Analytic Torsion on Hyperbolic Manifolds and the Semiclassical Approximation for Chern-Simons Theory

The invariant integration method for Chern-Simons theory for gauge group SU(2) and manifold \Gamma\H^3 is verified in the semiclassical approximation. The semiclassical limit for the partition function associated with a connected sum of hyperbolic 3-manifolds is presented. We discuss briefly L^2 - analytical and topological torsions of a manifold with boundary.Comment: 12 pages, LaTeX fil

Personalismo e política: Atualidade de um homem, pertinência de uma ideia

O presente artigo discute a perspectiva de “atualidade” no pensamento do filósofo francêsEmmanuel Mounier. O que se pretende é saber em que medida as reflexões deste filósofo,morto há mais de 60 anos, podem contribuir para compreendermos e confrontarmos com acrise atual. Como fundador da revista Esprit e do movimento personalista iniciado depois dacrise de 1929 na Europa, Mounier se engaja na liderança que inspira a formação de umpersonalismo comunitário de viés fortemente atuante na dimensão política e social. Veremoscomo a flexibilidade de seu pensamento e a pertinência de suas ideias nos ajudam a refletirsobre o momento atual em que vivemos

Interview with Diane Brentari

Diane Brentari is co-director of the Center for Gesture, Sign and Language at the University of Chicago. She has published several books, such as Sign Language Phonology (Cambridge University Press, 2019) and Shaping Phonology (2018). Her research focuses on the role of modality in language, sign language phonology, how sign languages develop through historical time, and sign language typology.---------------------------------------------------------------------------------ENTREVISTA COM DIANE BRENTARIDiane Brentari é professora de linguística Mary K. Werkman e codiretora do Center for Gesture, Sign and Language da Universidade de Chicago. Publicou vários livros, como Sign Language Phonology (Cambridge University Press, 2019) e Shaping Phonology (2018). Sua pesquisa enfoca o papel da modalidade na linguagem, a fonologia da língua de sinais, como as línguas de sinais se desenvolvem ao longo do tempo histórico e a tipologia da língua de sinais.---Original em inglês.Diane Brentari is the Mary K. Werkman Professor of Linguistics and Co-Director of the Center for Gesture, Sign and Language at the University of Chicago. She has published several books, such as Sign Language Phonology (Cambridge University Press, 2019) and Shaping Phonology (2018). Her research focuses on the role of modality in language, sign language phonology, how sign languages develop through historical time, and sign language typology.---Original in English

O MUSEU DE GEOCIÊNCIAS DA UFPA

O objetivo deste trabalho consiste em uma abordagem sobre o Museu de Geociências da Universidade Federal do Pará (GEOMU/UFPA). Por se tratar de um museu vinculado à referida universidade, o tratamento do mesmo se amplia na tipologia de ‘museu universitário’, termo este que será apresentado no estudo. Ademais, como GEOMU faz parte da categoria de ‘museu de ciência e da técnica’ este conceito também será a presentada. Os dados da pesquisa foram baseados não só em pesquisas bibliográficas como também na pesquisa in loco e entrevista realizada com um dos técnicos responsáveis pelo referido museu

Candidemia Surveillance in Brazil: Evidence for a Geographical Boundary Defining an Area Exhibiting an Abatement of Infections by Candida albicans Group 2 Strains

Prospective population surveillance has been conducted for candidemia in Brazil (A. L. Colombo, M. Nucci, B. J. Park, et al., J. Clin. Microbiol. 44:2816-2823, 2006). in the present study, a total of 63 isolates from 61 patients, representing 11 medical centers from nine geographic regions, were characterized by multilocus sequence typing (MLST). A total of 48 unique profiles or diploid sequence types (DSTs) were observed, with nine new sequence types (STs) and 32 new DSTs. There were no apparent correlations between center/region and DST patterns. Subtypes were compared to those in a known characterized reference set, including a large database of strains obtained worldwide. Significantly, only one C. albicans group 2 isolate was found in our collection, although isolates from this particular group are commonly found worldwide. These data, combined with information from other previously reported studies, establish a statistically significant diminishment of group 2 strains in Central and South America, including Mexico and portions of the Southwestern United States.Centers for Disease Control and Prevention (CDC)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Ctr Dis Control & Prevent, Mycot Dis Branch, Atlanta, GA 30333 USAUniversidade Federal de São Paulo, Div Infect Dis, São Paulo, BrazilUniversidade Federal de São Paulo, Div Infect Dis, São Paulo, BrazilWeb of Scienc

Metodologia para desenvolvimento de subsistemas de TT&C em CubeSats

The CubeSats concept began in 1999 as a collaboration between California Polytechnic State University and Stanford University, and today it is an accessible and widely used by educational institutions and the private sector for the development of small satellites. As these small satellites are unmanned, the Telemetry Tracking and Remote Control (TT&C) system is one of the most critical to the mission, as their failure results in its premature end. This work presents a study of the main concepts related to the TT&C system, especially with regard to minimum power and transmission speed to ensure correct and complete transmission of payload data. Posteriorly, using the concepts presented, a set of needs is elaborated for its good functioning and good integration with the other systems of a CubeSat

Pesquisas sobre línguas de sinais: uma contribuição à luz dos 25 anos de “Por uma gramática de línguas de sinais”

Introduction to Revista Linguíʃtica vol. 16, no. 3.Apresentação à Revista Linguíʃtica v.16, n.3

Qualitative analysis of the behavior of the seedlings of sugarcane of different varieties using the method of temporary immersion

Sugar cane is a culture of great importance worldwide due to the fact it is the raw material needed for the production of sugar, ethanol, and biomass, among other products. The micro-propagation of seedlings in a lab generates superior production when compared to the conventional process of propagation in the field. Therefore, it is seen as an alternative to produce healthy seedlings that present the same genetic load of the matrices. A disadvantage of micro-propagation is the high cost of workforce used in the process. The System of Temporary Immersion (SIT) was createdwith the goal of solving this issue. At the bio-factory Governador Miguel Arraes of the Center of Strategic Technology of the Northeast (CETENE), this system consists of 2 PET bottles of 5L (Bioreactors – BITs), a group of hoses and two Millipore filters of 0.22µm as well as automated controllers. Within the BITs it is possible to multiply a higher quantity of plants decreasing, this way, the time within the lab. Theobjective of this study is the qualitative analysis of the behavior of the System of Temporary Immersion using seedlings of different varieties of sugar cane. The methodology consisted of transferring the content of 1 or 3 pots, depending on the test, to the bioreactor with 200ml and 500ml of culture mean respectively. The varieties used were RB 86 3129 and B 8008 because there are fewer studies about them and of great interest to the Bio-factory. The variety RB 86 3129, on the first pricking, presented a better response than the B 8008, and days later the majority presented loss through contamination

Characterization of serous retinal detachments in uveitis patients with optical coherence tomography

To determine the prevalence of serous retinal detachments (SRD) using optical coherence tomography (OCT) in a large database of patients with uveitis from a tertiary referral setting, to describe clinical features of patients with SRD, and to ascertain retinal architectural features found in association with SRD. Main outcome measures Prevalence of SRD in uveitis patients imaged with OCT, correlation of visual acuity with SRD, anatomic subtypes of uveitis identified, and association of SRD with various subtypes of macular edema (focal and diffuse) and retinal architectural abnormalities. Design Retrospective, single-setting cross-sectional study of all OCTs in a digital imaging base ordered on patients from a tertiary referral uveitis clinic between July 2006 and March 2008. Results SRD were identified in 17 of 111 uveitis patients (15 %) reviewed; bilateral SRD were found in 5 of 17 patients (29 %). Intermediate uveitis was the most common disease association (47 %), but other conditions identified included Vogt-Koyanagi-Harada syndrome, multifocal choroiditis/panuveitis, and sarcoidosis. Retinal architectural features identified in association with SRD included focal macular edema (59 %), diffuse macular edema (50 %), any intraretinal edema (77 %), both diffuse and focal macular edema (32 %), and retinal pigment epithelial alteration (27 %). Moderate or severe visual impairment, defined as visual acuity 20/50 or poorer was seen in 71 % of patients with SRD. Poorer visual acuity was correlated with increased central subfield thickness in patients with SRD (r2=0.41, p<0.001). Conclusion SRD were present in 15 % of the uveitis patients reviewed. Moderate to severe vision impairment was present in the majority of eyes (71 %) with SRD. Diffuse macular edema and focal cystoid macular edema were the OCT features most commonly associated with SRD. Intermediate and panuveitis were the most common anatomic sites of inflammation. A variety of pathogenic mechanisms, both inflammatory and non-inflammatory, may be involved in SRD in uveitis patients; identification of the precise mechanism is important for appropriate therapy.This work is supported in part by an Unrestricted Grant from Research to Prevent Blindness (Casey Eye Institute, Emory Eye Center), the Stan and Madelle Rosenfeld Family Trust (JTR), the William and Mary Bauman Foundation (JTR), the William C. Kuzell Foundation (JTR), and the Ronald G. Michels Fellowship Foundation (SY)

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

Introduction Alzheimer's disease is a neurodegenerative disorder that is hypothesized to involve epigenetic dysregulation of gene expression in the brain. Methods We performed an epigenome-wide association study to identify differential DNA methylation associated with neuropathology in prefrontal cortex and superior temporal gyrus samples from 147 individuals, replicating our findings in two independent data sets (N = 117 and 740). Results We identify elevated DNA methylation associated with neuropathology across a 48-kb region spanning 208 CpG sites within the HOXA gene cluster. A meta-analysis of the top-ranked probe within the HOXA3 gene (cg22962123) highlighted significant hypermethylation across all three cohorts (P = 3.11 × 10−18). Discussion We present robust evidence for elevated DNA methylation associated with Alzheimer's disease neuropathology spanning the HOXA gene cluster on chromosome 7. These data add to the growing evidence highlighting a role for epigenetic variation in Alzheimer's disease, implicating the HOX gene family as a target for future investigation