The shortest synthetic route to puromycin analogues using a modified robins approach

International audienceWe are reporting on the utility of commercial vinyl isocyanate for a practical synthetic route from adenosine to N(6)-bis-demethylpuromycin in seven steps and 65% overall yield. A clean one-pot conversion of 3'-bromo-2'-carbamoyl derivative 8 to 3'-amino-3'-deoxyadenosine derivative 10 is the main feature of this synthetic pathway. This synthesis is the shortest synthetic route toward 3'-(aminoacylamido)deoxyadenosines to date

Bio-inspired oxidation of methane in water catalyzed by N-bridged diiron phthalocyanine complex

Sorokin, Alexander B. Kudrik, Evgeny V. Bouchu, DenisA stable mu-nitrido diiron phthalocyanine activates H2O2 to oxidize CH4 in water at 25-60 degrees C to methanol, formaldehyde and formic acid as evidenced using C-13 and O-18 labelling

Human leukocyte elastase hydrolysis of peptides derived from human elastin exon 24

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Lettre de Jean-Baptiste Colbert (contrôleur général des finances) à Henri d'Aguesseau (intendant de Languedoc), Thomas-Alexandre Morant (intendant d'Aix), et Claude Bouchu (intendant de Bourgogne) datée du 02 janvier 1682, à Paris

Lettre de Jean-Baptiste Colbert (contrôleur général des finances) à Henri d'Aguesseau (intendant de Languedoc), Thomas-Alexandre Morant (intendant d'Aix), et Claude Bouchu (intendant de Bourgogne) datée du 02 janvier 1682, à Paris. In: Lettres, instructions et mémoires de Colbert, publiées par Pierre Clément. Tome II. Ire partie. Finances, impôts, monnaies. Paris : Imprimerie impériale, 1863. pp. 172-173

Stable N-bridged diiron (IV) phthalocyanine cation radical complexes: synthesis and properties

Afanasiev, Pavel Bouchu, Denis Kudrik, Evgeny V. Millet, Jean-Marc M. Sorokin, Alexander B.Oxidation of N-bridged diiron tetra-tert-butylphthalocyanine ((FePcBu)-Bu-t)(2)N with (BuOOH)-Bu-t in halogenated solvents afforded mu-nitrido diiron (IV) phthalocyanine cation radical complexes, (X)PcFeIV-N-(FePc+center dot)-Pc-IV(X) (X = Cl, Br), as evidenced by UV-vis, electron paramagnetic resonance (EPR), electrospray ionization mass spectrometry (ESI-MS), Mossbauer, X-ray absorption near edge structure (XANES) and extended X-ray absorption. ne structure (EXAFS) data. Continuous introduction ESI-MS showed the initial formation of the t-butylperoxo diiron complex (BuOO)-Bu-t-((FePcBu)-Bu-t)(2)N followed by intermediate formation of a monohalogenated adduct which gave the dihalogenated complex as final stable product. Fe K-edge EXAFS analysis of (X)PcFeIV-N-(FePc+center dot)-Pc-IV(X) showed bridging N atom at a distance of 1.69(1) angstrom. The distance between two equivalent hexacoordinated in-plane iron (IV) centers is 3.39(1) angstrom. Fe-X bond lengths are 2.33 and 2.54 angstrom for X = Cl and Br, respectively. The use of (Cl)PcFeIV-N-(FePc+center dot)-Pc-IV(Cl) for the catalytic oxidation of organic substrates has been shown for the first time

Lettre de Jean-Baptiste Colbert (contrôleur général des finances) à Henri d'Aguesseau (intendant de Languedoc), Thomas-Alexandre Morant (intendant d'Aix), et Claude Bouchu (intendant de Bourgogne) datée du 02 janvier 1682, à Paris

Lettre de Jean-Baptiste Colbert (contrôleur général des finances) à Henri d'Aguesseau (intendant de Languedoc), Thomas-Alexandre Morant (intendant d'Aix), et Claude Bouchu (intendant de Bourgogne) datée du 02 janvier 1682, à Paris. In: Lettres, instructions et mémoires de Colbert, publiées par Pierre Clément. Tome II. Ire partie. Finances, impôts, monnaies. Paris : Imprimerie impériale, 1863. pp. 172-173

High-valent diiron species generated from N-bridged diiron phthalocyanine and H2O2

BIOVERT:RAFFINAGE+PAF:EKU:AS

Experimental characterization of the overburden effect

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