Qualitative Indicators of Microbial Cells of Yersinia pestis EV Strain Depending on Their Morphological Traits in Different Temperature Conditions of Manufacturing of Plague Vaccine Preparation

The preference of the (21±1) °C temperature for cultivation of the vaccine strain Yersinia pestis EV in the live plague vaccine biomass production to (27±1) °C is experimentally confirmed. An original interpretation of the mechanism of small cells stability that are formed at (21±1) °C has been proposed. This interpretation stipulates a smaller damaging effect of steam molecules during sublimation in the process of lyophilization

Влияние молекулярной массы на процесс электроформования волокнистых материалов, полученных из растворов полиакрилонитрила

In the article influence of the molecular weight of polyacrylonitrile on electrospinning process and also on the diameter and mechanical properties of the obtained fibers and fiber materials are considered. Polymers with molecular weight from 280 000 to 700 000 were investigated. Fibers with a diameter from 200 to 1100 nm were obtained.В статье рассматривается влияние молекулярной массы полиакрилонитрила на диаметр и механические свойства полученных волокон и волокнистых материалов. Исследованы полимеры с молекулярной массой от 280 000 до 700 000. Получены волокна с диаметром от 200-1100 нм

Исследование процесса растяжения жидкой полимерной струи в электрическом поле из растворов полиакрилонитрила

The article considers stretching of liquid polyacrylonitrile jet in electrostatic field. Polymers with molecular weight from 130 000 to 700 000 were investigated. Regularities of stretching of the jet based on polyacrylonitrile solutions were determined.В статье рассматривается процесс растяжения жидкой полимерной струи растворов полиакрилонитрила (ПАН) находящейся в электрическом поле. Исследованы полимеры с молекулярной массой от 130 000 до 700 000. Установлены основные закономерности процесса растяжения струи на основе растворов ПАН

Influence of molecular weight on electrospinning of fiber materials obtained from solutions of polyacrylonitrile

In the article influence of the molecular weight of polyacrylonitrile on electrospinning process and also on the diameter and mechanical properties of the obtained fibers and fiber materials are considered. Polymers with molecular weight from 280 000 to 700 000 were investigated. Fibers with a diameter from 200 to 1100 nm were obtained

Investigation of stretching process of liquid jet being in electrostatic field from polyacrylonitrile solutions

The article considers stretching of liquid polyacrylonitrile jet in electrostatic field. Polymers with molecular weight from 130 000 to 700 000 were investigated. Regularities of stretching of the jet based on polyacrylonitrile solutions were determined

Comparative Analysis of Experimental Series of Plague Live Vaccine as for Viability and Thermostability Indices

Comparative analysis of specified indices (viability, thermostability) of plague live vaccine preparations, produced in accordance with different biotechnological production schemes, have been carried out. Shown is that the combination of optimal temperature for Yersinia pestis strain EV biomass propagation (21±1) °C as well as optimal concentration proportion of bacteria and stabilizer in suspension with decreased optical density and volume facilitates effectual moisture removal out of preparation, thus stabilizing microbial cells viability index in the process of storage