The death of the architect: the need for integral design teams in the generation of concepts for a sustainable built environment

No abstract

The effect of alteration of intracellular 2,3-DPG concentration upon oxygen binding of intact erythrocytes containing normal and mutant hemoglobins

The oxygen dissociation and association characteristics of intact erythrocytes containing normal and mutant hemoglobins and variable concentrations of 2,3-DPG (0 to 25 mM) have been studied by a continuous-recording polarographic technique. The oxygen affinity of cells containing Hb AC and CC is normal, Hb SS is considerably lower while that of Hb AS and SC is intermediate. Cord blood and cells with Hb Köln have an increased affinity for oxygen. Plots of P 50 against 2,3-DPG concentrations produce asymptotic curves in all cells studied. The effect of changes of 2,3-DPG upon oxygen binding in the types of cells studied expressed as δP 50 δ 2,3 - DPG decreases in the following order: SS>AS and SC>AA, AC and CC > F and Köln. The molecular basis for the increased response to 2,3-DPG by cells containing Hb S as compared to the normal response of hemoglobin S in solution is briefly discussed

Integral design Workshop for ZEB

Very few designers have the necessary skills or experience to design 0 impact buildings and environments. As complexity of the design increases with the efforts to reach the limit of zero impact, it really becomes necessary to involve all building design disciplines in the earlier stage of the NZEB design project. This is not something done by merely putting the different designers together around one table, but needs more support. Experiences with tools to help with and to support the group design process will be presented. In the last years different design workshops have been held for Zero energy building design, in which more than 100 experienced professionals, architects of BNA and consulting engineers of NL Ingenieurs participated. The steps for further improvement will be presented to stimulate the creation of new concepts to achieve 0 impact buildings and environments

Integral design method for supporting conceptual building design

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Leren Integraal te ontwerpen

In 2000 is TVVL, in samenwerking met BNA en de TU Delft, gestart met het project ‘Integraal ontwerpen’. Er is gekeken naar de meerwaarde van het toepassen van methodisch ontwerpen bij het conceptuele ontwerpproces in de gebouwde omgeving. Het betreft een ontwerpmethode van Van den Kroonenberg [1]. Er volgde een ontwerpwedstrijd ‘Integraal ontwerpen’ aan de TU Delft en TU/e [2], in het kader van de multidisciplinaire/integrale benadering van het onderwijs. Dit heeft in 2005 een vervolg gekregen in het onderwijs aan de TU Eindhoven [3,4]. Met name het ontwikkelde concept van multidisciplinaire, conceptuele ontwerpworkshops werd overgenomen [5]