Medical Rehabilitation And Geriatric Depression Scale (GDS) Score In The Post Stroke Geriatric Patientsk E

Introduction: Post-stroke depression ranged between 11-68% depends on patient's diversity, diagnostic criteria, and duration between follow-ups after a stroke attack. Prevalence may increase due to the patient's age. Medical rehabilitation and psychotherapy are a necessary effort to help patients overcome their disability. Medical rehabilitation for post-stroke patients includes restoring body functions, handling comorbid dysfunction, exercising individual independence, increasing quality of life, and preventing stroke recurrence. Aim: The objective of this research is to look for the correlation between medical rehabilitation and GDS Score in post-stroke geriatric patients. Methods: This research is an analytical observational with 1 group cohort time approach. The population is post-stroke geriatric patients who go through medical rehabilitation in Primasatya Husada Citra Hospital Surabaya. Result: Using the Chi-Square Test, the value of p is 1. After two weeks of medical rehabilitation, this shows that there is no significant correlation between medical rehabilitation and changes in the GDS score in post-stroke geriatric patients. The value of the odds ratio is 2,333. Conclusion: there was no significant effect of medical rehabilitation on GDS scores in elderly patients after stroke

EFFECTS OF ACUTE STRESS DURATION ON THE RAT BRAIN MAST CELL ACTIVATION

Background. Stress of varying duration and types are known to affect the number and activation level of cerebral mast cells (MCs) via plasma CRH. Although MC number is known not to be increased in acute stress, elevated plasma CRH might still activate brain MCs. Objective. To investigate the effect of acute stress of incremental duration to the activation level of thalamic and hippocampal mast cells using elevated platform test to elicit stress in male Wistar rats. Methods. This research used randomized post-test only control group design with 4 control group of 30, 60, and 90 minute stress exposure. Mast cell activation of the regiotalamus and hippocampus is assessed by histomorphometrics. Results. In the hippocampus, we found a significant difference of MC activation between control and experimental groups (p=0.014; p<0.05) but not among the incremental duration of acute stress. However, MC activation was not different between control and experimental groups in the thalamus. Conclusion. Acute stress exposure increases MC activation without recruiting further MCs in specific cerebral region but the duration of acute stress itself does not affect the activation level