6 research outputs found

    Levels of aminotransferases and lactate dehydrogenase in pregnant and preeclampsia fetuses

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    Hyperprolactinemia is endocrinology disorder of the hypothalamus-pituitary axis-gonade which manifests with high reproductive menstrual disorders and infertility.The purpose of the paper was to analyze the incidence of menstrual reproductive disorders (amenorrhea, oligomenorrhea, polimenorrhea) and galacthorrhea in to hyperprolactinemia. Material and methods The study included 125 patients. In group N (with hyperprolactinemia) included 35 women with menstrual disorders, galactorrhea and infertility. In group K (with normoprolactinemia) included 90 women with menstrual disorders, galactorrhea and infertility. Results The incidence of hyperprolactinemia N group was 28 % (hyperprolactinemia = 44.77 ng/ml) compared with group K with 72 % incidence (Hyperprolactinemia=8.83 ng/ml), which is statistical significance p \u3c0.0001. Amanorrhea incidence N group was 25.71 % (prolactenemia=74.49 ng/ml) compared to group amanorrhea K values 5.56 % and frequency prolactenemia 14.22 ng/ml is with statistical significance p \u3c0.0001. Oligomenorrhea incidence N group was 20 % compared with the incidence of oligomenorrhea K groups with 7.78 % incidence. Polimenorrhea N group is presented with 11.43 % incidence compared with the group K with 3.33 % incidence. Galactorrhea shown incidence 34.29 % (prolactinemia =64.49 ng/ml) N group compared to the values of K group with the incidence of 3.33 % and (prolactenemia =15.06 ng/ml) that is with statistical signifikanc p \u3c0.0001. Statistical analyses are made through the paired t-test and unpaired t-test. Conclusion Menstrual disorders fertility (amenorrhea, oligomenorhea, polimenorrhea) and galactorrhea are measured with high incidence and statistical signifikance hyperprolactinemia compared with control group (normoprolactinemia)

    Level of Prolactin and Progesterone at normal Pregnancy

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    The aim of this study was to discuss the level of progesterone and prolactin during the development of normal pregnancy and determine the report of progesterone and prolactine level with pregnant women and non-pregnant women. Material and methods: In this study are included 60 women with normal pregnancy (group N) and 60 non-pregnant women (groups S). In both groups blood samples were taken from cubital veins and determination of progesterone and prolactin concentration. Group N (n= 60 ) was selected in prospective way by eliminating from the study all the patients with pregnancy pathology. Group S (n= 60) was selected in prospective way by eliminating from the study the pathology of endocrine system. Results: First results showed that the level of progesterone in significant way is raised during the pregnancy (t= t= 2.589, P=o.o406 p\u3c o.o5). Prolactin is raised in significant way during the development of pregnancy. (t= 3.174, p 0.0252, p\u3c 0.05 ). While comparing the progesterone values with pregnant and non-pregnant women, we have ascertained that the level of progesterone in significant way was higher with pregnant women (q= 10.707, p\u3c 0.001). While comparing the prolactin values with pregnant and non-pregnant women, we have ascertained that the level of prolactin in significant way was higher with pregnant women (q=11.451, P \u3c 0.001). Discussion: The level of progesterone is raised due to development of placenta during pregnancy and increase of fetal area of suprarenal gland of fetus. The level of prolactin during pregnancy is raised due to effective stimulated placental steroids, estrogens, and rilizing tiretrop hormone in hypothalamus on one side and due to presence of prolactin decidul during pregnancy. Conclude: We conclude that the level of prolactin and progesterone is raised in significant way during the development of pregnancy. The values of progesterone and prolactin at pregnancy are raised in significant way comparing with non-pregnant women

    Levels of aminotransferases and lactate dehydrogenase in pregnant and preeclampsia fetuses

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    Hyperprolactinemia is endocrinology disorder of the hypothalamus-pituitary axis-gonade which manifests with high reproductive menstrual disorders and infertility.The purpose of the paper was to analyze the incidence of menstrual reproductive disorders (amenorrhea, oligomenorrhea, polimenorrhea) and galacthorrhea in to hyperprolactinemia. Material and methods The study included 125 patients. In group N (with hyperprolactinemia) included 35 women with menstrual disorders, galactorrhea and infertility. In group K (with normoprolactinemia) included 90 women with menstrual disorders, galactorrhea and infertility. Results The incidence of hyperprolactinemia N group was 28 % (hyperprolactinemia = 44.77 ng/ml) compared with group K with 72 % incidence (Hyperprolactinemia=8.83 ng/ml), which is statistical significance p \u3c0.0001. Amanorrhea incidence N group was 25.71 % (prolactenemia=74.49 ng/ml) compared to group amanorrhea K values 5.56 % and frequency prolactenemia 14.22 ng/ml is with statistical significance p \u3c0.0001. Oligomenorrhea incidence N group was 20 % compared with the incidence of oligomenorrhea K groups with 7.78 % incidence. Polimenorrhea N group is presented with 11.43 % incidence compared with the group K with 3.33 % incidence. Galactorrhea shown incidence 34.29 % (prolactinemia =64.49 ng/ml) N group compared to the values of K group with the incidence of 3.33 % and (prolactenemia =15.06 ng/ml) that is with statistical signifikanc p \u3c0.0001. Statistical analyses are made through the paired t-test and unpaired t-test. Conclusion Menstrual disorders fertility (amenorrhea, oligomenorhea, polimenorrhea) and galactorrhea are measured with high incidence and statistical signifikance hyperprolactinemia compared with control group (normoprolactinemia)

    Level of prolactin and progesterone at normal pregnancy

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    The aim of this study was to discuss the level of progesterone and prolactin during the development of normal pregnancy and determine the report of progesterone and prolactine level with pregnant women and non-pregnant women. Material and methods: In this study are included 60 women with normal pregnancy (group N) and 60 non-pregnant women (groups S). In both groups blood samples were taken from cubital veins and determination of progesterone and prolactin concentration. Group N (n=60) was selected in prospective way by eliminating from the study all the patients with pregnancy pathology. Group S (n=60) was selected in prospective way by eliminating from the study the pathology of endocrine system. Results: First results showed that the level of progesterone in significant way is raised during the pregnancy (t=t=2.589, P=0.0406 p\u3c 0.05). Prolactin is raised in significant way during the development of pregnancy. (t=3.174, p 0.0252, p\u3c0.05 ). While comparing the progesterone values with pregnant and non-pregnant women, we have ascertained that the level of progesterone in significant way was higher with pregnant women (q=10.707, p\u3c0.001). While comparing the prolactin values with pregnant and non-pregnant women, we have ascertained that the level of prolactin in significant way was higher with pregnant women (q=11.451, P \u3c 0.001). Discussion: The level of progesterone is raised due to development of placenta during pregnancy and increase of fetal area of suprarenal gland of fetus. The level of prolactin during pregnancy is raised due to effective stimulated placental steroids, estrogens, and rilizing tiretrop hormone in hypothalamus on one side and due to presence of prolactin decidul during pregnancy. Conclude: We conclude that the level of prolactin and progesterone is raised in significant way during the development of pregnancy. The values of progesterone and prolactin at pregnancy are raised in significant way comparing with non-pregnant women

    The Study of Volume Density of Tracheal Ganglions In Vitro in New Born Babies with Respiratory Distress Syndrome

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    Volume density of respiratory organs was studied in vitro in newborn babies at different age of gestation (abort, immature, premature and mature) using stereometric method. The total of 23 cases was subject to this study. The respiratory organs (trachea, lungs) were taken from autopsies of newborn babies exited from different causes. For this purpose the tissues were fixed in formalin (10%) solution, cut serially in 7μ and 10μ slabs. Volume density of the respiratory system was assessed stereometricaly using Universal testing system Weibel M 42. We observed that volume density of epithelia, musculature and glands were proportionally present in the tracheal tissue. Cellular interstitial tissue is consistently increasing and corresponds to the developmental stages of the newborn babies. The density of tracheal ganglions is greater in premature ages of immature and premature newborns (p<0,05). Decreased number of ganglion cells is observed in mature ages (p<0,05). This is caused by intensive ramification of ganglions from serosa to deeper layers of trachea right to epithelium. Medium diameter of tracheal ganglions is greater in mature newborn babies and corresponds to developmental ages of babies

    The Study of Volume Density of Tracheal Ganglions In Vitro in New Born Babies with Respiratory Distress Syndrome

    Full text link
    Volume density of respiratory organs was studied in vitro in newborn babies at different age of gestation (abort, immature, premature and mature) using stereometric method. The total of 23 cases was subject to this study. The respiratory organs (trachea, lungs) were taken from autopsies of newborn babies exited from different causes. For this purpose the tissues were fixed in formalin (10%) solution, cut serially in 7μ and 10μ slabs. Volume density of the respiratory system was assessed stereometricaly using Universal testing system Weibel M 42. We observed that volume density of epithelia, musculature and glands were proportionally present in the tracheal tissue. Cellular interstitial tissue is consistently increasing and corresponds to the developmental stages of the newborn babies. The density of tracheal ganglions is greater in premature ages of immature and premature newborns (p<0,05). Decreased number of ganglion cells is observed in mature ages (p<0,05). This is caused by intensive ramification of ganglions from serosa to deeper layers of trachea right to epithelium. Medium diameter of tracheal ganglions is greater in mature newborn babies and corresponds to developmental ages of babies
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