164 research outputs found
Assessing the Role and Capacity of Water Management Organizations for Ensuring Delta Food Security in Bangladesh
The coastal zone, consisting of one-third country\u27s area, is the most climate-vulnerable region of Bangladesh. The country has invested significantly in coastal zone through the construction and rehabilitation of polders. Despite vast opportunities, land productivity in the polders is very low due to poor water governance and management. To improve in-polder water management, the responsibility of operation and maintenance of the polder water infrastructure has been transferred to Water Management Organizations (WMOs) since 2001. WMOs are currently voluntary organizations but are very important for micro-level agricultural water management. A study was conducted in 2017 and 2018 in a medium saline polder; with a major focus on organizational behaviour: hierarchy in decision-making, transparency, financial accountability, leadership, internal communication, and motivational incentives of the WMOs. The data were collected through a structured questionnaire from 192 respondents of randomly selected eight Water Management Groups (WMGs – the lowest tier of WMOs), out of 40 WMGs of the polder. The results revealed that the WMGs operations are not fully participatory in principle yet. Even the transparency, financial accountability, leadership, and internal communications within WMGs are not strong enough to take the organizational responsibility to address future challenges in food security of the climate-vulnerable polder communities. Improving drainage through efficient water management showed a yield gain of at least 1.5 t/ha in the wet season only. In addition, improved drainage fosters sustainable year-round cropping with high-yielding, high-value and nutrition-rich crops with 2 to 3 times higher productivity than the traditional cropping system. Therefore, investment in water governance particularly in improving drainage in the polders could be a major game-changer in sustaining the food security of the climate-vulnerable polder communities of Bangladesh. The study identified the knowledge gap as a significant concern that demands the need for capacity building of the WMOs
Histochemical techniques in plant science: more than meets the eye
Histochemistry is an essential analytical tool interfacing extensively with plant science. The literature is indeed constellated with examples showing its use to decipher specific physiological and developmental processes, as well as to study plant cell structures. Plant cell structures are translucent unless they are stained. Histochemistry allows the identification and localization, at the cellular level, of biomolecules and organelles in different types of cells and tissues, based on the use of specific staining reactions and imaging. Histochemical techniques are also widely used for the in vivo localization of promoters in specific tissues, as well as to identify specific cell wall components such as lignin and polysaccharides. Histochemistry also enables the study of plant reactions to environmental constraints, e.g. the production of reactive oxygen species (ROS) can be traced by applying histochemical staining techniques. The possibility of detecting ROS and localizing them at the cellular level is vital in establishing the mechanisms involved in the sensitivity and tolerance to different stress conditions in plants. This review comprehensively highlights the additional value of histochemistry as a complementary technique to high-throughput approaches for the study of the plant response to environmental constraints. Moreover, here we have provided an extensive survey of the available plant histochemical staining methods used for the localization of metals, minerals, secondary metabolites, cell wall components, and the detection of ROS production in plant cells. The use of recent technological advances like CRISPR/Cas9-based genome-editing for histological application is also addressed. This review also surveys the available literature data on histochemical techniques used to study the response of plants to abiotic stresses and to identify the effects at the tissue and cell levels.The authors would like to thank Head of the Department, University of Allahabad, Allahabad, India, for providing the necessary facilities to carry out the work
Quality Infrastructure of National Metrology Institutes: A Comparative Study
Each country has its own system of Quality Infrastructure (QI) developed for the effective operations, management, regulations, control of national trade, international exchanges of goods & collaborations and recognition of their products and services to enable them to enter into the global market. These QI systems consist of national governments, civic, public and private institutions, organizations, boards, associations, forums, scientific societies, federations industries etc. These agencies work in coordination and with synergy to formulate, suggest, execute, disseminate and implement, as per their relevant responsibilities; the national policies, procedures; guidelines, legal & regulatory structure, and good practices to support and strengthen the quality for safe & environmentally friendly products, services, and processes. It relies on metrology, standardization, accreditation, and conformity assessment. Several countries have strong QI, and accordingly, have proper industrial and economic growth. On the contrary, some of the countries lack the necessary infrastructure to meet the quality standards, and as a result, they face problems and challenges in this competitive world. This paper describes the essential components of stronger International Quality Infrastructure (IQI) and the National Quality Infrastructure (NQI). A comparative study carried out on the NQIs of 9 leading countries is also discussed. A comparative study on the Global Quality Infrastructure Index (GQII) of the top 10 economies is also included. Admittedly, though utmost care is taken to accommodate most relevant information, some of the unnoticed discrepancies are not ruled out, which may be unintentional. It is hoped that this paper would be useful for students, researchers, academicians, scientists, metrologists, quality experts, administrators, and policymakers as an information bank on NQIs and GQIIs of several countries
Bacterial diversity associated with urinary tract infections in humans
The present study aimed to evaluate the concepts of epidemiology, uropathogenic,
diagnosis, prevention, and treatment of urinary tract infections (UTI) in humans. One of the
most frequent infections that affect people is UTIs. During childhood they are equally
common in boys and girls, and after that, they are more common in girls. In both of the
general population and hospital environment, women frequently experienced at least one UTI
in their lifetime. The existence of bacteriuria and pyuria are the 2 most significant signs of
UTIs. Frequent urination, pain during urination, and soreness in the side or lower back are
among the main symptoms of UTI. These infections are classified into 3 primary types:
asymptomatic bacteriuria, lower UTI (cystitis), and febrile upper UTI (acute pyelonephritis),
because such classification supports understanding of the infection‟s etiology. UTI can be
diagnosed through a combination of positive urine tests and/or culture and symptoms. Dipstick
urinalysis is widely used due to its ease of availability and utility; however, the outcomes must
be evaluated by considering the patient‟s pretest probability depending on the characteristics
and symptoms. Most UTIs can be treated with antibiotics such as Amoxicillin, cephalexin, and
doxycycline. But the Gram-positive bacterium (Enterobacter faecalis) exhibited great
resistance to erythromycin, while the Gram-negative bacterium (Escherichia coli) displayed
great resistance to ampicillin. So, there is an urgent need for a combination between organic
treatments and antibiotics to treat the complicated UTI. For example, the plant-based
treatments, such as cranberry juice, are efficient in treating the UTI and can be used as an
alternative to combating the bacteria that cause UTI
Lyra's Cosmology of Massive String in Anisotropic Bianchi-II Space-time
The paper deals with a spatially homogeneous and totally anisotropic Bianchi
II cosmological models representing massive strings in normal gauge for Lyra's
manifold. The modified Einstein's field equations have been solved by applying
variation law for Hubble's parameter. This law generates two type of solutions
for average scale factor, one is of power law type and other is of exponential
law type. The power law describes the dynamics of Universe from big bang to
present epoch while exponential law seems reasonable to project dynamics of
future Universe. It has been found that the displacement actor is a
decreasing function of time and it approaches to small positive value at late
time, which is collaborated with Halford (1970) as well as recent observations
of SN Ia. The study reveals that massive strings dominate in early Universe and
eventually disappear from Universe for sufficiently large time, which is in
agreement with the current astronomical observations.Comment: 12 pages, 5 figure
BINGO: A code for the efficient computation of the scalar bi-spectrum
We present a new and accurate Fortran code, the BI-spectra and
Non-Gaussianity Operator (BINGO), for the efficient numerical computation of
the scalar bi-spectrum and the non-Gaussianity parameter f_{NL} in single field
inflationary models involving the canonical scalar field. The code can
calculate all the different contributions to the bi-spectrum and the parameter
f_{NL} for an arbitrary triangular configuration of the wavevectors. Focusing
firstly on the equilateral limit, we illustrate the accuracy of BINGO by
comparing the results from the code with the spectral dependence of the
bi-spectrum expected in power law inflation. Then, considering an arbitrary
triangular configuration, we contrast the numerical results with the analytical
expression available in the slow roll limit, for, say, the case of the
conventional quadratic potential. Considering a non-trivial scenario involving
deviations from slow roll, we compare the results from the code with the
analytical results that have recently been obtained in the case of the
Starobinsky model in the equilateral limit. As an immediate application, we
utilize BINGO to examine of the power of the non-Gaussianity parameter f_{NL}
to discriminate between various inflationary models that admit departures from
slow roll and lead to similar features in the scalar power spectrum. We close
with a summary and discussion on the implications of the results we obtain.Comment: v1: 5 pages, 5 figures; v2: 35 pages, 11 figures, title changed,
extensively revised; v3: 36 pages, 11 figures, to appear in JCAP. The BINGO
code is available online at
http://www.physics.iitm.ac.in/~sriram/bingo/bingo.htm
Accelerating Bianchi Type-V Cosmology with Perfect Fluid and Heat Flow in Saez-Ballester Theory
In this paper we discuss the law of variation of scale factor which yields a time-dependent deceleration
parameter (DP) representing a new class of models that generate a transition of
universe from the early decelerated phase to the recent accelerating phase.
Exact solutions of Einstein's modified field equations with perfect fluid and
heat conduction are obtained within the framework of Saez-Ballester
scalar-tensor theory of gravitation and the model is found to be in good
agreement with recent observations. We find, for n = 3, k = 1, the present
value of DP in derived model as q_0 = -0.67 which is very near to the observed
value of DP at present epoch. We find that the time-dependent DP is sensible
for the present day Universe and give an earmark description of evolution of
universe. Some physical and geometric properties of the models are also
discussed.Comment: 12 pages, 5 figure
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are updated routinely with additional data and refined analytical methods. GBD 2021 presents, for the first time, estimates of health loss due to the COVID-19 pandemic. Methods: The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. Data were extracted from vital registration systems, verbal autopsies, censuses, household surveys, disease-specific registries, health service contact data, and other sources. YLDs were calculated by multiplying cause-age-sex-location-year-specific prevalence of sequelae by their respective disability weights, for each disease and injury. YLLs were calculated by multiplying cause-age-sex-location-year-specific deaths by the standard life expectancy at the age that death occurred. DALYs were calculated by summing YLDs and YLLs. HALE estimates were produced using YLDs per capita and age-specific mortality rates by location, age, sex, year, and cause. 95% uncertainty intervals (UIs) were generated for all final estimates as the 2·5th and 97·5th percentiles values of 500 draws. Uncertainty was propagated at each step of the estimation process. Counts and age-standardised rates were calculated globally, for seven super-regions, 21 regions, 204 countries and territories (including 21 countries with subnational locations), and 811 subnational locations, from 1990 to 2021. Here we report data for 2010 to 2021 to highlight trends in disease burden over the past decade and through the first 2 years of the COVID-19 pandemic. Findings: Global DALYs increased from 2·63 billion (95% UI 2·44–2·85) in 2010 to 2·88 billion (2·64–3·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14·2% (95% UI 10·7–17·3) between 2010 and 2019. Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardised all-cause DALY rates since 2019 of 4·1% (1·8–6·3) in 2020 and 7·2% (4·7–10·0) in 2021. In 2021, COVID-19 was the leading cause of DALYs globally (212·0 million [198·0–234·5] DALYs), followed by ischaemic heart disease (188·3 million [176·7–198·3]), neonatal disorders (186·3 million [162·3–214·9]), and stroke (160·4 million [148·0–171·7]). However, notable health gains were seen among other leading communicable, maternal, neonatal, and nutritional (CMNN) diseases. Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). Non-communicable diseases contributed 1·73 billion (95% UI 1·54–1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5–9·5). Between 2010 and 2021, among the 25 leading Level 3 causes, age-standardised DALY rates increased most substantially for anxiety disorders (16·7% [14·0–19·8]), depressive disorders (16·4% [11·9–21·3]), and diabetes (14·0% [10·0–17·4]). Age-standardised DALY rates due to injuries decreased globally by 24·0% (20·7–27·2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61·3 years (58·6–63·6) in 2010 to 62·2 years (59·4–64·7) in 2021. However, despite this overall increase, HALE decreased by 2·2% (1·6–2·9) between 2019 and 2021. Interpretation: Putting the COVID-19 pandemic in the context of a mutually exclusive and collectively exhaustive list of causes of health loss is crucial to understanding its impact and ensuring that health funding and policy address needs at both local and global levels through cost-effective and evidence-based interventions. A global epidemiological transition remains underway. Our findings suggest that prioritising non-communicable disease prevention and treatment policies, as well as strengthening health systems, continues to be crucially important. The progress on reducing the burden of CMNN diseases must not stall; although global trends are improving, the burden of CMNN diseases remains unacceptably high. Evidence-based interventions will help save the lives of young children and mothers and improve the overall health and economic conditions of societies across the world. Governments and multilateral organisations should prioritise pandemic preparedness planning alongside efforts to reduce the burden of diseases and injuries that will strain resources in the coming decades. Funding: Bill & Melinda Gates Foundation
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