1,981 research outputs found
Re-configurable, multi-channel, high-speed FBG strain sensing system for vibration analysis in oil risers
Eight re-configurable, synchronized resonant cavity time-division- multiplexed FBG sensor interrogators provide 16,800 high-resolution measurements-per-second from 280 axially embedded strain sensors, for the analysis of vortex-shedding-induced vibration and bending in a composite oil riser pipe
Memory-Based Snowdrift Game on Networks
We present a memory-based snowdrift game (MBSG) taking place on networks. We
found that, when a lattice is taken to be the underlying structure, the
transition of spatial patterns at some critical values of the payoff parameter
is observable for both 4 and 8-neighbor lattices. The transition points as well
as the styles of spatial patterns can be explained by local stability analysis.
In sharp contrast to previously reported results, cooperation is promoted by
the spatial structure in the MBSG. Interestingly, we found that the frequency
of cooperation of the MBSG on a scale-free network peaks at a specific value of
the payoff parameter. This phenomenon indicates that properly encouraging
selfish behaviors can optimally enhance the cooperation. The memory effects of
individuals are discussed in detail and some non-monotonous phenomena are
observed on both lattices and scale-free networks. Our work may shed some new
light on the study of evolutionary games over networks.Comment: 6 pages, 6 figures, to be published in Phys. Rev.
A dynamically extending exclusion process
An extension of the totally asymmetric exclusion process, which incorporates
a dynamically extending lattice is explored. Although originally inspired as a
model for filamentous fungal growth, here the dynamically extending exclusion
process (DEEP) is studied in its own right, as a nontrivial addition to the
class of nonequilibrium exclusion process models. Here we discuss various
mean-field approximation schemes and elucidate the steady state behaviour of
the model and its associated phase diagram. Of particular note is that the
dynamics of the extending lattice leads to a new region in the phase diagram in
which a shock discontinuity in the density travels forward with a velocity that
is lower than the velocity of the tip of the lattice. Thus in this region the
shock recedes from both boundaries.Comment: 20 pages, 12 figure
Networking Effects on Cooperation in Evolutionary Snowdrift Game
The effects of networking on the extent of cooperation emerging in a
competitive setting are studied. The evolutionary snowdrift game, which
represents a realistic alternative to the well-known Prisoner's Dilemma, is
studied in the Watts-Strogatz network that spans the regular, small-world, and
random networks through random re-wiring. Over a wide range of payoffs, a
re-wired network is found to suppress cooperation when compared with a
well-mixed or fully connected system. Two extinction payoffs, that characterize
the emergence of a homogeneous steady state, are identified. It is found that,
unlike in the Prisoner's Dilemma, the standard deviation of the degree
distribution is the dominant network property that governs the extinction
payoffs.Comment: Changed conten
Do people really want to be nudged towards healthy lifestyles?
This paper assesses Thaler and Sunsteinâs claim that policies that nudge individuals towards healthy lifestyles promote the welfare of those individuals, as judged by themselves. I argue that Thaler and Sunstein switch between two different interpretations of that clause. One interpretation gives the clause a wide range of applicability, but drains it of its content as a repudiation of paternalism. The other interpretation makes it more meaningful to say that people want to make the choices they are being nudged towards, but applies to a much narrower range of cases than Thaler and Sunstein have in mind
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Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors
The nuclear Dbf2-related protein kinases 1 and 2 (NDR1/2) are closely-related AGC family kinases that are strongly conserved through evolution. In mammals, they are activated inter alia by phosphorylation of an hydrophobic domain threonine-residue [NDR1(Thr-444)/NDR2(Thr-442)] by an extrinsic protein kinase followed by autophosphorylation of a catalytic domain serine-residue [NDR1(Ser-281)/NDR2(Ser-282)]. We examined NDR1/2 expression and regulation in primary cultures of neonatal rat cardiac myocytes and in perfused adult rat hearts. In myocytes, transcripts for NDR2, but not NDR1, were induced by the hypertrophic agonist, endothelin-1. NDR1(Thr-444) and NDR2(Thr-442) were rapidly phosphorylated (maximal in 15-30 min) in myocytes exposed to some phosphoprotein Ser-/Thr-phosphatase 1/2 inhibitors (calyculin A, okadaic acid) and, to a lesser extent, by hyperosmotic shock, low concentrations of H(2)O(2), or chelerythrine. In myocytes adenovirally-transduced to express FLAG-NDR2 (which exhibited a mainly-cytoplasmic localisation), the same agents increased FLAG-NDR2 activity as assessed by in vitro protein kinase assays, indicative of FLAG-NDR2(Ser-282/Thr-442) phosphorylation. Calyculin A-induced phosphorylation of NDR1(Thr-444)/NDR2(Thr-442) and activation of FLAG-NDR2 were inhibited by staurosporine, but not by other protein kinase inhibitors tested. In ex vivo rat hearts, NDR1(Thr-444)/NDR2(Thr-442) were phosphorylated in response to ischaemia-reperfusion or calyculin A. From a pathological viewpoint, we conclude that activities of NDR1 and NDR2 are responsive to cytotoxic stresses in heart preparations and this may represent a previously-unidentified response to myocardial ischaemia in vivo
A model of hyphal tip growth involving microtubule-based transport
We propose a simple model for mass transport within a fungal hypha and its
subsequent growth. Inspired by the role of microtubule-transported vesicles, we
embody the internal dynamics of mass inside a hypha with mutually excluding
particles progressing stochastically along a growing one-dimensional lattice.
The connection between long range transport of materials for growth, and the
resulting extension of the hyphal tip has not previously been addressed in the
modelling literature. We derive and analyse mean-field equations for the model
and present a phase diagram of its steady state behaviour, which we compare to
simulations. We discuss our results in the context of the filamentous fungus,
Neurospora crassa.Comment: 5 pages, 5 figure
Characterising competitive equilibrium in terms of opportunity
This paper analyses alternative profiles of opportunity sets for individuals in an exchange economy, without assuming that individualsâ choices reveal coherent preferences. It introduces the concept of a âmarket-clearing single-price regimeâ, representing a profile of opportunity sets consistent with competitive equilibrium. It also proposes an opportunity-based normative criterion, the Strong Opportunity Criterion, which is analogous with the core in preference-based analysis. It shows that every market-clearing single-price regime satisfies the Strong Opportunity Criterion and that, in the limit as an economy is replicated, only such regimes have this property
Adaptation and extension of the European recommendations (EACD) on Developmental Coordination Disorder (DCD) for the UK context
Background. Developmental Coordination Disorder (DCD) affects the learning and performance of everyday motor skills. It commonly co-occurs with other developmental disorders and a range of associated psycho-social impairments. Recent evidence-based guidelines on diagnosis, assessment and intervention provide valuable information for practitioners. However these are directed primarily at German-speaking countries and focus on work with children.
Aim. The aim of this project was to consider the application of these guidelines in the UK and to extend them for use with adults with DCD.
Methods. Individuals with DCD, parents and professionals from a wide range of disciplines were invited to two workshops to discuss and debate the guidelines, to adapt them for the UK and produce dissemination materials.
Results. A working definition of DCD was agreed, minor revisions were made to the guidelines to reflect the UK context, an extension for adults was compiled and a series of leaflets was produced to disseminate this information to health and education professionals, parents and employers.
Conclusions. This work will raise awareness of the condition across different professional groups. It provides information to help those working with children and adults with DCD in the UK to assist in the process of diagnosis, assessment and intervention
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