FROM ARCHIVE DOCUMENTATION TO ONLINE 3D MODEL VISUALIZATION OF NO LONGER EXISTING STRUCTURES: THE TURIN 1911 PROJECT

Rebuilding the past of cultural heritage through digitization, archiving and visualization by means of digital technology is becoming an emerging issue to ensure the transmission of physical and digital documentation to future generations as evidence of culture, but also to enable present generation to enlarge, facilitate and cross relate data and information in new ways. In this global effort, the digital 3D documentation of no longer existing cultural heritage can be essential for the understanding of past events and nowadays, various digital techniques and tools are developing for multiple purposes. In the present research the entire workflow, starting from archive documentation collection and digitization to the 3D models metrically controlled creation and online sharing, is considered. The technical issues to obtain a detail 3D model are examined stressing limits and potentiality of 3D reconstruction of disappeared heritage and its visualization exploiting three complexes belonging to 1911 Turin World’s Fair

Observational properties of a kink unstable coronal loop

Aims. Previous work on the dynamics of the kink instability has concentrated on the evolution of the magnetic field and associated current sheets. Here we aim to determine the observational consequences of the kink instability in short coronal loops, particularly what images TRACE would record of such an instability. This paper concentrates on the internal m = 1 mode where the kink structure of the instability may not be apparent from the global field shape. This is most relevant to the observation of active region brightenings and coronal bright points. Methods. An existing fluid code was modified to include the TRACE temperature response function in order to calculate temporally and spatially averaged, line of sight images in the 171, 195 and 284 Å band passes for straight, kink unstable flux tubes. Results. Two new fluid effects of the kink instability are discovered: the circular enhancement of the density at the foot points and the appearance of a low density band running across the flux tube. The second of these effects is shown to be imagable by TRACE and hence would be a good candidate observational signature for an internal m = 1 kink unstable loop

Structures in magnetohydrodynamic turbulence: detection and scaling

We present a systematic analysis of statistical properties of turbulent current and vorticity structures at a given time using cluster analysis. The data stems from numerical simulations of decaying three-dimensional (3D) magnetohydrodynamic turbulence in the absence of an imposed uniform magnetic field; the magnetic Prandtl number is taken equal to unity, and we use a periodic box with grids of up to 1536^3 points, and with Taylor Reynolds numbers up to 1100. The initial conditions are either an X-point configuration embedded in 3D, the so-called Orszag-Tang vortex, or an Arn'old-Beltrami-Childress configuration with a fully helical velocity and magnetic field. In each case two snapshots are analyzed, separated by one turn-over time, starting just after the peak of dissipation. We show that the algorithm is able to select a large number of structures (in excess of 8,000) for each snapshot and that the statistical properties of these clusters are remarkably similar for the two snapshots as well as for the two flows under study in terms of scaling laws for the cluster characteristics, with the structures in the vorticity and in the current behaving in the same way. We also study the effect of Reynolds number on cluster statistics, and we finally analyze the properties of these clusters in terms of their velocity-magnetic field correlation. Self-organized criticality features have been identified in the dissipative range of scales. A different scaling arises in the inertial range, which cannot be identified for the moment with a known self-organized criticality class consistent with MHD. We suggest that this range can be governed by turbulence dynamics as opposed to criticality, and propose an interpretation of intermittency in terms of propagation of local instabilities.Comment: 17 pages, 9 figures, 5 table

Micro-Sigmoids as Progenitors of Coronal Jets - Is Eruptive Activity Self-Similarly Multi-Scaled?

Observations from the X-ray telescope (XRT) on Hinode are used to study the nature of X-ray bright points, sources of coronal jets. Several jet events in the coronal holes are found to erupt from small-scale, S-shaped bright regions. This finding suggests that coronal micro-sigmoids may well be progenitors of coronal jets. Moreover, the presence of these structures may explain numerous observed characteristics of jets such as helical structures, apparent transverse motions, and shapes. In analogy to large-scale sigmoids giving rise to coronal mass ejections (CMEs), a promising future task would perhaps be to investigate whether solar eruptive activity, from coronal jets to CMEs, is self-similar in terms of properties and instability mechanisms.Comment: 8 pages, 5 figures, 1 tabl

Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice

Sepsis and septic shock are associated with high mortality and are considered one of the major public health concerns. The onset of sepsis is known as a hyper-inflammatory state that contributes to organ failure and mortality. Recent findings suggest a potential role of two non-receptor protein tyrosine kinases, namely Focal adhesion kinase (FAK) and Proline-rich tyrosine kinase 2 (Pyk2), in the inflammation associated with endometriosis, cancer, atherosclerosis and asthma. Here we investigate the role of FAK-Pyk2 in the pathogenesis of sepsis and the potential beneficial effects of the pharmacological modulation of this pathway by administering the potent reversible dual inhibitor of FAK and Pyk2, PF562271 (PF271) in a murine model of cecal ligation and puncture (CLP)-induced sepsis. Five-month-old male C57BL/6 mice underwent CLP or Sham surgery and one hour after the surgical procedure, mice were randomly assigned to receive PF271 (25 mg/kg, s.c.) or vehicle. Twenty-four hours after surgery, organs and plasma were collected for analyses. In another group of mice, survival rate was assessed every 12 h over the subsequent 5 days. Experimental sepsis led to a systemic cytokine storm resulting in the formation of excessive amounts of both pro-inflammatory cytokines (TNF-α, IL-1β, IL-17 and IL-6) and the anti-inflammatory cytokine IL-10. The systemic inflammatory response was accompanied by high plasma levels of ALT, AST (liver injury), creatinine, (renal dysfunction) and lactate, as well as a high, clinical severity score. All parameters were attenuated following PF271 administration. Experimental sepsis induced an overactivation of FAK and Pyk2 in liver and kidney, which was associated to p38 MAPK activation, leading to increased expression/activation of several pro-inflammatory markers, including the NLRP3 inflammasome complex, the adhesion molecules ICAM-1, VCAM-1 and E-selectin and the enzyme NOS-2 and myeloperoxidase. Treatment with PF271 inhibited FAK-Pyk2 activation, thus blunting the inflammatory abnormalities orchestrated by sepsis. Finally, PF271 significantly prolonged the survival of mice subjected to CLP-sepsis. Taken together, our data show for the first time that the FAK-Pyk2 pathway contributes to sepsis-induced inflammation and organ injury/dysfunction and that the pharmacological modulation of this pathway may represents a new strategy for the treatment of sepsis