113,316 research outputs found
Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013
Abstract Background Despite its Gallic name, the French Bulldog is a breed of both British and French origin that was first recognised by The Kennel Club in 1906. The French Bulldog has demonstrated recent rapid rises in Kennel Club registrations and is now (2017) the second most commonly registered pedigree breed in the UK. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory, neurological and dermatological problems. The VetCompass™ Programme collates de-identified clinical data from primary-care veterinary practices in the UK for epidemiological research. Using VetCompass™ clinical data, this study aimed to characterise the demography and common disorders of the general population of French Bulldogs under veterinary care in the UK. Results French Bulldogs comprised 2228 (0.49%) of 445,557 study dogs under veterinary care during 2013. Annual proportional birth rates showed that the proportional ownership of French Bulldog puppies rose steeply from 0.02% of the annual birth cohort attending VetCompass™ practices in 2003 to 1.46% in 2013. The median age of the French Bulldogs overall was 1.3 years (IQR 0.6–2.5, range 0.0–13.0). The most common colours of French Bulldogs were brindle (solid or main) (32.36%) and fawn (solid or main) (29.9%). Of the 2228 French Bulldogs under veterinary care during 2013, 1612 (72.4%) had at least one disorder recorded. The most prevalent fine-level precision disorders recorded were otitis externa (14.0%, 95% CI: 12.6–15.5), diarrhoea (7.5%, 95% CI: 6.4–8.7), conjunctivitis (3.2%, 95% CI: 2.5–4.0), nails overlong (3.1%, 95% CI% 2.4–3.9) and skin fold dermatitis (3.0%, 95% CI% 2.3–3.8). The most prevalent disorder groups were cutaneous (17.9%, 95% CI: 16.3–19.6), enteropathy (16.7%, 95% CI: 15.2–18.3), aural (16.3%, 95% CI: 14.8–17.9), upper respiratory tract (12.7%, 95% CI: 11.3–14.1) and ophthalmological (10.5%, 95% CI: 9.3–11.9). Conclusions Ownership of French Bulldogs in the UK is rising steeply. This means that the disorder profiles reported in this study reflect a current young UK population and are likely to shift as this cohort ages. Otitis externa, diarrhoea and conjunctivitis were the most common disorders in French Bulldogs. Identification of health priorities based on VetCompass™ data can support evidence–based reforms to improve health and welfare within the breed
Promoting prosperity and stability: the EMU anchor in candidate and potential candidate countries
This paper analyses the euro as external anchor in the Western Balkans and their process of fiscal consolidation in the context of future EU accession.Promoting wealth and stability: the EMU anchor in candidate and potential candidate countries, Euro as external anchor in the Western Balkans, use of the euro in the Western Balkans, fiscal consolidation in candidate countries, use of the DM and later the euro, use of external anchors and parallel currencies, candidate countries fiscal surveillance procedures, candidate countries fiscal policies, economic affairs of candidate countries and Western Balkans, economic policy related to enlargement
Improving the energy efficiency of autonomous underwater vehicles by learning to model disturbances
Energy efficiency is one of the main challenges for long-term autonomy of AUVs (Autonomous Underwater Vehicles). We propose a novel approach for improving the energy efficiency of AUV controllers based on the ability to learn which external disturbances can safely be ignored. The proposed learning approach uses adaptive oscillators that are able to learn online the frequency, amplitude and phase of zero-mean periodic external disturbances. Such disturbances occur naturally in open water due to waves, currents, and gravity, but also can be caused by the dynamics and hydrodynamics of the AUV itself. We formulate the theoretical basis of the approach, and demonstrate its abilities on a number of input signals. Further experimental evaluation is conducted using a dynamic model of the Girona 500 AUV in simulation on two important underwater scenarios: hovering and trajectory tracking. The proposed approach shows significant energy-saving capabilities while at the same time maintaining high controller gains. The approach is generic and applicable not only for AUV control, but also for other type of control where periodic disturbances exist and could be accounted for by the controller. © 2013 IEEE
The agency of hybrids: overcoming the symmetrophobic block
We respond to ‘challenge 3’ presented in Rose, Jones and Truex’s excellent polemic by way of elucidating the meanings of hybrids, actants, agency and symmetry in Actor-Network Theory. We provide a (very brief) account of Latour’s project to unravel the modernist epistemological settlement that separates humans and non-humans in the world, and that alas so often results in errors and confusions. We contend that the framing of the challenge itself implies the very distinctions that ANT seeks to reject (namely the dichotomization of the world into mutually exclusive ‘subject’ and ‘object’ divisions). Following Latour, we argue that such pure forms do not exist—and furthermore that ‘agency’ is the property of complex hybrids comprised of various strands of human and non-human materials and abstract elements. This is the true meaning of the principle of symmetry! We conclude with some counter-challenges of our own
The Efficacy of Selected Desensitizing OTC Products: A Systematic Review.
Licensed by the Creative Commons Attribution LicenseObjectives. The aim of the present study was to review the published literature in order to identify relevant studies for inclusion and to determine whether there was any evidence on the clinical effectiveness of selected desensitizing toothpastes, calcium sodium phosphosilicate (CSPS), amorphous calcium phosphate (ACP), nanohydroxyapatite, and casein phosphopeptide-amorphous calcium phosphate (tooth mousse) on reducing dentine hypersensitivity (DH). Materials and Methods. Following a review of 593 papers identified from searching both electronic databases (PUBMED) and hand searching of relevant written journals, only 5 papers were accepted for inclusion. Results. Analysis of the included studies (3 CSPS and 2 ACP) would suggest that there may be some benefit for patients using these products for reducing DH. No direct comparative studies were available to assess all these products under the same conditions neither were there any comparative randomised controlled studies that compared at least two of these products in determining their effectiveness in treating DH. Conclusions. Due to the small number of included studies, there are limited clinical data to support any claims of clinical efficacy of these OTC products. Further studies are therefore required to determine the efficacy of these products in well-controlled RCT studies with a larger sample size
Magnetomechanical performance of directionally solidified Fe-Ga alloys
Iron-gallium alloys can produce magnetostrictions of ~400 ppm and might serve as mechanically robust actuator/sensing materials. However, for polycrystalline Fe-Ga alloys, the magnetostrictive performance decreases with the increasing deviations from the ideal <100> texture. In this paper, three directionally solidified Fe-Ga alloys with gallium contents of 17, 18.4, and 19.5 at. % were characterized at ambient temperature. These specimens exhibit high d33 and magnetic permeability when subjected to applied magnetic fields, indicating their suitability for light weight actuator applications but not for high force applications due to their low saturation magnetostriction and hence low blocking force. All the alloys produce significant changes in magnetization, around 0.7Ms-0.8Ms when subjected to cyclic compressive stresses of 51 MPa, making them promising candidate materials for sensing and energy harvesting applications. However, eddy current effects may easily become a problem when such materials are subjected to a high frequency vibration or magnetic field due to their intrinsic high magnetic permeability
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