50 research outputs found
S1760 Interleukin-6 Mediates the Extra-Intestinal Thrombosis Associated With Experimental Colitis in Mice
Radiation-induced microvascular dysfunction in rat mesentery: Role of leukocyte-endothelial cell adhesion
Bile duct ligation and fasting reduce microcirculatory disturbances in indomethacin-induced intestinal inflammation in the rat
Measurement of Phosphatidylcholine Hydroperoxide in Mild Ischemia-Reperfusion Injury in Rat Intestine.
Monoclonal Antibodies to Human Tumor Necrosis Factors Alpha and Beta: Application for Affinity Purification, Immunoassays, and as Structural Probes
Application of methionine as a detector molecule for the assessment of oxygen radical generation by human neutrophils and endothelial cells.
Diverse cell types can generate reactive oxygen species (ROS) which are implicated in many disease processes and are ascribed both beneficial and deleterious roles. In vitro studies of this phenomenon indicate that properties of the microenvironment in culture influence the cells' behaviour with regard to ROS generation in vivo. To date, however, the assessment of cellular ROS generation has been limited to techniques which are invasive of the culture environment, or require cells to be in suspension. This study describes the application of NMR spectroscopy to the detection of ROS generation, a technique which is non-invasive of the cell culturing environment