Exploration de methodes statistiques pour la comparaison de cartographies cerebrales. Application a l'etude des psychotropes

Available from INIST (FR), Document Supply Service, under shelf-number : TD 80549 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc

Tests d'hypothèses statistiques multidimensionnels pour l'étude des paramètres pharmaco-EEG

International audienc

A new tool for pharmaco-EEG and EPs mapping kinetics : the dynamic statistical decision tree (DSDT)

International audienc

A new tool for pharmaco-EEG and EPs mapping kinetics : the dynamic statistical decision tree (DSDT)

International audienc

Statistical Decision Tree: A Tool for Studying Pharmaco-EEG Effects of CNS-Active Drugs

International audienceQuantitative pharmaco-EEG has become a useful technique for determing pharmacodynamic parameters after CNS-active drug administration. Nevertheless, one of the most important problems faced by practitioners of pharmaco-EEG is the difficulty in evaluating drug-specific effects. In this article, a methodology for comparing two time sequences of pharmacodynamic measurements, the Statistical Decision Tree (SDT), is proposed. This methodology, based on one- and multi-dimensional Wilcoxon signed-rank tests on EEG variables, takes into account vigilance fluctuations and placebo effects in order to pick out effects specifically due to the drug