582 research outputs found
Cyclosporine pharmakokinetic profiles in liver, heart, and kidney transplant patients as determined HPLC
Cyclosporine metabolite concentrations in the blood of liver, heart, kidney, and bone marrow transplant patients.
Blocking of the B7-CD28 pathway increases the capacity of FasL<sup>+</sup> (CD95L<sup>+</sup>) dendritic cells to kill alloactivated T cells
Extending Construal Level Theory to Distributed Teams: Perception and Evaluation of Distant Others
Building on prior research on distributed teams that has identified physical and temporal distance as impediments to collaboration and relationship development, this paper explores how and why we treat geographically distant others differently from those who are proximal. According to construal level theory, physically- or temporally-distant events or objects are more psychologically distant and are more likely to be described in terms of their more general characteristics, while views of more proximal events or objects will be more detailed and nuanced. We extend construal level theory to the distributed team context by advancing propositions about how group members perceive and evaluate distant others in contrast to proximal others. By comparing to alternative computer-mediated communication and social psychological theories that have been applied to this phenomenon, we show that construal level theory offers parsimonious explanations as well as novel predictions about how and why we perceive and evaluate distant others differently. The paper then considers theoretical, methodological, and practical implications of construal level theory for distributed teams and other virtual settings
MSSM Baryogenesis and Electric Dipole Moments: An Update on the Phenomenology
We explore the implications of electroweak baryogenesis for future searches
for permanent electric dipole moments in the context of the minimal
supersymmetric extension of the Standard Model (MSSM). From a cosmological
standpoint, we point out that regions of parameter space that over-produce
relic lightest supersymmetric particles can be salvaged only by assuming a
dilution of the particle relic density that makes it compatible with the dark
matter density: this dilution must occur after dark matter freeze-out, which
ordinarily takes place after electroweak baryogenesis, implying the same degree
of dilution for the generated baryon number density as well. We expand on
previous studies on the viable MSSM regions for baryogenesis, exploring for the
first time an orthogonal slice of the relevant parameter space, namely the
(tan\beta, m_A) plane, and the case of non-universal relative gaugino-higgsino
CP violating phases. The main result of our study is that in all cases lower
limits on the size of the electric dipole moments exist, and are typically on
the same order, or above, the expected sensitivity of the next generation of
experimental searches, implying that MSSM electroweak baryogenesis will be soon
conclusively tested.Comment: 23 pages, 10 figures, matches version published in JHE
A model for predicting the evolution of multiple cracks on multiple length scales in viscoelastic composites
High-Risk Cervical Human Papillomavirus Infections among Human Immunodeficiency Virus-Positive Women in the Bahamas
Background\ud
\ud
High-risk (HR) HPV genotypes other than 16 and 18 have been detected in a significant proportion of immunocompromised females. We aim to evaluate the frequency of HR HPV genotypes in a population of HIV-positive Caribbean women.\ud
Methods\ud
\ud
One hundred sixty-seven consecutive, non-pregnant, HIV-positive females ≥18 years were recruited in this study. Each participant received a vaginal examination, PAP smear, and completed a questionnaire. DNA was extracted for HPV testing in 86 patients.\ud
Results\ud
\ud
Mean age was 39.1 years for women positive for HR HPV and 43.1 years for women negative for HR HPV (P value = 0.040). 78% (130/167) of the women had HR HPV infections; the prevalence of abnormal cervical cytology was 38% among women who were HR HPV-positive compared to women who were HR HPV-negative (22%). Fifty-one percent of the 86 women with available genotype carried infections with HPV 16 and/or HPV 18; genotypes of unknown risk were also frequently observed. Women who had a CD4+ count of ≤200 had 7 times increased odds of carrying HR HPV infection in comparison to women with CD4+>200.\ud
Conclusions\ud
\ud
HR HPV infections in HIV infected females may consist of more than just HPV 16 and 18, but also HPV 52 and 58. Further studies are needed to determine whether HPV 52 and 58 play a significant role in the development of cervical cytological abnormalities in HIV+ women
Efeitos da azatioprina sobre a depuração mucociliar após secção e anastomose brônquica em um modelo experimental em ratos
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