4,618 research outputs found
Optoelectronic control of spin dynamics at near-THz frequencies in magnetically doped quantum wells
We use time-resolved Kerr rotation to demonstrate the optical and electronic
tuning of both the electronic and local moment (Mn) spin dynamics in
electrically gated parabolic quantum wells derived from II-VI diluted magnetic
semiconductors. By changing either the electrical bias or the laser energy, the
electron spin precession frequency is varied from 0.1 to 0.8 THz at a magnetic
field of 3 T and at a temperature of 5 K. The corresponding range of the
electrically-tuned effective electron g-factor is an order of magnitude larger
compared with similar nonmagnetic III-V parabolic quantum wells. Additionally,
we demonstrate that such structures allow electrical modulation of local moment
dynamics in the solid state, which is manifested as changes in the amplitude
and lifetime of the Mn spin precession signal under electrical bias. The large
variation of electron and Mn-ion spin dynamics is explained by changes in
magnitude of the sp−d exchange overlap.Comment: 4 pages, 3 figure
Flavor-twisted boundary condition for simulations of quantum many-body systems
We present an approximative simulation method for quantum many-body systems
based on coarse graining the space of the momentum transferred between
interacting particles, which leads to effective Hamiltonians of reduced size
with the flavor-twisted boundary condition. A rapid, accurate, and fast
convergent computation of the ground-state energy is demonstrated on the
spin-1/2 quantum antiferromagnet of any dimension by employing only two sites.
The method is expected to be useful for future simulations and quick estimates
on other strongly correlated systems.Comment: 6 pages, 2 figure
A Tunable Anomalous Hall Effect in a Non-Ferromagnetic System
We measure the low-field Hall resistivity of a magnetically-doped
two-dimensional electron gas as a function of temperature and
electrically-gated carrier density. Comparing these results with the carrier
density extracted from Shubnikov-de Haas oscillations reveals an excess Hall
resistivity that increases with decreasing temperature. This excess Hall
resistivity qualitatively tracks the paramagnetic polarization of the sample,
in analogy to the ferromagnetic anomalous Hall effect. The data are consistent
with skew-scattering of carriers by disorder near the crossover to
localization
Plasmonic backscattering enhanced inverted photovoltaics
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98669/1/ApplPhysLett_99_113306.pd
CP^n, or, entanglement illustrated
We show that many topological and geometrical properties of complex
projective space can be understood just by looking at a suitably constructed
picture. The idea is to view CP^n as a set of flat tori parametrized by the
positive octant of a round sphere. We pay particular attention to submanifolds
of constant entanglement in CP^3 and give a few new results concerning them.Comment: 28 pages, 9 figure
In situ synchrotron radiation diffraction investigation of the compression behaviour at 350 °C of ZK40 alloys with addition of CaO and Y
The evolution of the microstructure during compression is investigated with in situ synchrotron radiation diffraction in as-cast ZK40, ZK40-2CaO and ZK40-1Y Mg alloys. The specimens were compressed at 350 °C with a strain rate of 10â3 sâ1 until 30% deformation. The Y containing alloy showed the highest 0.2% proof strength in compression of 35 MPa at 350 °C which is double that of the ZK40 alloy, while the CaO added alloy shows a moderate increment at 23 MPa. The Y containing alloy shows some work hardening, while the CaO modified and the ZK40 alloys do not show work hardening after yield. Synchrotron radiation diffraction timelines show that continuous and discontinuous dynamic recrystallization occurs during deformation of the ZK40 alloy while a small amount of dynamic recrystallization was observed in the ZK40-1Y alloy. However, dynamic recrystallization was not present in the ZK40-2CaO alloy. SEM-EBSD analysis conducted on the deformed samples shows a significantly high volume fraction of twins in the Y and CaO containing alloys which was absent in the ZK40 alloy. The modified deformation behaviours observed in the CaO and Y containing alloys were attributed to the presence of intermetallic particles found at the grain boundaries and to the role of Ca and Y in stabilising twinning.The authors acknowledge the Deutsches Elektronen-Synchro-tron for the provision of facilities within the framework of proposal I-20130434.RHBacknowledgesUniversityofSĂŁoPaulofor granting the fellowship 'Bolsa Empreendedorismo'
Larotrectinib efficacy and safety in TRK fusion cancer: An expanded clinical dataset showing consistency in an age and tumor agnostic approach
Background: TRK fusion cancer results from gene fusions involving NTRK1, NTRK2 or NTRK3. Larotrectinib, the first selective TRK inhibitor, has demonstrated an overall response rate (ORR) of 75% with a favorable safety profile in the first 55 consecutively enrolled adult and pediatric patients with TRK fusion cancer (Drilon et al.,NEJM2018). Here, we report the clinical activity of larotrectinib in an additional 35 TRK fusion cancer patients and provide updated follow-up of the primary analysis set (PAS) of 55 patients as of 19thFeb 2018. Methods: Patients with TRK fusion cancer detected by molecular profiling from 3 larotrectinib clinical trials (NCT02122913, NCT02637687, and NCT02576431) were eligible.Larotrectinib was administered until disease progression, withdrawal, or unacceptable toxicity. Disease status was assessed using RECIST version 1.1. Results: As of Feb 2018, by independent review, 6 PRs in the PAS deepened to CRs. The median duration of response (DoR) and progression-free survival in the PAS had still not been reached, with 12.9 months median follow-up. At 1 year, 69% of responses were ongoing, 58% of patients remained progression-free and 90% of patients were alive. An additional 19 children and 25 adults (age range, 0.1-78 years) with TRK fusion cancer were enrolled after the PAS, and included cancers of the salivary gland, thyroid, lung, colon, melanoma, sarcoma, GIST and congenital mesoblastic nephroma. In 35 evaluable patients, the ORR by investigator assessment was 74% (5 CR, 21 PR, 6 SD, 2 PD, 1 not determined). In these patients, with median follow-up of 5.5 months, median DoR had not yet been reached, and 88% of responses were ongoing at 6 months, consistent with the PAS. Adverse events (AEs) were predominantly grade 1, with dizziness, increased AST/ALT, fatigue, nausea and constipation the most common AEs reported in â„ 10% of patients. No AE of grade 3 or 4 related to larotrectinib occurred in more than 5% of patients. Conclusions: TRK fusions are detected in a broad range of tumor types. Larotrectinib is an effective age- and tumor-agnostic treatment for TRK fusion cancer with a positive safety profile. Screening patients for NTRK gene fusions in solid- and brain tumors should be actively considered
Plasma Edge Kinetic-MHD Modeling in Tokamaks Using Kepler Workflow for Code Coupling, Data Management and Visualization
A new predictive computer simulation tool targeting the development of the H-mode pedestal at the plasma edge in tokamaks and the triggering and dynamics of edge localized modes (ELMs) is presented in this report. This tool brings together, in a coordinated and effective manner, several first-principles physics simulation codes, stability analysis packages, and data processing and visualization tools. A Kepler workflow is used in order to carry out an edge plasma simulation that loosely couples the kinetic code, XGC0, with an ideal MHD linear stability analysis code, ELITE, and an extended MHD initial value code such as M3D or NIMROD. XGC0 includes the neoclassical ion-electron-neutral dynamics needed to simulate pedestal growth near the separatrix. The Kepler workflow processes the XGC0 simulation results into simple images that can be selected and displayed via the Dashboard, a monitoring tool implemented in AJAX allowing the scientist to track computational resources, examine running and archived jobs, and view key physics data, all within a standard Web browser. The XGC0 simulation is monitored for the conditions needed to trigger an ELM crash by periodically assessing the edge plasma pressure and current density profiles using the ELITE code. If an ELM crash is triggered, the Kepler workflow launches the M3D code on a moderate-size Opteron cluster to simulate the nonlinear ELM crash and to compute the relaxation of plasma profiles after the crash. This process is monitored through periodic outputs of plasma fluid quantities that are automatically visualized with AVS/Express and may be displayed on the Dashboard. Finally, the Kepler workflow archives all data outputs and processed images using HPSS, as well as provenance information about the software and hardware used to create the simulation. The complete process of preparing, executing and monitoring a coupled-code simulation of the edge pressure pedestal buildup and the ELM cycle using the Kepler scientific workflow system is described in this paper
Renormalized Thermodynamic Entropy of Black Holes in Higher Dimensions
We study the ultraviolet divergent structures of the matter (scalar) field in
a higher D-dimensional Reissner-Nordstr\"{o}m black hole and compute the matter
field contribution to the Bekenstein-Hawking entropy by using the Pauli-Villars
regularization method. We find that the matter field contribution to the black
hole entropy does not, in general, yield the correct renormalization of the
gravitational coupling constants. In particular we show that the matter field
contribution in odd dimensions does not give the term proportional to the area
of the black hole event horizon.Comment: Final Revision Form as to be published in Physical Review D, ReVTeX,
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