9 research outputs found
Myxoinflammatory fibroblastic sarcoma: report of a case and review of the literature
Myxoinflammatory fibroblastic sarcoma (MIFS) is a lowgrade
sarcoma generally arising in adults. We present a
case of MIFS in a 5-year-old boy with a palpable nodule
in the subcutaneous tissue of the scalp. We carried out a
literature review to evaluate the diagnostic patterns based
on histologic and cytologic features and possible pitfalls
and misdiagnoses. A systematic search for articles of
interest published between 1995 and 2011 was performed
in MEDLINE and PubMed using the words ‘‘myxoinflammatory
fibroblastic sarcoma,’’ ‘‘myxohyaline tumor,’’
and ‘‘inflammatory myxoid tumor.’’ Histology
and cytology have a pivotal role in the differential
diagnosis between MIFS and other potential soft-tissue
mimics, such as nodular and proliferative fasciitis and
inflammatory myofibroblastic tumor. Fine-needle aspiration
cytology is a safe and useful tool for the diagnosis of
pediatric patients with MIFS and is important for an
accurate and precise preoperative workup to optimize
subsequent management and treatment
Myxo-inflammatory Fibroblastic Tumor - Report of a Case and Review of the Literature.
Myxoinflammatory fibroblastic sarcoma (MIFS) is a low-grade sarcoma generally arising in adults. We present a case of MIFS in a 5-year-old boy with a palpable nodule in the subcutaneous tissue of the scalp. We carried out a literature review to evaluate the diagnostic patterns based on histologic and cytologic features and possible pitfalls and misdiagnoses. A systematic search for articles of interest published between 1995 and 2011 was performed in MEDLINE and PubMed using the words "myxoinflammatory fibroblastic sarcoma," "myxohyaline tumor," and "inflammatory myxoid tumor." Histology and cytology have a pivotal role in the differential diagnosis between MIFS and other potential soft-tissue mimics, such as nodular and proliferative fasciitis and inflammatory myofibroblastic tumor. Fine-needle aspiration cytology is a safe and useful tool for the diagnosis of pediatric patients with MIFS and is important for an accurate and precise preoperative workup to optimize subsequent management and treatmen