for safe driving. Two hundred people with brain disorders referred for a driving assessment were recruited and their performance on a computerized battery of sensory-motor and cognitive tests (SMCTests) and a blinded on-road assessment determined. Based on SMCTests performance, binary logistic regression (BLR) and nonlinear causal resource analysis (NCRA) models classified on-road pass or fail with 70% accuracy. Greater accuracy could be achieved by splitting referrals into two groups: (1) Dementia and (2) Non-dementia-related brain disorders. BLR models classified on-road driving outcome as pass or fail with accuracies of 76% (Dementia) and 75% (Non-dementia), while NCRA models had accuracies of 77% (Dementia) and 80% (Non-dementia). Measures of attention were most critical for predicting driving ability in the dementia group. In the non-dementia group, prediction of driving ability was most accurate with assessment of a broader range of sensory-motor and cognitive functions. Compared to BLR, NCRA was able to identify and use additional measures to improve accuracy. NCRA is also better able to accommodate outliers due to it being a non-linear modelling method based upon individual performance-limiting impairments. We propose three main factors underlying sub-optimal prediction of driving ability based on SMCTests performance: (1) there are one or more functions important for driving ability which are not currently assessed with SMCTests – these could be sensory-motor or cognitive or other (e.g., attitude, confidence, insight, road code knowledge); (2) suboptimal classification/prediction techniques or models; or (3) inaccuracies in the on-road driving assessments
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