Comment on `Strong Vortex Liquid Correlation' from Multiterminal Measurements on Untwinned YBa2_2Cu3_3O7−δ_{7-\delta} Single Crystals'

A.Rydh and \"O.Rapp [Phys. Rev. Lett. {\bf 86}, 1873 (2001).] claim that the vortex liquid in untwinned YBa$_2$Cu$_3$O$_{7-\delta}$ crystals is correlated above the melting transition, in striking contrast to previous work [D.L\'opez {\it et al.}, Phys. Rev. Lett. {\bf 76}, 4034 (1996).]. In this Comment we present new measurements using the same experimental technique on twinned and untwinned YBa$_2$Cu$_3$O$_{7-\delta}$ crystals with similar overall characteristics as those reported by Rydh and Rapp . The comparison of the vortex correlation response in both cases indicates that the central conclusion of their work is not correct. Our results reconfirm the work by L\'opez {\it et al.} and points on the origin of the misinterpretation in the work of Rydh and Rapp.Comment: comment on A.Rydh and \"O.Rapp, Phys. Rev. Lett. {\bf 86}, 1873 (2001). accepted in Phys. Rev. Let

First-Order Vortex Lattice Melting and Magnetization of YBa2_2Cu3_3O$_{7-\delta}

We present the first non-mean-field calculation of the magnetization $M(T)$ of YBa$_2$Cu$_3$O$_{7-\delta}$ both above and below the flux-lattice melting temperature $T_m(H)$. The results are in good agreement with experiment as a function of transverse applied field $H$. The effects of fluctuations in both order parameter $\psi({\bf r})$ and magnetic induction $B$ are included in the Ginzburg-Landau free energy functional: $\psi({\bf r})$ fluctuates within the lowest Landau level in each layer, while $B$ fluctuates uniformly according to the appropriate Boltzmann factor. The second derivative $(\partial^2 M/\partial T^2)_H$ is predicted to be negative throughout the vortex liquid state and positive in the solid state. The discontinuities in entropy and magnetization at melting are calculated to be $\sim 0.034\, k_B$ per flux line per layer and $\sim 0.0014$~emu~cm$^{-3}$ at a field of 50 kOe.Comment: 11 pages, 4 PostScript figures in one uuencoded fil

First-Order Melting of a Moving Vortex Lattice: Effects of Disorder

We study the melting of a moving vortex lattice through numerical simulations with the current driven 3D XY model with disorder. We find that there is a first-order phase transition even for large disorder when the corresponding equilibrium transition is continuous. The low temperature phase is an anisotropic moving glass.Comment: Important changes from original version. Finite size analysis of results has been added. Figure 2 has been changed. There is a new additional Figure. To be published in Physical Review Letter

First order phase transition of the vortex lattice in twinned YBa2Cu3O7 single crystals in tilted magnetic fields

We present an exhaustive analysis of transport measurements performed in twinned YBa2Cu3O7 single crystals which stablishes that the vortex solid-liquid transition is first order when the magnetic field H is applied at an angle theta away from the direction of the twin planes. We show that the resistive transitions are hysteretic and the V-I curves are non-linear, displaying a characteristic s-shape at the melting line Hm(T), which scales as epsilon(theta)Hm(T,theta). These features are gradually lost when the critical point H*(theta) is approached. Above H*(theta) the V-I characteristics show a linear response in the experimentally accessible V-I window, and the transition becomes reversible. Finally we show that the first order phase transition takes place between a highly correlated vortex liquid in the field direction and a solid state of unknown symmetry. As a consequence, the available data support the scenario for a vortex-line melting rather than a vortex sublimation as recently suggested [T.Sasagawa et al. PRL 80, 4297 (1998)].Comment: 10 pages, 8 figures, submitted to PR

Energy cost associated with vortex crossing in superconductors

Starting from the Ginzburg-Landau free energy of a type II superconductor in a magnetic field we estimate the energy associated with two vortices crossing. The calculations are performed by assuming that we are in a part of the phase diagram where the lowest Landau level approximation is valid. We consider only two vortices but with two markedly different sets of boundary conditions: on a sphere and on a plane with quasi-periodic boundary conditions. We find that the answers are very similar suggesting that the energy is localised to the crossing point. The crossing energy is found to be field and temperature dependent -- with a value at the experimentally measured melting line of $U_\times \simeq 7.5 k T_m \simeq 1.16/c_L^2$, where $c_L$ is the Lindemann melting criterion parameter. The crossing energy is then used with an extension of the Marchetti, Nelson and Cates hydrodynamic theory to suggest an explanation of the recent transport experiments of Safar {{\em et al.}\ }.Comment: 15 pages, RevTex v3.0, followed by 5 postscript figure

Molecular pathogenesis of sporadic prion diseases in man

The yeast, fungal and mammalian prions determine heritable and infectious traits that are encoded in alternative conformations of proteins. They cause lethal sporadic, familial and infectious neurodegenerative conditions in man, including Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker syndrome (GSS), kuru, sporadic fatal insomnia (SFI) and likely variable protease-sensitive prionopathy (VPSPr). The most prevalent of human prion diseases is sporadic (s)CJD. Recent advances in amplification and detection of prions led to considerable optimism that early and possibly preclinical diagnosis and therapy might become a reality. Although several drugs have already been tested in small numbers of sCJD patients, there is no clear evidence of any agent’s efficacy. Therefore, it remains crucial to determine the full spectrum of sCJD prion strains and the conformational features in the pathogenic human prion protein governing replication of sCJD prions. Research in this direction is essential for the rational development of diagnostic as well as therapeutic strategies. Moreover, there is growing recognition that fundamental processes involved in human prion propagation – intercellular induction of protein misfolding and seeded aggregation of misfolded host proteins – are of far wider significance. This insight leads to new avenues of research in the ever-widening spectrum of age-related human neurodegenerative diseases that are caused by protein misfolding and that pose a major challenge for healthcare

Density-functional theory of freezing of vortex-liquid in quasi two-dimensional superconductors

We present a theory of vortex liquid-to-solid transition in homogeneous quasi 2D superconductors. The free energy is written as a functional l of density of zeroes of the fluctuating order parameter. The transition is weakly first-order and well below the Hc2(T) line. Transition temperature, discontinuities of the average Abrikosov ratio and of the average superfluid density, the Debay-Waller factor and the latent heat are in good agreement with Monte Carlo simulations. The density is only weakly modulated in the "vortex-solid" phase, consistent with the density-wave behavior.Comment: 12 pages and 1 figure available upon request, LaTex Version 2.09, submitted to Phys. Rev. Let

The Phase Diagram of Disordered Vortices from London Langevin Simulations

We study the phase diagram of vortex matter in disordered type-II superconductors. We performed numerical simulations in the London Langevin approximation, using a new realistic representation of the disorder. At low magnetic fields we find a disentangled and dislocation free Bragg-glass regime. Increasing the field introduces disorder-driven entanglement in a discontinuous manner, leading to a vortex-glass phase, which subsequently melts into the vortex liquid. The obtained phase boundaries are in quantitative agreement with the experimental data.Comment: 4 pages, revtex, 8 postscript figures include

Electrocardiographic changes in patients undergoing targeted temperature management

ObjectivesTargeted temperature management is the recommended therapy for comatose patients after an out‐of‐hospital cardiac arrest resuscitation due to the reduction in neurological damage and improved outcomes. However, there may result in electrocardiographic instability depending on the degree of targeted temperature management, including minor or life‐threatening dysrhythmias or conduction delays. This project aims to describe the frequency of ECG interval changes and clinically relevant dysrhythmias in targeted temperature management patients.MethodsThis is a retrospective observational study from January 2009 to December 2015. Patients who qualified for the study had a non‐traumatic cardiac arrest with a return of spontaneous circulation, received targeted temperature management at 33.5°C for 24 hours followed by 16 hours of rewarming. ECG interval changes and dysrhythmias were recorded immediately after return of spontaneous circulation, and at 24 and 48 hours post return of spontaneous circulation.ResultsA total of 322 patients (age 61.0 ± 16.9 years) had targeted temperature management initiated during the study period, of which 169 had complete data and 13 died prior to completing 24 hours of hypothermia. There were statistically significant changes during targeted temperature management in heart rate (96.7 ± 26.0/min before targeted temperature management; 69.5 ± 19.1/min during, P < 0.001), QRS duration (115.1 ± 32.6 ms before targeted temperature management; 107.8 ± 27.9 ms during targeted temperature management, P < 0.001), and QTc (486.3 ± 52.8 ms before targeted temperature management; 526.9 ± 61.7 ms during targeted temperature management, P < 0.001). There were cardiac dysrhythmias that received treatment during cooling and rewarming.ConclusionDuring the period of targeted temperature management and rewarming, we observed few self‐limiting ECG interval changes and no clinically significant dysrhythmias in this population during the period of targeted temperature management.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/156464/2/emp212104_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156464/1/emp212104.pd