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Isolation and characterization of a light chain variable region gene for human rheumatoid factors.
Previously, we isolated a Vk gene (Humkv325) from a human placenta that encodes RF light chains bearing the PSL2 and PSL3 CRI markers. Here we report the isolation and characterization of a second human Vk gene (Humkv328) that can be used for RF synthesis. This Vk gene probably encodes at least two 6B6.6 CRI+ RF light chains (Les and Pom) from unrelated subjects, and thus may be related to the light chain-associated 6B6.6 CRI
A case report of intracranial vertebral-basilar artery hypoplasia presenting with episodic dizziness
Basilar artery hypoplasia (BAH) is usually accompa-nied with unilateral vertebral artery hypoplasia (VAH); however, BAH with bilateral VAHs composing verte-bral-basilar artery hypoplasia (VBAH) is indeed a rare curiosity. A 61-year-old woman presented with epi-sodic dizziness for ten years. It accompanied with headache, bilateral tinnitus and blurred vision. Time-of-flight magnetic resonance angiogram with T2 true fast imaging in steady state precession confirmed the VBAH, rather than a stenosis. Symptoms subsided after daily oral aspirin and life-style change has been recommended for three months. The following one year was uneventful, and hearing improved. Finally, we conclude that the episodic dizziness with sensori-neural hearing impairment might attribute to the VBAH. It appears that life-style change was the main therapy and the antiplatelet was simply a supplementary on
Light Hadron Spectroscopy and Decay at BESIII
Light hadron spectroscopy plays an important role in understanding the decay
dynamics of unconventional hadronic states, such as strangeonium and glueballs.
BESIII provides an ideal avenue to search for these exotic states thanks to a
huge amount of data recorded at various energy points in the tau-charm mass
region including J/psi resonance. This report summarizes recent results of the
BESIII experiment related to the glueballs and strangeonium-like states.Comment: 6 pages, 5 figures, Conference proceeding of FPCP-201
Intensified Arctic warming under greenhouse warming by vegetation–atmosphere–sea ice interaction
Observations and modeling studies indicate that enhanced vegetation activities over high latitudes under an elevated CO2 concentration accelerate surface warming by reducing the surface albedo. In this study, we suggest that vegetation-atmosphere-sea ice interactions over high latitudes can induce an additional amplification of Arctic warming. Our hypothesis is tested by a series of coupled vegetation-climate model simulations under 2xCO(2) environments. The increased vegetation activities over high latitudes under a 2xCO(2) condition induce additional surface warming and turbulent heat fluxes to the atmosphere, which are transported to the Arctic through the atmosphere. This causes additional sea-ice melting and upper-ocean warming during the warm season. As a consequence, the Arctic and high-latitude warming is greatly amplified in the following winter and spring, which further promotes vegetation activities the following year. We conclude that the vegetation-atmosphere-sea ice interaction gives rise to additional positive feedback of the Arctic amplification.open1188sciescopu
Absorbate-Induced Piezochromism in a Porous Molecular Crystal
Atmospherically stable porous frameworks
and materials are interesting
for heterogeneous solid–gas applications. One motivation is
the direct and selective uptake of pollutant/hazardous gases, where
the material produces a measurable response in the presence of the
analyte. In this report, we present a combined experimental and theoretical
rationalization for the piezochromic response of a robust and porous
molecular crystal built from an extensively fluorinated trispyrazole.
The electronic response of the material is directly determined by
analyte uptake, which provokes a subtle lattice contraction and an
observable bathochromic shift in the optical absorption onset. Selectivity
for fluorinated absorbates is demonstrated, and toluene is also found
to crystallize within the pore. Furthermore, we demonstrate the application
of electronic structure calculations to predict a physicochemical
response, providing the foundations for the design of electronically
tunable porous solids with the chemical properties required for development
of novel gas-uptake media
Investigating the Capability of Precision in Robotic Grinding
Most robotic grinding focus on the surface finish rather than accuracy and precision. However ever increased demand on complex component manufacture requires to advance robot grinding capability so that more practical and competitive accurate systems can be developed. The current study focuses on improving the level of accuracy of robotic grinding, which is a significant challenge in robot application because the kinematic accuracy of robot movement is much more complex than normal CNC machine tools. Aiming to improve accuracy and efficiency the work considers all quality of measures including surface roughness and the accuracy of size and form. For that to be done, a repeatability test is firstly preformed to observe the distributions of the joint positions and how well the robot responds to its programmed position using a dial gauge method and a circuit trigger method. After that, a datum setting method is performed to assess the datum alignment with the robot. Hence, a mathematical model based on regression analyses applies towards the collected data to observe closely any error correlation when setting up a datum to perform the grinding procedure
Necessary and sufficient conditions of solution uniqueness in minimization
This paper shows that the solutions to various convex minimization
problems are \emph{unique} if and only if a common set of conditions are
satisfied. This result applies broadly to the basis pursuit model, basis
pursuit denoising model, Lasso model, as well as other models that
either minimize or impose the constraint , where
is a strictly convex function. For these models, this paper proves that,
given a solution and defining I=\supp(x^*) and s=\sign(x^*_I),
is the unique solution if and only if has full column rank and there
exists such that and for . This
condition is previously known to be sufficient for the basis pursuit model to
have a unique solution supported on . Indeed, it is also necessary, and
applies to a variety of other models. The paper also discusses ways to
recognize unique solutions and verify the uniqueness conditions numerically.Comment: 6 pages; revised version; submitte
Computer games: A double-edged sword?
Excessive computer game playing (ECGP) has already become a serious social problem. However, limited data from experimental lab studies are available about the negative consequences of ECGP on players' cognitive characteristics. In the present study, we compared three groups of participants (current ECGP participants, previous ECGP participants, and control participants) on a Multiple Object Tracking (MOT) task. The previous ECGP participants performed significantly better than the control participants, which suggested a facilitation effect of computer games on visuospatial abilities. Moreover, the current ECGP participants performed significantly worse than the previous ECGP participants. This more important finding indicates that ECGP may be related to cognitive deficits. Implications of this study are discussed. © 2008 Mary Ann Liebert, Inc.published_or_final_versio
A procedure for the change point problem in parametric models based on phi-divergence test-statistics
This paper studies the change point problem for a general parametric,
univariate or multivariate family of distributions. An information theoretic
procedure is developed which is based on general divergence measures for
testing the hypothesis of the existence of a change. For comparing the accuracy
of the new test-statistic a simulation study is performed for the special case
of a univariate discrete model. Finally, the procedure proposed in this paper
is illustrated through a classical change-point example
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