Viral pathogenesis of SARS-CoV-2 infection and male reproductive health

Coronavirus disease 2019 (COVID-19) has emerged as a new public health crisis, threatening almost all aspects of human life. Originating in bats, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted to humans through unknown intermediate hosts, where it is primarily known to cause pneumonia-like complications in the respiratory system. Organ-to-organ transmission has not been ruled out, thereby raising the possibility of the impact of SARS-CoV-2 infection on multiple organ systems. The male reproductive system has been hypothesized to be a potential target of SARS-CoV-2 infection, which is supported by some preliminary evidence. This may pose a global threat to male fertility potential, as men are more prone to SARS-CoV-2 infection than women, especially those of reproductive age. Preliminary reports have also indicated the possibility of sexual transmission of SARS-CoV-2. It may cause severe complications in infected couples. This review focuses on the pathophysiology of potential SARS-CoV-2 infection in the reproductive organs of males along with their invasion mechanisms. The risks of COVID-19 on male fertility as well as the differences in vulnerability to SARS-CoV-2 infection compared with females have also been highlighted.Peer reviewe

Emotion Ideology Mediates Effects of Risk Factors on Alexithymia Development

Despite its connection to mental and behavioral health complications, elevated alexithymia tends to be associated with low responsiveness and high resistance to psychological intervention. To further understanding of potential treatment targets for clients with alexithymic traits, the present study explored the (a) independent contributions of various risk factors to statistical predictions of alexithymic trait severity, (b) generalizability of risk factor contributions across two culturally distinct samples, and (c) potential for emotion ideology (i.e., beliefs about emotion and emotional experience) to mediate such contributions. Preliminary results suggest emotion socialization and child abuse may be salient contributors to alexithymia severity, whereas effects of trauma exposure may be limited to samples with high overall exposure to alexithymia risk-factors. Moreover, emotion ideology mediates the relation between risk-factor exposure and alexithymia severity. Thus, psychotherapeutic interventions targeting emotion ideology may be beneficial when working with clients with elevated alexithymia