9 research outputs found
Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics
- Author
- A Antczak
- A Bellmeyer
- A Bouloumie
- A Katsuki
- AH Stanley
- AJ Gow
- CA Camargo Jr.
- CC Thomson
- DWG KM
- E Baraldi
- E Luder
- E von Mutius
- EF Juniper
- F Dong
- FP Xu
- GE Carpagnano
- H Urakawa
- I Horvath
- J Beltowski
- J Shen
- JC Celedon
- JF Keaney Jr.
- JS Brenner
- KG Tantisira
- KW Tsang
- MJ Akerman
- MY Liu
- N Ouchi
- P Montuschi
- PF Belamarich
- R Barros
- R Varraso
- S Engeli
- S Hattori
- S Loffreda
- S Nakanishi
- S Shore
- SA Shore
- SA Shore
- T Ronti
- TA Nguyen
- TF Leung
- V Cassol
- W Nystad
- WS Beckett
- Y Chen
- Y Hattori
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
BACKGROUND: Recently, it has been shown that increasing body mass index (BMI) in asthma is associated with reduced exhaled NO. Our objective in this study was to determine if the BMI-related changes in exhaled NO differ across asthmatics and controls, and to determine if these changes are related to increased airway oxidative stress and systemic levels of leptin and adiponectin. METHODS: Observational study of the association of BMI, leptin, and adiponectin with exhaled nitric oxide (NO) and exhaled 8-isoprostanes in 67 non-smoking patients with moderate to severe persistent asthma during baseline conditions and 47 controls. Measurements included plasma levels of leptin, adiponectin, exhaled breath condensates for 8-isoprostanes, exhaled NO, pulmonary function tests, and questionnaires regarding asthma severity and control. RESULTS: In asthmatics, BMI and the ratio of leptin to adiponectin were respectively associated with reduced levels of exhaled NO (β = -0.04 [95% C.I. -0.07, -0.1], p < 0.003) and (β = -0.0018 [95% C.I. -0.003, -0.00034], p = 0.01) after adjusting for confounders. Also, BMI was associated with increased levels of exhaled 8-isoprostanes (β = 0.30 [95% C.I. 0.003, 0.6], p = 0.03) after adjusting for confounders. In contrast, we did not observe these associations in the control group of healthy non-asthmatics with a similar weight distribution. CONCLUSION: In adults with stable moderate to severe persistent asthma, but not in controls, BMI and the plasma ratio of leptin/adiponectin is associated with reduced exhaled NO. Also, BMI is associated with increased exhaled 8-isoprostanes. These results suggest that BMI in asthmatics may increase airway oxidative stress and could explain the BMI-related reductions in exhaled NO
Potential nanotechnologies and molecular targets in the quest for efficient chemotherapy in ovarian cancer
- Author
- Publication venue
- 'Informa Healthcare'
- Publication date
- Field of study
History of drugs for thrombotic disease. Discovery, development, and directions for the future.
- Author
- Bell RG
- Biedl A
- Binder BR
- Brinkhous KM
- Butt HR
- Campbell HA
- Chargaff E
- Chazov EL
- Crafoord C
- Craven LL
- Craven LL
- Craven LL
- Dam H
- Dastre A
- Fletcher AP
- Fletcher AP
- Godlowski Z.
- Howell WH
- Howell WH
- Howell WH
- Huebner CF
- ISIS-2 Collaborative Group
- Link KP
- Magnusson JH
- Mason EC
- Mason EC
- Milstone H
- Murray DWG
- Nichol ES
- Prandoni A
- Quick AJ
- Reed CI
- Reinert M
- Rijken DC
- Roderick LM
- Sahli W
- Schmidt-Mulheim A
- Schofield FW
- Sherry S
- Silver JM
- Sobel GW
- Stahmann MA
- The Coronary Drug Project Research Group
- von Brucke E
- Wilander 0
- Williams JRB
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- Field of study
PRESYNAPTIC RECEPTORS
- Author
- Alkondon M
- Bleakman D
- Boehm S
- Boland LM
- Budai D
- Capogna M
- Caterina MJ
- Coggan JS
- Collingridge GL
- Dittman JS
- Doze VA
- Frank K
- Gerau RW
- Graham B
- Kretz R
- Kulak JM
- Lena C
- Lena C
- Leveque C
- Matthews G
- McMahon LL
- McQuision AR
- Miller RJ
- Miller RJ
- Minchin MC
- Nicola SM
- Nicoll RA
- Page KM
- Ponce A
- Qian J
- Rangwala F
- Reid CA
- Reltig J
- Scholz KP
- Scholz KP
- Segev I
- Seguela P
- Sharp DWG
- Shekter LR
- Simmons ML
- Toth PT
- Trudeau LE
- Ullrich S
- Verrino S
- Whiting PJ
- Wilk-Blaszczak MA
- Wilk-Blaszczak MA
- Wiser O
- Wu L-G
- Wu LG
- Yokoyama CT
- Zhang SJ
- Publication venue
- 'Annual Reviews'
- Publication date
- Field of study
4.1 Cytoplasmic Glycolytic Enzymes. Synaptic Vesicle-Associated Glycolytic ATP-Generating Enzymes: Coupling to Neurotransmitter Accumulation
- Author
- A De Mendonca
- A Ikemoto
- A Sidhu
- A Spuler
- AA Rogalski-Wilk
- AC Dolphin
- AC Dolphin
- AH Schapira
- AJ Sommerfield
- B Dirks
- B Levy
- BK Siesjo
- C Masters
- CD Hardin
- CN Raffin
- CW Cotman
- CW Cotman
- D Ben-Shachar
- D Sulzer
- DG Bole
- DG Nicholls
- DJ Rossi
- DK Srivastava
- DW Choi
- DWG Cox
- DWG Cox
- EC McNay
- ED Ozkan
- EE Bellocchio
- EL Roberts Jr
- F Fonnum
- F Proverbio
- GE Gibson
- GE Gibson
- GL Collingridge
- GM Shepherd
- GR Siggins
- H Wolosker
- H Yawo
- HG Glitsch
- HR Knull
- HR Knull
- HS Bachelard
- IA Silver
- J Emerit
- J Lotharius
- J Lotharius
- JBG Ghajar
- JC Fowler
- JC Fowler
- JC Parker
- JC Watkins
- JD Campbell
- JH James
- JJ Laschet
- JL Pyle
- JN Lorenz
- JN Weiss
- JN Weiss
- JO Holloszy
- JP Weber
- JS Tabb
- JS Tabb
- JW Hell
- K Ogita
- K Wu
- KM Baldwin
- KP Scholz
- KY Xu
- L Sokoloff
- L-G Wu
- LD Lewis
- LM Berenski
- LMG Heilmeyer Jr
- M Schlaefer
- M Segal
- MF Beal
- MW Fleck
- MW Roe
- N Deutsch
- NJ Allen
- P Jenner
- P Lipton
- P Wang
- PO Okonkwo
- PR Dunkley
- PR Maycox
- PR Maycox
- PT Fox
- R Mager
- RJ Paul
- RJ Paul
- RJ Reimer
- RM Lynch
- RS Balaban
- RW Mercer
- S Naito
- S Naito
- S Shoji
- S Takamori
- SL Schrier
- T Kanatani
- T Ueda
- T Ueda
- TS Otis
- U Christians
- UK Laemmli
- VA Losito
- W Dauer
- WJ Nicklas
- Y Mizuno
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Pharmacokinetics
- Author
- A Angeli
- A Hughes
- A Jori
- A Reinberg
- A Reinberg
- A Reinberg
- A Reinberg
- A Reinberg
- A Reinberg
- A Schuna
- A Traeger
- A Wallin
- A Wirz-Justice
- AAH Lawson
- AC Deka
- AH Mackenzie
- AJ Levi
- AJ Taggart
- AK Shastri
- AL Makela
- AR Ford
- AS Nies
- AWS Ritchie
- BD Gupta
- CM Castleden
- Co-operating Clinics Committee of the American Rheumatism Association
- DAH Lee
- DAP Evans
- DAW Johnson
- DC Harrison
- DC Hobbs
- DE Duggan
- DL Scott
- DM Grennan
- DWG Harron
- E Karlsson
- E Rubin
- E Steiness
- EC Huskisson
- EC Huskisson
- Editorial
- EJ Triggs
- EP Gall
- EW McChesney
- F Bachmann
- F Bochner
- F Sereni
- F Sjoqvist
- FM Radzialowski
- G Alvan
- G Levy
- G Levy
- G Levy
- GA Beller
- GA Ewy
- GAO Alleyne
- GD Johnston
- GM Lees
- H Bernstein
- H Turakka
- HA Bird
- HM Perry
- HMA Taggart
- I Odar-Cederlof
- I Sjoholm
- IC Kowanko
- IC Kowanko
- J Aarbakke
- J Clench
- J Crooks
- J English
- J Koch-Weser
- J Koch-Weser
- J Lansbury
- J Rossum van
- JAL Harkness
- JB Whitlam
- JF Cumming
- JJ Misiewicz
- JJ Walshe
- JR Cove-Smith
- JR DeAndrade
- JR Koup
- JR Mitchell
- JR Mitchell
- JR Salaman
- JS Reeback
- JT Scott
- JW Jenne
- K Heilmann
- K Krishnaswamy
- K Krishnaswamy
- KC Kwan
- KJ Ivey
- KM Das
- KRH Adams
- L Pollmann
- LE Scheving
- LF Prescott
- LF Prescott
- LG Patel
- M Bardare
- M Gautherie
- M Gibaldi
- M Keeri-Szanto
- M Orme
- M Orme
- M Silva De
- MA Medina
- MG McGeown
- MH Smolensky
- MJ Dew
- MM Reidenberg
- MS Knapp
- MS Knapp
- N Baber
- NN Huang
- OC Green
- P Crosland-Taylor
- P Souich du
- PF Binnion
- PL Morselli
- PL Morselli
- PS Misra
- RA Branch
- RB Schoene
- RC Gerber
- RC Hamdy
- RE Schneider
- RE Schneider
- RE Vestal
- RF Bergstrom
- RH Briant
- RH Reuning
- RO Day
- RP Kimberly
- RP Kimberly
- S Riegelman
- SS Adams
- SY Tan
- T Nichols
- TRD Shaw
- TW Smith
- U Klotz
- V Wright
- VC Neumann
- VJM DiMaio
- W Blum
- W Hrushesky
- WD Heizer
- WH Lyle
- WS Nimmo
- WW Buchanan
- Y Touitou
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1986
- Field of study
Linking genomics and fish conservation decision making: a review
- Author
- A Shafer
- A Toussaint
- ABA Shafer
- AGP Ford
- AH Arthington
- AJ Couch
- AN Black
- AN Kadykalo
- AR Mahon
- B Arnold
- BA Garner
- BC Hecht
- BJ McMahon
- BM Fitzpatrick
- BP Olds
- C Walters
- CC Steiner
- CD Waters
- CH Martin
- CH Martin
- CJ Brauer
- CN Cook
- CR Primmer
- CS Goldberg
- DA Bell
- DE Ruzzante
- DJ Fraser
- DJ Prince
- DJ Schmidt
- DM Lodge
- DWG Stanton
- E Jakubavičiūtė
- ECM Parsons
- EG Mandeville
- EV Todd
- EW Malone
- F Maroso
- F Valenzuela-Quinonez
- FW Allendorf
- G Leroy
- G Ziervogel
- H Seebens
- HA Lewin
- HR Taylor
- I Montes
- IK Saglam
- J Bakker
- J Link
- JA Hamilton
- JE Hess
- JM Chapman
- JN Rinne
- JV Wells
- K Deiner
- KA Harrisson
- KD Balasingham
- Ken M. Jeffries
- KM Jeffries
- KW Wellband
- KW Wellband
- L Bernatchez
- L Bernatchez
- LA Dietz
- LK Campbell
- LR Nathan
- M Di Marco
- M Kardos
- M Simmons
- M Sinclair-Waters
- M Sinclair-Waters
- MC Lemos
- MC Yates
- MG Reed
- MH Hallfores
- MR Bangs
- MR Gaither
- MV Bravington
- MW Schwartz
- NC Kruck
- Nicholas E. Mandrak
- O Rey
- P Beerli
- P Hohenlohe
- PF Thomsen
- PM Grewe
- R Frankham
- RE Connon
- RG Gustafson
- RM Hillary
- RM Lew
- RP Kovach
- RS Waples
- S Hendricks
- S Hook
- S Wright
- SE Hook
- SJ Buckley
- SJ Cooke
- SJ Landsman
- SP Flanagan
- SR Browning
- TC Glenn
- ThaĂŻs A. Bernos
- U Laconcha
- VM Nguyen
- WC Funk
- WC Funk
- X He
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Cardiovascular Activity
- Author
- A Baartscheer
- A Baartscheer
- A Baartscheer
- A Bachmann
- A Bauer
- A Bergdahl
- A Bezold von
- A Biedl
- A Bomzon
- A Bonnacrossi
- A Braillon
- A Brkovic
- A Brueggemann
- A BrĂĽggemann
- A Bucchi
- A Capri
- A Carmeliet
- A Carotenuto
- A Cavalié
- A Cavalli
- A Chatelier
- A Chu
- A Claing
- A Daugherty
- A Daugherty
- A Daugherty
- A Ezzaher
- A Fabiato
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Fleckenstein
- A Gagliardi
- A Genao
- A Genovese
- A Gibson
- A Gibson
- A Gibson
- A Goll
- A Grassegger
- A Graziani
- A Grollman
- A Haugan
- A Hedberg
- A Helman
- A Hilditch
- A Hilditch
- A Hilditch
- A Hislop
- A Hislop
- A Hutchaleelaha
- A Inoue
- A Inoue
- A Inoue
- A Jarisch
- A Jarisch
- A Jarisch
- A Karlin
- A Kasai
- A Kochhar
- A Lerman
- A Lopez de Leon
- A Luchner
- A Luchner
- A LĂĽckhoff
- A LĂĽckhoff
- A Malhotra
- A Marchese
- A Marjamäki
- A Marmarou
- A Mattes
- A McRae
- A Menargues
- A Miwa
- A Molteni
- A Molteni
- A Molteni
- A Molteni
- A Monopoli
- A Morita
- A MĂĽlsch
- A Nygren
- A Osajima
- A Reaux
- A Reaux
- A Rudolph
- A Rutledge
- A Salimbeni
- A Sanbe
- A Sattin
- A Schuster
- A Schömig
- A Sculptoreanu
- A Sgoifo
- A Shiroshita-Takeshita
- A Stirrat
- A Sunami
- A Tajima
- A Tamura
- A Terzic
- A Tzanidis
- A Vacca
- A Vacca
- A Vaille
- A Vegh
- A Vegh
- A Verma
- A Volovsek
- A Wahhab
- A Ward
- A Wollenberger
- A Woppmann
- A Wright
- A Yu
- AA Andreadis
- AA Kochegarow
- AA Owji
- AA Pieper
- AB Fawzi
- AB Schreiber
- AB Schreiber
- AB Steffens
- AC Chiou
- AC Dolphin
- AC MacKinnon
- AC MacKinnon
- AC Sulpizio
- ACG Uprichard
- ACG Uprichard
- AD Medhurst
- AD Michel
- AD Michel
- AD Muskett
- AD Muskett
- AE Busch
- AE Busch
- AE Freedlender
- AE RiberoMO
- AEFH Meijer
- AF Green
- AF Green
- AF Green
- AF Green
- AF Green
- AF Odell
- AF Prigent
- AF Prigent
- AG Ciplea
- AGB Kovâch
- AH Cohen
- AH Gradman
- AH Nielsen
- AH Werber
- AH Weston
- AI Faden
- AI Faden
- AI Khan
- AIM Al-Shafei
- AIM Al-Shafei
- AJ Balmforth
- AJ Bold De
- AJ Carter
- AJ Carter
- AJ D’Alonzo
- AJ Gower
- AJ Gower
- AJ Hutchinson
- AJ Kaumann
- AJ Kielblock
- AJ King
- AJ Newell
- AJ Nichols
- AJ Pijl
- AJ Rice
- AJ Susswein
- AJ SzentmiklĂłsi
- AJ Trapani
- AJ Turner
- AK Fouda
- AK Ommaya
- AK Salyers
- AL Blatz
- AL Boura
- AL Golding
- AL Hudson
- AL Hyman
- AL Kwan
- AL Leoni
- AL Perraud
- AL Pichard
- AL Rothaul
- ALA Boura
- AM Al-Obaid
- AM Al-Obaid
- AM Babic
- AM Babic
- AM Beaufort
- AM Broadhurst
- AM Doherty
- AM Duncan
- AM Ehrly
- AM Feldman
- AM Feldman
- AM Gomez
- AM Hackett
- AM Joussen
- AM Lands
- AM Lands
- AM Lands
- AM Lands
- AM Oliveira
- AM Peier
- AM Peier
- AM Romanic
- AM Vineberg
- AM Watson
- AMB Bilate
- AMD Watson
- AN Santos
- AP Albert
- AP Davenport
- AP Ijzerman
- AP Moreno
- AR Dehpour
- AR Hosseini
- AR Liss
- AR Renzetti
- AR Renzetti
- AR Renzetti
- AR Shipolini
- AS Belloni
- AS Bhargava
- AS Harris
- AS Harris
- AS Manning
- AT Beggah
- AT Birmingham
- AT Byrne
- AT Chiu
- AT Chiu
- AT Chiu
- AT Chiu
- AT Chiu
- AT Chiu
- AT Chuang
- AT Chuang
- AT Chui
- ATZ Najbar
- AU ScholzW
- AU ScholzW
- AU ScholzW
- AU Trendelenburg
- AV Gryaznova
- AW Gomoll
- AW Gomoll
- AW Richardson
- AY Jeng
- AY Jeng
- AYW Chang
- B Anner
- B Badio
- B Chevalier
- B Christophe
- B Desta
- B Dieguez
- B Elger
- B Elger
- B Enholm
- B Faddis
- B Folkow
- B Garthoff
- B Garthoff
- B Gotti
- B Gout
- B Gout
- B Gouyon
- B Gumusel
- B Gumusel
- B Halliwell
- B Holmborn
- B Kisch
- B Kumar
- B Kumar
- B Lacombe
- B Lemmer
- B Lemmer
- B Lemmer
- B Lintschinger
- B Malinowska
- B Martin-McNulty
- B Masri
- B Masri
- B Meyrick
- B Meyrick
- B Meyrick
- B Meyrick
- B MĂĽller
- B Nilius
- B Nilius
- B Nilius
- B O’Rourke
- B Peruche
- B Rubin
- B Rubin
- B Sakmann
- B Surawicz
- B Tantini
- B Vannier
- B Vannier
- B Waldeck
- B Wiegershausen
- B Zander
- BA MacLeod
- BA Nassar
- BA Scholkens
- BA Scholkens
- BA Schölkens
- BA Schölkens
- BA Schölkens
- BA Schölkens
- BA Valentine
- BB Clark
- BB Fredholm
- BB Fredholm
- BB Fredholm
- BB Fredholm
- BB Hoffman
- BB Kenny
- BB Wolfe
- BC Knollmannn
- BC Wexler
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- BD Hoit
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- BE Osborn
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- BH Ackerman
- BH Choi
- BH Graham
- BJ DeWitt
- BJ DeWitt
- BJ DeWitt
- BJ Hoiycross
- BJ Scherlag
- BJ Walkden
- BK Bhattacharya
- BK Bhattacharya
- BL Partridge
- BM Abbott
- BM Kenyon
- BM Massie
- BM Olivera
- BN Dardik
- BP Bean
- BP Brockway
- BP Brockway
- BP Roques
- BR Duce
- BS Brown
- BS Pallotta
- BV Vargaftig
- BW Zweifach
- BZ Peterson
- BZ Peterson
- C Advenier
- C BackhauĂź
- C Banfi
- C Basso
- C Baylis
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- C Du
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- C Gabriel
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- C Gocmen
- C Gonzalez
- C Gros
- C Guiol
- C Harteneck
- C Hartzeneck
- C Helmle-Kolb
- C Hoffmann
- C Hornig
- C Huraux
- C Iadecola
- C Lacour
- C Lacour
- C Lind van Wijngaarden de
- C Lind van Wijngaarden de
- C Llorens
- C Lugnier
- C Lugnier
- C Luongo
- C Luongo
- C Maertens
- C Mathes
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- C Methfessel
- C Montell
- C Montell
- C Montell
- C Mourre
- C Mourre
- C Mukherjee
- C Mukherjee
- C MĂ©senge
- C Nathan
- C Pimoule
- C Raper
- C Richter
- C Rommel
- C Roza
- C Sardet
- C Schmitz
- C StrĂĽbing
- C SzabĂł
- C SzabĂł
- C Thiemermann
- C Thollon
- C Thollon
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- CB Ernst
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- CJ Young
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- CL Lin
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- CP Robinson
- CR Cory
- CR Hiley
- CS Barr
- CS Bockman
- CS Roberts
- CS Sweet
- CS Sweet
- CS Thompson
- CS Thompson
- CV Comiter
- D Angersbach
- D Ashton
- D Atlas
- D Atlas
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- D Ribatti
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- D Scherf
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- D Smart
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- D VanCalker
- D Wang
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- D Xu
- DA Calhoun
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- Wienen W Hauel N, van Meel JCA, Narr B, Ries U, Entzeroth M (1993) Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277. Br J Pharmacol 110:245–252 Wong PC, Quan ML, Saye JAM, Bernard R, Crain EJ Jr, Nc- Call DE, Watson CA, Zaspel AM, Smith RD, Wexler RR, Timmermans PBMWM, Chiu AT
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study