213 research outputs found
Nonlinear double Compton scattering in the full quantum regime
A detailed analysis of the process of two photon emission by an electron
scattered from a high-intensity laser pulse is presented. The calculations are
performed in the framework of strong-field QED and include exactly the presence
of the laser field, described as a plane wave. We investigate the full quantum
regime of interaction, where photon recoil plays an essential role in the
emission process, and substantially alters the emitted photon spectra as
compared to those in previously-studied regimes. We provide a semiclassical
explanation for such differences, based on the possibility of assigning a
trajectory to the electron in the laser field before and after each quantum
photon emission. Our numerical results indicate the feasibility of
investigating experimentally the full quantum regime of nonlinear double
Compton scattering with already available plasma-based electron accelerator and
laser technology.Comment: 5 pages, 3 figure
BORIS (CTCFL) Is Not Expressed in Most Human Breast Cell Lines and High Grade Breast Carcinomas
BORIS (CTCFL) is the only known paralog of the versatile regulatory protein CTCF, a multifunctional DNA binding protein that mediates distinct gene regulatory functions involved in cell growth, differentiation, and apoptosis. Unlike CTCF, the expression of BORIS is normally restricted to specific cells in testes (the only cells where CTCF is not expressed), where it may play a role in reprogramming the methylation pattern of male germ line DNA. Frequent amplification of the 20q13.2 region, which contains the BORIS gene, and expression of BORIS transcripts in diverse human tumors and cell lines have led to the hypothesis that aberrant expression of BORIS may play a role in tumorigenesis by interfering with CTCF functions. However, recent studies using more quantitative methods indicate low frequency of BORIS expression in melanoma, ovarian, prostate, and bladder carcinomas. To investigate the relationship between chromosome 20q13 amplification and BORIS mRNA levels within breast cancer cell lines and tissues, we developed a quantitative RT-PCR assay to measure the levels of BORIS mRNA. Endpoint RT-PCR assays were also used to investigate the possible expression of alternatively spliced variants. Using multiple primer sets and controls, we found that neither mature BORIS transcripts nor spliced variants are commonly expressed at detectable levels in malignant breast cells or tissues, although endogenous BORIS transcripts can be induced in MCF-7 cells following 5-aza-2′-deoxycytidine treatment. In conclusion, in most breast cancer cells, endogenous BORIS is unlikely to be expressed at sufficient levels to interfere with CTCF functions. Thus it is improbable that aberrant BORIS expression plays a role in most human breast cancers
Benchmarking of 3D space charge codes using direct phase space measurements from photoemission high voltage DC gun
We present a comparison between space charge calculations and direct
measurements of the transverse phase space for space charge dominated electron
bunches after a high voltage photoemission DC gun followed by an emittance
compensation solenoid magnet. The measurements were performed using a
double-slit setup for a set of parameters such as charge per bunch and the
solenoid current. The data is compared with detailed simulations using 3D space
charge codes GPT and Parmela3D with initial particle distributions created from
the measured transverse and temporal laser profiles. Beam brightness as a
function of beam fraction is calculated for the measured phase space maps and
found to approach the theoretical maximum set by the thermal energy and
accelerating field at the photocathode.Comment: 11 pages, 23 figures. submitted to Phys Rev ST-A
New phase structure of the Nambu -- Jona - Lasinio model at nonzero chemical potential
It is shown that in the Nambu -- Jona - Lasinio model at nonzero chemical
potential there are two different massive phases with spontaneously broken
chiral symmetry. In one of them particle density is identically zero, in
another phase it is not equal to zero. The transition between phases is a phase
transition of the second order.Comment: 8 pages, LaTeX, no figures
Simulation of the transit-time optical stochastic cooling process in the Cornell Electron Storage Ring
In preparation for a demonstration of optical stochastic cooling in the
Cornell Electron Storage Ring (CESR) we have developed a particle tracking
simulation to study the relevant beam dynamics. Optical radiation emitted in
the pickup undulator gives a momentum kick to that same particle in the kicker
undulator. The optics of the electron bypass from pickup to kicker couples
betatron amplitude and momentum offset to path length so that the momentum kick
reduces emittance and momentum spread. Nearby electrons contribute an
incoherent noise. Layout of the bypass line is presented that accommodates
optics with a range of transverse and longitudinal cooling parameters. The
simulation is used to determine cooling rates and their dependence on bunch and
lattice parameters for bypass optics with distinct emittance and momentum
acceptance
Formation of the internal structure of solids under severe action
On the example of a particular problem, the theory of vacancies, a new form
of kinetic equations symmetrically incorporation the internal and free energies
has been derived. The dynamical nature of irreversible phenomena at formation
and motion of defects (dislocations) has been analyzed by a computer
experiment. The obtained particular results are extended into a thermodynamic
identity involving the law of conservation of energy at interaction with an
environment (the 1st law of thermodynamics) and the law of energy
transformation into internal degree of freedom (relaxation). The identity is
compared with the analogous Jarzynski identity. The approach is illustrated by
simulation of processes during severe plastic deformation, the Rybin kinetic
equation for this case has been derived.Comment: 9 pages, 5 figure
Russia, Mongolia, China: Historical Projections of Interaction between the Nations
Introduction. The Russia-Mongolia-China Economic Corridor (RCM) is an important regional initiative aimed at expanding ties and developing economic cooperation in Northeast Asia. Insights into historical contexts of the corridor are essential for understanding its current dynamics and future prospects. Goals. The article attempts a comprehensive analysis of historical aspects related to the Russia-China-Mongolia Economic Corridor, with due account of historical projections, geopolitical factors, and historical trade routes that had shaped economic relations between the nations. The paper shall focus on the mentioned aspects to shed light on the long-standing historical ties that do facilitate the present-day emergence and development of the corridor. Materials and methods. The study employs a variety of sources, such as intergovernmental agreements, statistical digests, eyewitness accounts of the past, official reports, and speeches of top-ranking officials. The analytical tools that secure a systematic research approach include as follows: a retrospective analysis method, comparative historical and typological ones, that of systemic analysis. Results. Insights into actual statistical data yield an analytical description of the current situation in cross-border cargo flows (the Russia-Mongolia-China section), including some possibilities of transport infrastructure, and particularly those of the Ulaanbaatar Railway. Special attention is paid to challenges and risks arising from some projects of the economic corridor. Conclusions. The historical projections of trans-Eurasian trade routes — whether caravan tracks of the past or present-day infrastructure projects — attest to that communities of both the East and the West do need and show interest in such interaction. Russia and China’s imperial environments are characterized by specific dynamic and rhythmic patterns of trade and cultural communication that used to (and still do) shape somewhat unique geography of the routes. The famous Tea Road integrated a large number of cities in Russia and China. The opening of China, its industrialization and capitalization paved the way to its development and inclusion into global markets. These were followed by its transformation into a modern world power. Historical insights may yield better understandings of past successes and declines. One should also keep it in mind that the present historical legacy as such largely rests on the pillars of enormous political transformations witnessed by the twentieth century when the specific geopolitical agenda tied Mongolia to the Soviet Union with dozens (and hundreds) of strong links. Russia’s turn to the East and its strategic alliance with China are to give further impulses to trans-regional and trans-continental projects
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