11 research outputs found

    Automated structure elucidation of two unexpected products in a reaction of an alpha,beta-unsaturated pyruvate.

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    The reaction between an alpha,beta-unsaturated pyruvate and ethyl diazoacetate (EDA) yielded two unexpected products. The structures of these products were determined by automated elucidation of the chemical structures using spectroscopic inputs of a series of 1D and 2D NMR data using the computer program ACD/Structure Elucidator, StrucEluc. The formation of these products is rationalised. Their structures were also confirmed by x-ray crystallography

    Characterization of biochemical markers of blood-brain-barrier permeability and the functioning of the central nervous system

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