2,080 research outputs found

    Intelligent Based Terrain Preview Controller for a 3-axle Vehicle

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    Presented at 13th International Symposium on Advanced Vehicle Control, AVEC'16; Munich 13-16/09/2016The paper presents a six-wheel half longitudinal model and the design of a dual level control architecture. The first (top) level is designed using a Sugeno fuzzy inference feedforward architecture with and without preview. The second level of controllers are locally managing each wheel for each axle. As the vehicle is moving forward the front wheels and suspension units will have less time to respond when compared to the middle and rear units, hence a preview sensor is used to compensate. The paper shows that the local active suspensions together with the Sugeno Fuzzy, (locally optimised using subtractive clustering), Feedforward control strategy is more effective and this architecture has resulted in reducing the sprung mass vertical acceleration and pitch accelerations

    Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance

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    Background A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in order to assemble neural circuits that control behavior. Spinal commissural neurons are an attractive model to investigate the multiple guidance cues that control growth cone navigation both pre- and post-midline crossing, as well as along both the dorsal–ventral (D–V) and anterior–posterior (A–P) axes. Accumulating evidence suggests that guidance of spinal commissural axons along the A–P axis is dependent on components of the planar cell polarity (PCP) signaling pathway. In the zebrafish, the earliest born spinal commissural neuron to navigate the midline and turn rostrally is termed commissural primary ascending (CoPA). Unlike mammalian systems, CoPA axons cross the midline as a single axon and allow an analysis of the role of PCP components in anterior pathfinding in single pioneering axons. Results Here, we establish CoPA cells in the zebrafish spinal cord as a model system for investigating the molecular function of planar cell polarity signaling in axon guidance. Using mutant analysis, we show that the functions of Fzd3a and Vangl2 in the anterior turning of commissural axons are evolutionarily conserved in teleosts. We extend our findings to reveal a role for the PCP gene scribble in the anterior guidance of CoPA axons. Analysis of single CoPA axons reveals that these commissural axons become responsive to PCP-dependent anterior guidance cues even prior to midline crossing. When midline crossing is prevented by dcc gene knockdown, ipsilateral CoPA axons still extend axons anteriorly in response to A–P guidance cues. We show that this ipsilateral anterior pathfinding that occurs in the absence of midline crossing is dependent on PCP signaling. Conclusion Our results demonstrate that anterior guidance decisions by CoPA axons are dependent on the function of planar cell polarity genes both prior to and after midline crossing

    California Integrated Waste Management Board

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    California Integrated Waste Management and Recycling Board

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    California Integrated Waste Management Board

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    A Bichromatic Incidence Bound and an Application

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    We prove a new, tight upper bound on the number of incidences between points and hyperplanes in Euclidean d-space. Given n points, of which k are colored red, there are O_d(m^{2/3}k^{2/3}n^{(d-2)/3} + kn^{d-2} + m) incidences between the k red points and m hyperplanes spanned by all n points provided that m = \Omega(n^{d-2}). For the monochromatic case k = n, this was proved by Agarwal and Aronov. We use this incidence bound to prove that a set of n points, no more than n-k of which lie on any plane or two lines, spans \Omega(nk^2) planes. We also provide an infinite family of counterexamples to a conjecture of Purdy's on the number of hyperplanes spanned by a set of points in dimensions higher than 3, and present new conjectures not subject to the counterexample.Comment: 12 page
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